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  1. Previous intraindividual comparative studies evaluating gadobutrol and gadoteridol for contrast-enhanced magnetic resonance imaging (MRI) of brain tumours have relied on subjective image assessment, potentiall...

    Authors: Matthew J. Kuhn, Julia W. Patriarche, Douglas Patriarche, Miles A. Kirchin, Massimo Bona and Gianpaolo Pirovano

    Citation: European Radiology Experimental 2021 5:46

    Content type: Original article

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  2. Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an...

    Authors: Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Jeff Kershaw, Yasuhiko Tachibana, Nobuhiro Nitta, Sayaka Shibata, Masato Yasui, Makoto Higuchi and Takayuki Obata

    Citation: European Radiology Experimental 2021 5:44

    Content type: Original article

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  3. Dual-source dual-energy computed tomography (DECT) offers the potential for opportunistic osteoporosis screening by enabling phantomless bone mineral density (BMD) quantification. This study sought to assess t...

    Authors: Vitali Koch, Nils Große Hokamp, Moritz H. Albrecht, Leon D. Gruenewald, Ibrahim Yel, Jan Borggrefe, Stefan Wesarg, Katrin Eichler, Iris Burck, Tatjana Gruber-Rouh, Lukas Lenga, Thomas J. Vogl, Simon S. Martin, Julian L. Wichmann, Renate M. Hammerstingl, Leona S. Alizadeh…

    Citation: European Radiology Experimental 2021 5:43

    Content type: Original article

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  4. Chronic pulmonary embolism (CPE) is a life-threatening disease easily misdiagnosed on computed tomography. We investigated a three-dimensional convolutional neural network (CNN) algorithm for detecting hypoper...

    Authors: Tuomas Vainio, Teemu Mäkelä, Sauli Savolainen and Marko Kangasniemi

    Citation: European Radiology Experimental 2021 5:45

    Content type: Original article

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  5. In hepatobiliary imaging, systems detect the total amount of agents originating from extracellular space, bile canaliculi, and hepatocytes. They add in situ concentration of each compartment corrected by its resp...

    Authors: Catherine M. Pastor, Florian Joly, Valérie Vilgrain and Philippe Millet

    Citation: European Radiology Experimental 2021 5:42

    Content type: Original article

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  6. Transperineal laser ablation (TPLA) of the prostate is a novel, mini-invasive option for men with lower urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH). Our aim was to assess the impact ...

    Authors: Guglielmo Manenti, Tommaso Perretta, Antonello Calcagni, Donatella Ferrari, Colleen P. Ryan, Federico Fraioli, Rosaria Meucci, Andrea Malizia, Valerio Iacovelli, Enrico Finazzi Agrò and Roberto Floris

    Citation: European Radiology Experimental 2021 5:41

    Content type: Original article

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  7. Our aim was to demonstrate that automated detection and classification of breast microcalcifications, according to Breast Imaging Reporting and Data System (BI-RADS) categorisation, can be improved with the su...

    Authors: Kosmia Loizidou, Galateia Skouroumouni, Costas Pitris and Christos Nikolaou

    Citation: European Radiology Experimental 2021 5:40

    Content type: Original article

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  8. Assessment of image noise is a relevant issue in computed tomography (CT). Noise is routinely measured by the standard deviation of density values (Hounsfield units, HU) within a circular region of interest (R...

    Authors: Hendrik Joost Wisselink, Gert Jan Pelgrim, Mieneke Rook, Ivan Dudurych, Maarten van den Berge, Geertruida H. de Bock and Rozemarijn Vliegenthart

    Citation: European Radiology Experimental 2021 5:39

    Content type: Technical note

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  9. Dual-energy CT (DECT) has emerged into clinical routine as an imaging technique with unique postprocessing utilities that improve the evaluation of different body areas. The virtual non-calcium (VNCa) reconstr...

    Authors: Tommaso D’Angelo, Moritz H. Albrecht, Danilo Caudo, Silvio Mazziotti, Thomas J. Vogl, Julian L. Wichmann, Simon Martin, Ibrahim Yel, Giorgio Ascenti, Vitali Koch, Giuseppe Cicero, Alfredo Blandino and Christian Booz

    Citation: European Radiology Experimental 2021 5:38

    Content type: Narrative review

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  10. In the last 20 years, ultra-high field (UHF) magnetic resonance imaging (MRI) has become an outstanding research tool for the study of the human brain, with 90 of these scanners installed today, worldwide. The...

