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  1. Finite element modeling is a precious tool for the investigation of the biomechanics of the musculoskeletal system. A key element for the development of anatomically accurate, state-of-the art finite element m...

    Authors: Fabio Galbusera, Andrea Cina, Matteo Panico, Domenico Albano and Carmelo Messina

    Citation: European Radiology Experimental 2020 4:49

    Content type: Narrative review

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  2. Ultra-high field magnetic resonance imaging (UHF-MRI) provides important diagnostic improvements in musculoskeletal imaging. The higher signal-to-noise ratio leads to higher spatial and temporal resolution whi...

    Authors: Giacomo Aringhieri, Virna Zampa and Michela Tosetti

    Citation: European Radiology Experimental 2020 4:48

    Content type: Narrative review

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  3. Our aim was to compare the diagnostic performance of digital breast tomosynthesis (DBT)-galactography with that of full-field digital (FFD)-galactography for detecting intraductal breast lesions using an intra...

    Authors: Marco Moschetta, Vincenzo De Ruvo, Angelica Drago, Nicoletta Troiano, Simona Paolicelli, Giuseppe Rubini, Amato Antonio Stabile Ianora and Michele Telegrafo

    Citation: European Radiology Experimental 2020 4:40

    Content type: Original article

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  4. We investigated a recently proposed multiexponential (Mexp) fitting method applied to T2 relaxometry magnetic resonance imaging (MRI) data of benign and malignant adipocytic tumours and healthy subcutaneous fa...

    Authors: Katerina Nikiforaki, Georgios S. Ioannidis, Eleni Lagoudaki, Georgios H. Manikis, Eelco de Bree, Apostolos Karantanas, Thomas G. Maris and Kostas Marias

    Citation: European Radiology Experimental 2020 4:45

    Content type: Original article

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  5. A challenge in imaging research is a diagnostic classification of study participants. We hypothesised that a structured approach would be efficient and that classification by medical students, residents, and a...

    Authors: Tjitske S. R. van Engelen, Maadrika M. N. P. Kanglie, Inge A. H. van den Berk, Merel L. J. Bouwman, Hind J. M. Suhooli, Sascha L. Heckert, Jaap Stoker, Patrick M. M. Bossuyt and Jan M. Prins

    Citation: European Radiology Experimental 2020 4:44

    Content type: Original article

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  6. In limestone caves, environmental processes often cause alterations of human or animal skeletal remains, complicating classical analytical methods. Exemplary, a proximal femoral skeletal fragment, enclosed by ...

    Authors: Patrick E. Eppenberger, Mislav Čavka, Siniša Radović, Dalibor Paar, Nenad Buzjak, James C. M. Ahern, Philipp Biedermann, Philipp Gruber, Mario Novak and Ivor Janković

    Citation: European Radiology Experimental 2020 4:41

    Content type: Technical note

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  7. To propose a practical and simple method to individually evaluate the average absorbed dose for digital breast tomosynthesis.

    Authors: Antonio C. Traino, Patrizio Barca, Rocco Lamastra, Raffaele M. Tucciariello, Chiara Sottocornola, Carolina Marini, Giacomo Aringhieri, Davide Caramella and Maria E. Fantacci

    Citation: European Radiology Experimental 2020 4:38

    Content type: Original article

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  8. The in situ classification of bullets is of interest in forensic investigations when the bullet cannot be removed. Although computed tomography (CT) is usually performed on shooting victims, visual assessment, or...

    Authors: Dominic Gascho, Niklaus Zoelch, Henning Richter, Alexander Buehlmann, Philipp Wyss, Michael J. Thali and Sarah Schaerli

    Citation: European Radiology Experimental 2020 4:43

    Content type: Original article

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  9. More than 1,200 active or recruiting clinical trials for novel coronavirus disease 2019 (COVID-19) treatments and vaccines are registered. Many drugs have shown promise for treatment of COVID-19. Nevertheless,...

    Authors: Mohamed M. A. Zaitoun, Mohammad Abd Alkhalik Basha and Ali Hassan Elmokadem

    Citation: European Radiology Experimental 2020 4:42

    Content type: Hypothesis

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  10. Time-resolved three-dimensional digital subtraction angiography (4D-DSA) can be used to quantify blood velocity. Contrast pulsatility, a major discriminant on 4D-DSA, is yet to be optimized. We investigated th...

    Authors: Ece Meram, Gabe Shaughnessy, Colin Longhurst, Carson Hoffman, Martin Wagner, Charles A. Mistretta, Michael A. Speidel and Paul F. Laeseke

    Citation: European Radiology Experimental 2020 4:37

    Content type: Original article

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  11. Computed tomography (CT) enables quantification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, helping in outcome prediction.

    Authors: João Matos, Francesco Paparo, Ilaria Mussetto, Lorenzo Bacigalupo, Alessio Veneziano, Silvia Perugin Bernardi, Ennio Biscaldi, Enrico Melani, Giancarlo Antonucci, Paolo Cremonesi, Marco Lattuada, Alberto Pilotto, Emanuele Pontali and Gian Andrea Rollandi

    Citation: European Radiology Experimental 2020 4:39

    Content type: Original article

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  12. This review provides an overview of the currently available computed tomography (CT) techniques for myocardial tissue characterization in ischemic heart disease, including CT perfusion and late iodine enhancem...

    Authors: M. van Assen, M. Vonder, G. J. Pelgrim, P. L. Von Knebel Doeberitz and R. Vliegenthart

    Citation: European Radiology Experimental 2020 4:36

    Content type: Narrative review

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  13. We assessed confidence in visualization of markers within metastatic axillary lymph nodes (LNs) on magnetic resonance imaging (MRI), which were placed post-ultrasound (US)-guided biopsy.

    Authors: Naziya Samreen, Asha A. Bhatt, Kalie Adler, Shannon Zingula and Katrina N. Glazebrook

    Citation: European Radiology Experimental 2020 4:34

    Content type: Original article

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  14. We investigated the composition of the gluteal (gluteus maximus, medius, and minimus) and quadriceps (rectus femoris, vastus lateralis, medialis, and intermedius) muscle groups and its associations with femora...

    Authors: Michael Dieckmeyer, Florian Zoffl, Lioba Grundl, Stephanie Inhuber, Sarah Schlaeger, Egon Burian, Claus Zimmer, Jan S. Kirschke, Dimitrios C. Karampinos, Thomas Baum and Nico Sollmann

    Citation: European Radiology Experimental 2020 4:35

    Content type: Original article

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  15. Calvaria skin has a reduced thickness, and its initial damage produced by irradiation was scarcely reported. We aimed to identify the initial effects of x-ray irradiation in the rat calvaria skin.

    Authors: Matheus da Silva Santin, José Koehler, Danilo Massuia Rocha, Camila Audrey dos Reis, Nadia Fayez Omar, Yasmin Fidler, Maria Albertina de Miranda Soares and José Rosa Gomes

    Citation: European Radiology Experimental 2020 4:32

    Content type: Original article

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  16. Skeletal muscle injury characterisation during healing supports trauma prognosis. Given the potential interest of computed tomography (CT) in muscle diseases and lack of in vivo CT methodology to image skeletal m...

    Authors: Bruno Paun, Daniel García Leon, Alex Claveria Cabello, Roso Mares Pages, Elena de la Calle Vargas, Paola Contreras Muñoz, Vanessa Venegas Garcia, Joan Castell-Conesa, Mario Marotta Baleriola and Jose Raul Herance Camacho

    Citation: European Radiology Experimental 2020 4:33

    Content type: Original article

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  17. Compared to histology-based methods, imaging can reduce animal usage in preclinical studies. However, availability of dedicated scanners is limited. We evaluated clinical computed tomography (CT) and magnetic ...

    Authors: Judith E. Spiro, Miriam Rinneburger, Dennis M. Hedderich, Mladen Jokic, Hans Christian Reinhardt, David Maintz, Moritz Palmowski and Thorsten Persigehl

    Citation: European Radiology Experimental 2020 4:31

    Content type: Original article

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  18. Microspheres loaded with radioactive 166Ho (166Ho-MS) are novel particles for radioembolisation and intratumoural treatment. Because of the limited penetration of β radiation, quantitative imaging of microsphere ...

    Authors: R. C. Bakker, R. Bastiaannet, S. A. van Nimwegen, A. D. Barten-van Rijbroek, R. J. J. Van Es, A. J. W. P. Rosenberg, H. W. A. M. de Jong, M. G. E. H. Lam and J. F. W. Nijsen

    Citation: European Radiology Experimental 2020 4:29

    Content type: Original article

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  19. The inverse Laplace transform (ILT) is the most widely used method for T2 relaxometry data analysis. This study examines the qualitative agreement of ILT and a proposed multiexponential (Mexp method) regarding...

    Authors: Georgios S. Ioannidis, Katerina Nikiforaki, Georgios Kalaitzakis, Apostolos Karantanas, Kostas Marias and Thomas G. Maris

    Citation: European Radiology Experimental 2020 4:28

    Content type: Original article

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  20. Machine learning (ML) and deep learning (DL) systems, currently employed in medical image analysis, are data-driven models often considered as black boxes. However, improved transparency is needed to translate au...

    Authors: Giuseppe Baselli, Marina Codari and Francesco Sardanelli

    Citation: European Radiology Experimental 2020 4:30

    Content type: Hypothesis

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  21. Assessment of nigrostriatal degeneration is a key element to discriminate between dementia with Lewy bodies (DLB) and Alzheimer disease (AD), and it is often evaluated using ioflupane (123I-FP-CIT) single-photon ...

    Authors: Matteo Pardini, Flavio Nobili, Dario Arnaldi, Silvia Morbelli, Matteo Bauckneht, Roberto Rissotto, Carlo Serrati, Gianluca Serafini, Caterina Lapucci, Lucio Ghio, Mario Amore, Davide Massucco, Davide Sassos, Laura Bonzano, Giovanni Luigi Mancardi and Luca Roccatagliata

    Citation: European Radiology Experimental 2020 4:27

    Content type: Original article

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  22. Automatically detecting and quantifying pneumothorax on chest computed tomography (CT) may impact clinical decision-making. Machine learning methods published so far struggle with the heterogeneity of technica...

    Authors: Sebastian Röhrich, Thomas Schlegl, Constanze Bardach, Helmut Prosch and Georg Langs

    Citation: European Radiology Experimental 2020 4:26

    Content type: Original article

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  23. Timely diagnosis of cardiac iron overload is important for children with transfusion-dependent anaemias and requires modern measure methods. Nowadays, myocardial iron quantification is performed by magnetic re...

    Authors: E. E. Nazarova, G. V. Tereshchenko, D. A. Kupriyanov, N. S. Smetanina and G. A. Novichkova

    Citation: European Radiology Experimental 2020 4:25

    Content type: Original article

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  24. Uncorrected patient or prostate motion may impair targeting prostate areas during fusion image-guided procedures. We evaluated if a prototype “tracked Foley catheter” (TFC) could maintain fusion image alignmen...

    Authors: Graham R. Hale, Filippo Pesapane, Sheng Xu, Ivane Bakhutashvili, Neil Glossop, Baris Turkbey, Peter A. Pinto and Bradford J. Wood

    Citation: European Radiology Experimental 2020 4:24

    Content type: Original article

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  25. Dual-energy x-ray absorptiometry (DXA) can provide quantitative (bone mineral density, BMD) and qualitative (trabecular bone score, TBS) indexes of bone status, able to predict fragility fractures in most oste...

    Authors: Fabio Massimo Ulivieri, Luca Petruccio Piodi, Luca Rinaudo, Paolo Scanagatta and Bruno Mario Cesana

    Citation: European Radiology Experimental 2020 4:23

    Content type: Methodology

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  26. To evaluate whether machine learning algorithms allow the prediction of Child-Pugh classification on clinical multiphase computed tomography (CT).

    Authors: Johannes Thüring, Oliver Rippel, Christoph Haarburger, Dorit Merhof, