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  1. Data shortage is a common challenge in developing computer-aided diagnosis systems. We developed a generative adversarial network (GAN) model to generate synthetic lung lesions mimicking ground glass nodules (...

    Authors: Zhixiang Wang, Zhen Zhang, Ying Feng, Lizza E. L. Hendriks, Razvan L. Miclea, Hester Gietema, Janna Schoenmaekers, Andre Dekker, Leonard Wee and Alberto Traverso
    Citation: European Radiology Experimental 2022 6:59
    Content type: Original article Published on:

  2. Magnetic resonance imaging (MRI) can be used to target tumour components in biopsy procedures, while the ability to precisely correlate histology and MRI signal is crucial for imaging biomarker validation. Roboti...

    Authors: Edward W. Johnston, Nicos Fotiadis, Craig Cummings, Jodie Basso, Toby Tyne, Joost Lameijer, Christina Messiou, Dow-Mu Koh and Jessica M. Winfield
    Citation: European Radiology Experimental 2022 6:55
    Content type: Original article Published on:

  3. Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that can lead to cirrhosis and hepatic decompensation. However, predicting future outcomes in patients with PSC is challenging. Our a...

    Authors: Yashbir Singh, William A. Jons, John E. Eaton, Mette Vesterhus, Tom Karlsen, Ida Bjoerk, Andreas Abildgaard, Kristin Kaasen Jorgensen, Trine Folseraas, Derek Little, Aliya F. Gulamhusein, Kosta Petrovic, Anne Negard, Gian Marco Conte, Joseph D. Sobek, Jaidip Jagtap…
    Citation: European Radiology Experimental 2022 6:58
    Content type: Original article Published on:

  4. The cerebellum is involved in hyperactivity, fear, and anxiety disorders that could be induced by whole-brain irradiation (WBI). However, whether cerebellar irradiation alone (CIA) could induce these disorders...

    Authors: Yafeng Wang, Cuicui Xie, Yiran Xu, Yaodong Zhang, Changlian Zhu and Kai Zhou
    Citation: European Radiology Experimental 2022 6:57
    Content type: Original article Published on:

  5. NAVIGATOR is an Italian regional project boosting precision medicine in oncology with the aim of making it more predictive, preventive, and personalised by advancing translational research based on quantitativ...

    Authors: Rita Borgheresi, Andrea Barucci, Sara Colantonio, Gayane Aghakhanyan, Massimiliano Assante, Elena Bertelli, Emanuele Carlini, Roberto Carpi, Claudia Caudai, Diletta Cavallero, Dania Cioni, Roberto Cirillo, Valentina Colcelli, Andrea Dell’Amico, Domnico Di Gangi, Paola Anna Erba…
    Citation: European Radiology Experimental 2022 6:53
    Content type: Guideline/Position paper Published on:

  6. A new 72-channel receive array coil and sensitivity encoding, compressed (C-SENSE) and noncompressed (SENSE), were investigated to decrease the number of breath-holds (BHs) for cardiac magnetic resonance (CMR).

    Authors: Hugo Klarenberg, Mark Gosselink, Bram F. Coolen, Tim Leiner, Aart J. Nederveen, Adrianus J. Bakermans, Hildo J. Lamb, S. Matthijs Boekholdt, Martijn Froeling and Gustav J. Strijkers
    Citation: European Radiology Experimental 2022 6:54
    Content type: Original article Published on:

  8. To investigate the detection capabilities of myocardial perfusion defects of dual-energy computed tomography (CT) technology using time-resolved iodine-based maps for functional assessment of coronary stenosis...

    Authors: Johannes Hammel, Lorenz Birnbacher, Marcus R. Makowski, Franz Pfeiffer and Daniela Pfeiffer
    Citation: European Radiology Experimental 2022 6:51
    Content type: Original article Published on:

  9. We annually monitored stable compensated cirrhosis (CC) patients to evaluate serial variation in blood serum, liver stiffness, and multiparametric magnetic resonance imaging (mpMRI) measures to provide referen...

    Authors: Christopher R. Bradley, Eleanor F. Cox, Naaventhan Palaniyappan, Guruprasad P. Aithal, Susan T. Francis and Indra Neil Guha
    Citation: European Radiology Experimental 2022 6:52
    Content type: Original article Published on:

  10. The detection of peritoneal carcinomatosis in patients with ovarian cancer is crucial to establish the correct therapeutic planning (debulking surgery versus neoadjuvant chemotherapy).

    Authors: Giada Zorzetto, Andrea Coppola, Valeria Molinelli, Maria Gloria Angeretti, Jvan Casarin, Federico Fontana, Filippo Piacentino, Giulio Carcano, Fabio Ghezzi and Massimo Venturini
    Citation: European Radiology Experimental 2022 6:45
    Content type: Hypothesis Published on:

  11. The use of facemasks is one of the consequences of the coronavirus disease 2019 (COVID-19) pandemic. We used resting-state functional magnetic resonance imaging (fMRI) to search for subtle changes in brain fun...

    Authors: Sven Haller, Marie-Louise Montandon, Cristelle Rodriguez and Panteleimon Giannakopoulos
    Citation: European Radiology Experimental 2022 6:50
    Content type: Original article Published on:

  12. The aim of this study was to investigate the role of the lipid peak derived from 1H magnetic resonance (MR) spectroscopy in assessing cervical cancer prognosis, particularly in assessing response to neoadjuvant c...

    Authors: Miriam Dolciami, Rossella Canese, Claudia Testa, Angelina Pernazza, Giusi Santangelo, Innocenza Palaia, Carlo Della Rocca, Carlo Catalano and Lucia Manganaro
    Citation: European Radiology Experimental 2022 6:47
    Content type: Original article Published on:

  13. To evaluate simplified intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) for differentiating malignant versus benign breast lesions as (i) stand-alone tool and (ii) add-on to dynamic contrast-e...

    Authors: Petra Mürtz, Mark Tsesarskiy, Alois M. Sprinkart, Wolfgang Block, Oleksandr Savchenko, Julian A. Luetkens, Ulrike Attenberger and Claus C. Pieper
    Citation: European Radiology Experimental 2022 6:48
    Content type: Original article Published on:

  14. To validate the k-adaptive-t autocalibrating reconstruction for Cartesian sampling (kat-ARC), an exclusive sparse reconstruction technique for four-dimensional (4D) flow cardiac magnetic resonance (CMR) using ...

    Authors: Hosamadin Assadi, Bhalraam Uthayachandran, Rui Li, James Wardley, Tha H. Nyi, Ciaran Grafton-Clarke, Andrew J. Swift, Ana Beatriz Solana, Jean-Paul Aben, Kurian Thampi, David Hewson, Chris Sawh, Richard Greenwood, Marina Hughes, Bahman Kasmai, Liang Zhong…
    Citation: European Radiology Experimental 2022 6:46
    Content type: Original article Published on:

  15. We evaluated the role of radiomics applied to contrast-enhanced computed tomography (CT) in the detection of lymph node (LN) metastases in patients with known lung cancer compared to 18F-fluorodeoxyglucose positr...

    Authors: Boris Gorodetski, Philipp Hendrik Becker, Alexander Daniel Jacques Baur, Alexander Hartenstein, Julian Manuel Michael Rogasch, Christian Furth, Holger Amthauer, Bernd Hamm, Marcus Makowski and Tobias Penzkofer
    Citation: European Radiology Experimental 2022 6:44
    Content type: Original article Published on:

  16. In radiomics studies, differences in the volume of interest (VOI) are often inevitable and may confound the extracted features. We aimed to correct this confounding effect of VOI variability by applying parame...

    Authors: Laura J. Jensen, Damon Kim, Thomas Elgeti, Ingo G. Steffen, Lars-Arne Schaafs, Bernd Hamm and Sebastian N. Nagel
    Citation: European Radiology Experimental 2022 6:43
    Content type: Original article Published on:

  17. Though abnormal iron deposition has been reported in specific brain regions in multiple sclerosis (MS), no data exist about whether the overall quantity of iron in the brain is altered or not. We aimed to dete...

    Authors: Eman Hamdy, Aya Abdel Galeel, Ismail Ramadan, Dina Gaber, Haytham Mustafa and Jaidaa Mekky
    Citation: European Radiology Experimental 2022 6:49
    Content type: Original article Published on:

  18. Malignancy of lipomatous soft-tissue tumours diagnosis is suspected on magnetic resonance imaging (MRI) and requires a biopsy. The aim of this study is to compare the performances of MRI radiomic machine learn...

    Authors: Guillaume Fradet, Reina Ayde, Hugo Bottois, Mohamed El Harchaoui, Wassef Khaled, Jean-Luc Drapé, Frank Pilleul, Amine Bouhamama, Olivier Beuf and Benjamin Leporq
    Citation: European Radiology Experimental 2022 6:41
    Content type: Original article Published on:

  20. Acoustic noise in magnetic resonance imaging (MRI) negatively impacts patients. We assessed a silent gradient coil switched at 20 kHz combined with a T1-weighted magnetisation prepared rapid gradient-echo (MPRAGE...

    Authors: Sarah M. Jacobs, Edwin Versteeg, Anja G. van der Kolk, Leonie N. C. Visser, Ícaro A. F. Oliveira, Emiel van Maren, Dennis W. J. Klomp and Jeroen C. W. Siero
    Citation: European Radiology Experimental 2022 6:36
    Content type: Original article Published on:

  21. Computed tomography perfusion imaging (CTPI) by repeated scanning has clinical relevance but implies relatively high radiation exposure. We present a method to measure perfusion from two CT scan phases only, c...

    Authors: Massimo Cressoni, Andrea Cozzi, Simone Schiaffino, Paolo Cadringher, Paolo Vitali, Gianpaolo Basso, Davide Ippolito and Francesco Sardanelli
    Citation: European Radiology Experimental 2022 6:37
    Content type: Original article Published on:

  22. Magnetic resonance imaging (MRI) is an important part of breast cancer diagnosis and multimodal workup. It provides unsurpassed soft tissue contrast to analyse the underlying pathophysiology, and it is adopted...

    Authors: Matthias Dietzel, Rubina Manuela Trimboli, Moreno Zanardo, Rüdiger Schultz-Wendtland, Michael Uder, Paola Clauser, Francesco Sardanelli and Pascal A. T. Baltzer
    Citation: European Radiology Experimental 2022 6:42
    Content type: Narrative review Published on:

  23. The increasingly widespread use of computed tomography (CT) has increased the number of detected lung lesions, which are then subjected to needle biopsy to obtain histopathological diagnosis. Obtaining high-qu...

    Authors: Marco Curti, Federico Fontana, Filippo Piacentino, Christian Ossola, Andrea Coppola, Giulio Carcano and Massimo Venturini
    Citation: European Radiology Experimental 2022 6:34
    Content type: Hypothesis Published on:

  24. Breast cancer (BC) includes different pathological and molecular subtypes. This study aimed to investigate whether multiparametric magnetic resonance imaging (mpMRI) could reliably predict the molecular status...

    Authors: Francesca Galati, Veronica Rizzo, Giuliana Moffa, Claudia Caramanico, Endi Kripa, Bruna Cerbelli, Giulia D’Amati and Federica Pediconi
    Citation: European Radiology Experimental 2022 6:39
    Content type: Original article Published on:

  25. Artificial intelligence (AI) for prostate magnetic resonance imaging (MRI) is starting to play a clinical role for prostate cancer (PCa) patients. AI-assisted reading is feasible, allowing workflow reduction. ...

    Authors: Mohammed R. S. Sunoqrot, Anindo Saha, Matin Hosseinzadeh, Mattijs Elschot and Henkjan Huisman
    Citation: European Radiology Experimental 2022 6:35
    Content type: Narrative review Published on:

  26. The advent of precision medicine, increasing clinical needs, and imaging availability among many other factors in the prostate cancer diagnostic pathway has engendered the utilization of artificial intelligenc...

    Authors: Mason J. Belue and Baris Turkbey
    Citation: European Radiology Experimental 2022 6:33
    Content type: Narrative review Published on:

  27. As bone microstructure is known to impact bone strength, the aim of this in vitro study was to evaluate if the emerging photon-counting detector computed tomography (PCD-CT) technique may be used for measurements...

    Authors: Benjamin Klintström, Lilian Henriksson, Rodrigo Moreno, Alexandr Malusek, Örjan Smedby, Mischa Woisetschläger and Eva Klintström
    Citation: European Radiology Experimental 2022 6:31
    Content type: Original article Published on:

  28. Fatty infiltration of the paraspinal muscles may play a role in pain and disability in lumbar spinal stenosis. We assessed the reliability and association with clinical symptoms of a method for assessing fatty...

    Authors: Hasan Banitalebi, Jørn Aaen, Kjersti Storheim, Anne Negård, Tor Åge Myklebust, Margreth Grotle, Christian Hellum, Ansgar Espeland, Masoud Anvar, Kari Indrekvam, Clemens Weber, Jens Ivar Brox, Helena Brisby and Erland Hermansen
    Citation: European Radiology Experimental 2022 6:38
    Content type: Original article Published on:

  29. We investigated whether features derived from texture analysis (TA) can distinguish breast density (BD) in spiral photon-counting breast computed tomography (PC-BCT).

    Authors: Anna Landsmann, Carlotta Ruppert, Jann Wieler, Patryk Hejduk, Alexander Ciritsis, Karol Borkowski, Moritz C. Wurnig, Cristina Rossi and Andreas Boss
    Citation: European Radiology Experimental 2022 6:30
    Content type: Original article Published on:

  30. Local blood flow affects vascular disease and outcomes of endovascular treatment, but quantifying it is challenging, especially inside stents. We assessed the feasibility of blood flow quantification in native...

    Authors: Majorie van Helvert, Stefan Engelhard, Jason Voorneveld, Marije van der Vee, Johan G. Bosch, Michel Versluis, Erik Groot Jebbink and Michel M. P. J. Reijnen
    Citation: European Radiology Experimental 2022 6:32
    Content type: Original article Published on:

  31. We retrospectively evaluated safety and performance of magnetic seed localisation of nonpalpable breast lesions.

    Authors: Antonella Petrillo, Raimondo Di Giacomo, Emanuela Esposito, Paolo Vallone, Sergio Venanzio Setola, Mauro Mattace Raso, Vincenza Granata, Maria Luisa Barretta, Claudio Siani, Chiara Rinaldo, Ivana Donzelli, Ugo Marone, Maria Teresa Melucci, Alfredo Fucito, Ruggero Saponara, Maurizio Di Bonito…
    Citation: European Radiology Experimental 2022 6:28
    Content type: Original article Published on:

  32. A huge amount of imaging data is becoming available worldwide and an incredible range of possible improvements can be provided by artificial intelligence algorithms in clinical care for diagnosis and decision ...

    Authors: Haridimos Kondylakis, Esther Ciarrocchi, Leonor Cerda-Alberich, Ioanna Chouvarda, Lauren A. Fromont, Jose Manuel Garcia-Aznar, Varvara Kalokyri, Alexandra Kosvyra, Dawn Walker, Guang Yang and Emanuele Neri
    Citation: European Radiology Experimental 2022 6:29
    Content type: Guideline/Position paper Published on:

  33. Since its first description 25 years ago, color Doppler twinkling has been a compelling ultrasound feature in diagnosing urinary stones. While the fundamental cause of twinkling remains elusive, the distinctiv...

    Authors: Christine U. Lee, Matthew W. Urban, A. Lee Miller II, Susheil Uthamaraj, James W. Jakub, Gina K. Hesley, Benjamin G. Wood, Nathan J. Brinkman, James L. Herrick, Nicholas B. Larson, Michael J. Yaszemski and James F. Greenleaf
    Citation: European Radiology Experimental 2022 6:26
    Content type: Technical note Published on:

  34. In prostate cancer (PCa), the use of new radiopharmaceuticals has improved the accuracy of diagnosis and staging, refined surveillance strategies, and introduced specific and personalized radioreceptor therapi...

    Authors: Virginia Liberini, Riccardo Laudicella, Michele Balma, Daniele G. Nicolotti, Ambra Buschiazzo, Serena Grimaldi, Leda Lorenzon, Andrea Bianchi, Simona Peano, Tommaso Vincenzo Bartolotta, Mohsen Farsad, Sergio Baldari, Irene A. Burger, Martin W. Huellner, Alberto Papaleo and Désirée Deandreis
    Citation: European Radiology Experimental 2022 6:27
    Content type: Systematic review Published on:

  35. In multiple sclerosis, the correlation between white matter lesion volumes (LV) and expanded disability status scale (EDSS) is at best moderate, leading to the “clinico-radiological paradox”, influenced by man...

    Authors: Caterina Lapucci, Simona Schiavi, Alessio Signori, Elvira Sbragia, Giulia Bommarito, Maria Cellerino, Antonio Uccelli, Matilde Inglese, Luca Roccatagliata and Matteo Pardini
    Citation: European Radiology Experimental 2022 6:23
    Content type: Brief report Published on:

  36. Estimating the required sample size is crucial when developing and validating clinical prediction models. However, there is no consensus about how to determine the sample size in such a setting. Here, the goal...

    Authors: Carlos Baeza-Delgado, Leonor Cerdá Alberich, José Miguel Carot-Sierra, Diana Veiga-Canuto, Blanca Martínez de las Heras, Ben Raza and Luis Martí-Bonmatí
    Citation: European Radiology Experimental 2022 6:22
    Content type: Original article Published on:

  37. Our aim was to evaluate the reproducibility of epicardial adipose tissue (EAT) volume, measured on scans performed using an open-bore magnetic resonance scanner.

    Authors: Francesco Secchi, Carmela Asteria, Caterina B. Monti, Alexis Elias Malavazos, Davide Capra, Marco Alì, Cecilia L. A. Giassi, Simona Francesconi, Sara Basilico, Alessandro Giovanelli, Lelio Morricone and Francesco Sardanelli
    Citation: European Radiology Experimental 2022 6:25
    Content type: Original article Published on:

  38. The aim of this animal study was to compare the fluoroscopic image quality (IQ) and radiation dose between a tantalum (Ta)-specific contrast-to-noise ratio-driven exposure control (Ta-CEC) and a detector dose-...

    Authors: Thomas Werncke, Timo Christian Meine, Jan B. Hinrichs, Sabine K. Maschke, Lena Sophie Becker, Inga Brüsch, Regina Rumpel, Frank K. Wacker and Bernhard C. Meyer
    Citation: European Radiology Experimental 2022 6:24
    Content type: Original article Published on:

  39. The use of a pocked-sized, wireless-Bluetooth ultrasound portable system with display images presented on a tablet facilitated the work of our radiologists during the first wave of coronavirus disease 2019 (CO...

    Authors: Christian Ossola, Filippo Piacentino, Federico Fontana, Marco Curti, Giada Zorzetto, Andrea Coppola, Giulio Carcano and Massimo Venturini
    Citation: European Radiology Experimental 2022 6:20
    Content type: Hypothesis Published on:

  40. Pathological complete response after neoadjuvant chemoradiotherapy in locally advanced rectal cancer (LARC) is achieved in 15–30% of cases. Our aim was to implement and externally validate a magnetic resonance...

    Authors: Arianna Defeudis, Simone Mazzetti, Jovana Panic, Monica Micilotta, Lorenzo Vassallo, Giuliana Giannetto, Marco Gatti, Riccardo Faletti, Stefano Cirillo, Daniele Regge and Valentina Giannini
    Citation: European Radiology Experimental 2022 6:19
    Content type: Original article Published on:

  41. Radiofrequency ablation (RFA) is a minimally invasive technique used for the treatment of neoplasms, with a growing interest in the treatment of bone tumours. However, the lack of data concerning the size of t...

    Authors: Ricardo Rivas Loya, Paul C. Jutte, Thomas C. Kwee and Peter M. A. van Ooijen
    Citation: European Radiology Experimental 2022 6:21
    Content type: Original article Published on:

  42. Despite the new lymphatic imaging methods, there is still a need for a straightforward method of detecting lymphatic abnormalities. Our goal was to investigate the feasibility of applying a contrast enhanced u...

    Authors: Olli Lahtinen, Ritva Vanninen and Suvi Rautiainen
    Citation: European Radiology Experimental 2022 6:18
    Content type: Original article Published on:

  43. While computed tomography (CT) exams are the major cause of medical exposure to ionising radiation, the radiation-induced risks must be documented. We investigated the impact of the cellular models and individ...

    Authors: Clément Devic, Larry Bodgi, Laurène Sonzogni, Frank Pilleul, Hervé Ribot, Charlotte De Charry, François Le Moigne, Didier Paul, Fanny Carbillet, Mélodie Munier and Nicolas Foray
    Citation: European Radiology Experimental 2022 6:17
    Content type: Original article Published on:

  44. A negative oral contrast agent (OCA) has been long sought for, to better delineate the bowel and visualise surrounding structures. Lumentin® 44 (L44) is a new OCA formulated to fill the entire small bowel. The...

    Authors: Peter Leander, Georgios Stathis, Lucia Casal-Dujat, Karolina Boman, Ingvar Adnerhill, Jan Marsal, Olof Böök and Thomas Fork
    Citation: European Radiology Experimental 2022 6:15
    Content type: Original article Published on:

  46. While computed tomography (CT) exams are the major cause of medical exposure to ionising radiation, there is increasing evidence that the potential radiation-induced risks must be documented. We investigated t...

    Authors: Clément Devic, Larry Bodgi, Laurène Sonzogni, Frank Pilleul, Hervé Ribot, Charlotte De Charry, François Le Moigne, Didier Paul, Fanny Carbillet, Mélodie Munier and Nicolas Foray
    Citation: European Radiology Experimental 2022 6:14
    Content type: Original article Published on:

  47. We evaluated the accuracy, safety, and feasibility of a computed tomography (CT)-guided robotic assistance system for percutaneous needle placement in the kidney.

    Authors: Thierry de Baere, Charles Roux, Guillaume Noel, Alexandre Delpla, Frederic Deschamps, Eloi Varin and Lambros Tselikas
    Citation: European Radiology Experimental 2022 6:13
    Content type: Original article Published on:

  48. Magnetic resonance imaging (MRI) is currently considered a safe imaging technique because, unlike computed tomography, MRI does not expose patients to ionising radiation. However, conflicting literature report...

    Authors: Cecile Herate, Patricia Brochard, Florent De Vathaire, Michelle Ricoul, Bernadette Martins, Laurence Laurier, Jean-Robert Deverre, Bertrand Thirion, Lucie Hertz-Pannier and Laure Sabatier
    Citation: European Radiology Experimental 2022 6:12
    Content type: Original article Published on:

  49. Spirometry and conventional chest x-ray have limitations in investigating early emphysema, while computed tomography, the reference imaging method in this context, is not part of routine patient care due to it...

    Authors: Gregor S. Zimmermann, Alexander A. Fingerle, Bernhard Renger, Karl-Ludwig Laugwitz, Hubert Hautmann, Andreas Sauter, Felix Meurer, Florian Tilman Gassert, Jannis Bodden, Christina Müller-Leisse, Martin Renz, Ernst J. Rummeny, Marcus R. Makowski, Konstantin Willer, Wolfgang Noichl, Fabio De Marco…
    Citation: European Radiology Experimental 2022 6:9
    Content type: Original article Published on:

  50. Passive paramagnetic markers on magnetic resonance imaging (MRI)-compatible endovascular devices induce susceptibility artifacts, enabling MRI-visibility and real-time MRI-guidance. Optimised visibility is cru...

    Authors: Han Nijsink, Christiaan G. Overduin, Patrick Brand, Sytse F. De Jong, Paul J. A. Borm, Michiel C. Warlé and Jurgen J. Fütterer
    Citation: European Radiology Experimental 2022 6:11
    Content type: Original article Published on:
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