    Authors: Mirco Cosottini and Luca Roccatagliata

    Citation: European Radiology Experimental 2021 5:37

    Content type: Editorial

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  11. Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment operating at static magnetic field of 7 tesla (7 T) and above, enable the acquisition of data with greatly improved signal-to-noise r...

    Authors: Emrah Düzel, Mauro Costagli, Graziella Donatelli, Oliver Speck and Mirco Cosottini

    Citation: European Radiology Experimental 2021 5:36

    Content type: Narrative review

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  12. Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provi...

    Authors: Behroze Vachha and Susie Y. Huang

    Citation: European Radiology Experimental 2021 5:35

    Content type: Narrative review

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  13. We investigated mitral valve annular geometry changes during the cardiac cycle in patients with severe mitral regurgitation (MR) who underwent cardiac computed tomography angiography (CCTA) prior to percutaneo...

    Authors: Anna Palmisano, Valeria Nicoletti, Caterina Colantoni, Caterina Beatrice Monti, Luigi Pannone, Davide Vignale, Fatemeh Darvizeh, Eustachio Agricola, Simone Schaffino, Francesco De Cobelli and Antonio Esposito

    Citation: European Radiology Experimental 2021 5:34

    Content type: Original article

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  14. To evaluate the feasibility of two-colour index maps containing combined diffusion and perfusion information from simplified intravoxel incoherent motion (IVIM) for liver lesion malignancy assessment.

    Authors: Petra Mürtz, Narine Mesropyan, Alois M. Sprinkart, Wolfgang Block, Julian A. Luetkens, Ulrike Attenberger and Claus C. Pieper

    Citation: European Radiology Experimental 2021 5:33

    Content type: Original article

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  15. Angiogenesis is prominent in metastatic renal cell carcinoma (mRCC). We compared two angiogenesis assessment methods: dynamic contrast-enhanced computed tomography (DCE-CT)-derived blood volume (BV) and blood ...

    Authors: Aska Drljevic-Nielsen, Finn Rasmussen, Patricia Switten Nielsen, Christina Stilling, Kennet Thorup, Jill Rachel Mains, Hans Henrik Torp Madsen and Frede Donskov

    Citation: European Radiology Experimental 2021 5:32

    Content type: Original article

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  16. Two-dimensional (2D) ultrasound is well established for thyroid nodule assessment and treatment guidance. However, it is hampered by a limited field of view and observer variability that may lead to inaccurate...

    Authors: T. Boers, S. J. Braak, M. Versluis and S. Manohar

    Citation: European Radiology Experimental 2021 5:31

    Content type: Original article

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  17. With advancements in computer systems, computer graphics and medical imaging technologies, clinicians strive for a personalised approach to patient treatment. Therefore, the production of personalised surgical...

    Authors: Luka Šimić, Vjekoslav Kopačin, Ivan Mumlek, Josip Butković and Vedran Zubčić

    Citation: European Radiology Experimental 2021 5:30

    Content type: Technical note

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  18. Telesonography systems have been developed to overcome barriers to accessing diagnostic ultrasound for patients in rural and remote communities. However, most previous telesonography systems have been designed...

    Authors: Mohammed Obaid, Qianwei Zhang, Scott J. Adams, Reza Fotouhi and Haron Obaid

    Citation: European Radiology Experimental 2021 5:29

    Content type: Original article

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  19. To evaluate the performance of a decision support system (DSS) based on radiomics and machine learning in predicting the risk of malignancy of ovarian masses (OMs) from transvaginal ultrasonography (TUS) and s...

    Authors: Valentina Chiappa, Matteo Interlenghi, Giorgio Bogani, Christian Salvatore, Francesca Bertolina, Giuseppe Sarpietro, Mauro Signorelli, Dominique Ronzulli, Isabella Castiglioni and Francesco Raspagliesi

    Citation: European Radiology Experimental 2021 5:28

    Content type: Original article

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  21. Cerebrospinal fluid shunts in the treatment of hydrocephalus, although associated with clinical benefit, have a high failure rate with repeat computed tomography (CT) imaging resulting in a substantial cumulat...

    Authors: David J. Ryan, Richard G. Kavanagh, Stella Joyce, Mika O’Callaghan Maher, Niamh Moore, Aisling McMahon, Deirdre Hussey, Michael G. J. O’Sullivan, Gerald Wyse, Noel Fanning, Owen J. O’Connor and Michael M. Maher

    Citation: European Radiology Experimental 2021 5:26

    Content type: Original article

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  22. Computed tomography angiography (CTA) imaging is needed in current guideline-based stroke diagnosis, and infarct core size is one factor in guiding treatment decisions. We studied the efficacy of a convolution...

    Authors: Lasse Hokkinen, Teemu Mäkelä, Sauli Savolainen and Marko Kangasniemi

    Citation: European Radiology Experimental 2021 5:25

    Content type: Original article

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  23. The aim of this study was to quantitatively benchmark iodine imaging across specific virtual monoenergetic energy levels, iodine maps and virtual non-contrast images with different phantom sizes and iodine con...

    Authors: Vanja Harsaker, Kristin Jensen, Hilde Kjernlie Andersen and Anne Catrine Martinsen

    Citation: European Radiology Experimental 2021 5:24

    Content type: Original article

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  24. Magnetic resonance imaging (MRI) has become an essential diagnostic modality for congenital disorders of the central nervous system. Recent advancements have transformed foetal MRI into a clinically feasible t...

    Authors: Andras Jakab, Kelly Payette, Luca Mazzone, Sonja Schauer, Cécile Olivia Muller, Raimund Kottke, Nicole Ochsenbein-Kölble, Ruth Tuura, Ueli Moehrlen and Martin Meuli

    Citation: European Radiology Experimental 2021 5:23

    Content type: Narrative review

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  25. There is limited scientific evidence on the potential of spectral computed tomography (SCT) for differentiation of nodules in the cirrhotic liver. We aimed to assess SCT-generated material density (MD) paramet...

    Authors: Shalini Thapar Laroia, Komal Yadav, Senthil Kumar, Archana Rastogi, Guresh Kumar and Shiv Kumar Sarin

    Citation: European Radiology Experimental 2021 5:22

    Content type: Original article

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  26. On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) pandemic. The expert organisations recommend more cautious use of thoracic computed tomography (CT), opting for...

    Authors: Victor Gombolevskiy, Sergey Morozov, Valeria Chernina, Ivan Blokhin and Jenia Vassileva

    Citation: European Radiology Experimental 2021 5:21

    Content type: Technical note

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  27. PRIMAGE is a European Commission-financed project dealing with medical imaging and artificial intelligence aiming to create an imaging biobank in oncology. The project includes a task dedicated to the interope...

    Authors: Camilla Scapicchio, Michela Gabelloni, Sara Maria Forte, Leonor Cerdá Alberich, Lorenzo Faggioni, Rita Borgheresi, Paola Erba, Fabiola Paiar, Luis Marti-Bonmati and Emanuele Neri

    Citation: European Radiology Experimental 2021 5:20

    Content type: Methodology

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  28. Magnetic resonance imaging (MRI) is the modality of choice for evaluating soft tissue damage along the spine in the emergency setting, yet access and fast protocol availability are limited. We assessed the per...

    Authors: Nico Sollmann, Charlotte Rüther, Simon Schön, Claus Zimmer, Thomas Baum and Jan S. Kirschke

    Citation: European Radiology Experimental 2021 5:19

    Content type: Original article

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  29. In this study, we investigated the influence of beam hardening on the dual-energy computed tomography (DECT) values of iodine maps, virtual monoenergetic (VME) images, and virtual non-contrast (VNC) images. 32...

    Authors: Risa Kanatani, Takashi Shirasaka, Tsukasa Kojima, Toyoyuki Kato and Masateru Kawakubo

    Citation: European Radiology Experimental 2021 5:18

    Content type: Technical note

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  30. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Cristian Giuseppe Monaco, Federico Zaottini, Simone Schiaffino, Alessandro Villa, Gianmarco Della Pepa, Luca Alessandro Carbonaro, Laura Menicagli, Andrea Cozzi, Serena Carriero, Francesco Arpaia, Giovanni Di Leo, Davide Astengo, Ilan Rosenberg and Francesco Sardanelli

    Citation: European Radiology Experimental 2021 5:17

    Content type: Correction

    Published on:

    The original article was published in European Radiology Experimental 2020 4:68

  31. Our aim was to compare the diagnostic performance of quantitative dual-layer spectral computed tomography (DLSCT) and axillary ultrasound (US) for diagnosing lymph node metastases in breast cancer patients.

    Authors: Thomas Winther Buus, Mads Sandahl, Kennet Sønderstgaard Thorup, Finn Rasmussen, Søren Redsted, Peer Christiansen, Anders Bonde Jensen and Erik Morre Pedersen

    Citation: European Radiology Experimental 2021 5:16

    Content type: Original article

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  32. Although dorsal/palmar tilt, radial inclination (RI), and ulnar variance (UV) are measurements commonly performed in wrist radiographs, the impact of forearm rotation on those measurements during the radiograp...

    Authors: Janni Jensen, Hans B. Tromborg, Benjamin S. B. Rasmussen, Oke Gerke, Trine Torfing, Helle Precht and Ole Graumann

    Citation: European Radiology Experimental 2021 5:15

    Content type: Original article

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  33. Ischemic heart disease and its sequelae are one of the major contributors to morbidity and mortality worldwide. Over the last decades, technological developments have strengthened the role of noninvasive imagi...

    Authors: Tilman Emrich, Moritz Halfmann, U. Joseph Schoepf and Karl-Friedrich Kreitner

    Citation: European Radiology Experimental 2021 5:14

    Content type: Narrative review

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  35. After an ischemic event, disruptive changes in the healthy myocardium may gradually develop and may ultimately turn into fibrotic scar. While these structural changes have been described by conventional imagin...

    Authors: Martin J. Willemink, Akos Varga-Szemes, U. Joseph Schoepf, Marina Codari, Koen Nieman, Dominik Fleischmann and Domenico Mastrodicasa

    Citation: European Radiology Experimental 2021 5:12

    Content type: Narrative review

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  36. Body composition is associated with survival outcome in oncological patients, but it is not routinely calculated. Manual segmentation of subcutaneous adipose tissue (SAT) and muscle is time-consuming and there...

    Authors: Pablo Borrelli, Reza Kaboteh, Olof Enqvist, Johannes Ulén, Elin Trägårdh, Henrik Kjölhede and Lars Edenbrandt

    Citation: European Radiology Experimental 2021 5:11

    Content type: Original article

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  37. No chemotherapeutic agents have been standardised for transarterial chemoembolisation (TACE). In particular, doxorubicin has no defined optimal dosage in TACE procedures. We compared low versus currently used dos...

    Authors: Ahmed A. Bessar, Ahmed Farag, Sameh M. Abdel Monem, Fady M. Wadea, Shady E. Shaker, Mahmoud Ahmed Ebada and Manar A. Bessar

    Citation: European Radiology Experimental 2021 5:10

    Content type: Original article

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  38. Rib fractures are associated with considerable morbidity and mortality. Surgical stabilization of rib fractures (SSRF) can be performed to mitigate complications. Sarcopenia is in general known to be associate...

    Authors: Derrick A. Doolittle, Matthew C. Hernandez, Francis I. Baffour, Michael R. Moynagh, Naoki Takahashi, Adam T. Froemming, Katrina N. Glazebrook and Brian D. Kim

    Citation: European Radiology Experimental 2021 5:9

    Content type: Original article

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  39. Colonic manometry is the current reference standard for assessing colonic neuromuscular function in children with intractable functional constipation (FC). Recently, cine magnetic resonance imaging (cine-MRI) ...

    Authors: M. H. Vriesman, C. S. de Jonge, S. Kuizenga-Wessel, B. Adler, A. Menys, A. J. Nederveen, J. Stoker, M. A. Benninga and C. Di Lorenzo

    Citation: European Radiology Experimental 2021 5:8

    Content type: Original article

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  40. We aimed to train and test a deep learning classifier to support the diagnosis of coronavirus disease 2019 (COVID-19) using chest x-ray (CXR) on a cohort of subjects from two hospitals in Lombardy, Italy.

    Authors: Isabella Castiglioni, Davide Ippolito, Matteo Interlenghi, Caterina Beatrice Monti, Christian Salvatore, Simone Schiaffino, Annalisa Polidori, Davide Gandola, Cristina Messa and Francesco Sardanelli

    Citation: European Radiology Experimental 2021 5:7

    Content type: Original article

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  41. Grating-based x-ray dark-field and phase-contrast imaging allow extracting information about refraction and small-angle scatter, beyond conventional attenuation. A step towards clinical translation has recentl...

    Authors: Jana Andrejewski, Fabio De Marco, Konstantin Willer, Wolfgang Noichl, Alex Gustschin, Thomas Koehler, Pascal Meyer, Fabian Kriner, Florian Fischer, Christian Braun, Alexander A. Fingerle, Julia Herzen, Franz Pfeiffer and Daniela Pfeiffer

    Citation: European Radiology Experimental 2021 5:6

    Content type: Original article

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  42. Average Hausdorff distance is a widely used performance measure to calculate the distance between two point sets. In medical image segmentation, it is used to compare ground truth images with segmentations all...

    Authors: Orhun Utku Aydin, Abdel Aziz Taha, Adam Hilbert, Ahmed A. Khalil, Ivana Galinovic, Jochen B. Fiebach, Dietmar Frey and Vince Istvan Madai

    Citation: European Radiology Experimental 2021 5:4

    Content type: Methodology

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  43. To evaluate robustness and repeatability of magnetic resonance imaging (MRI) texture features in water and tissue phantom test-retest study.

    Authors: Joshua Shur, Matthew Blackledge, James D’Arcy, David J. Collins, Maria Bali, Martin O’Leach and Dow-Mu Koh

    Citation: European Radiology Experimental 2021 5:2

    Content type: Original article

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  44. This review describes a cellular adaptive stress signalling roadmap connecting the 1H magnetic resonance spectroscopy (MRS) total choline peak at 3.2 ppm (tCho) to cancer response after targeted therapy (TT). Rec...

    Authors: Egidio Iorio, Franca Podo, Martin O. Leach, Jason Koutcher, Francis G. Blankenberg and Joseph F. Norfray

    Citation: European Radiology Experimental 2021 5:5

    Content type: Narrative review

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  45. The detection and assessment of cerebral lesions and traumatic brain injuries are of particular interest in forensic investigations in order to differentiate between natural and traumatic deaths and to reconst...

    Authors: Dominic Gascho, Niklaus Zoelch, Stefan Sommer, Carlo Tappero, Michael J. Thali and Eva Deininger-Czermak

    Citation: European Radiology Experimental 2021 5:3

    Content type: Technical note

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  46. Multidetector row computed tomography (CT) scanners perform dynamic scanning and have a wide scan range. Time-resolved three-dimensional CT (i.e., 4D CT) has recently enabled visualization of flow in neurovascula...

    Authors: Ken Kageyama, Akira Yamamoto, Atsushi Jogo, Shinichiro Izuta, Daisuke Himoto, Akihiko Kakimi, Etsuji Sohgawa and Yukio Miki

    Citation: European Radiology Experimental 2021 5:1

    Content type: Technical note

    Published on:

  47. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Bruno Paun, Daniel García Leon, Alex Claveria Cabello, Roso Mares Pages, Elena de la Calle Vargas, Paola Contreras Muñoz, Vanessa Venegas Garcia, Joan Castell-Conesa, Mario Marotta Baleriola and Jose Raul Herance Camacho

    Citation: European Radiology Experimental 2020 4:69

    Content type: Correction

    Published on:

    The original article was published in European Radiology Experimental 2020 4:33

  48. Integration of imaging and clinical parameters could improve the stratification of COVID-19 patients on emergency department (ED) admission. We aimed to assess the extent of COVID-19 pulmonary abnormalities on...

    Authors: Cristian Giuseppe Monaco, Federico Zaottini, Simone Schiaffino, Alessandro Villa, Gianmarco Della Pepa, Luca Alessandro Carbonaro, Laura Menicagli, Andrea Cozzi, Serena Carriero, Francesco Arpaia, Giovanni Di Leo, Davide Astengo, Ilan Rosenberg and Francesco Sardanelli

    Citation: European Radiology Experimental 2020 4:68

    Content type: Original article

    Published on:

    The Correction to this article has been published in European Radiology Experimental 2021 5:17

  49. Transjugular intrahepatic portosystemic shunt (TIPS) is currently indicated as first therapeutic option in the main complications of portal hypertension, including bleeding gastroesophageal varices and refract...

    Authors: Massimo Venturini, Luigi Augello, Carolina Lanza, Marco Curti, Andrea Coppola, Filippo Piacentino and Francesco De Cobelli

    Citation: European Radiology Experimental 2020 4:67

    Content type: Technical note

    Published on:

  50. Traumatic head injuries are one of the leading causes of emergency worldwide due to their frequency and associated morbidity. The circumstances of their onset are often sports activities or road accidents. Num...

    Authors: Yannick Distriquin, Jean-Marc Vital and Bruno Ella

    Citation: European Radiology Experimental 2020 4:66

    Content type: Narrative review

    Published on:

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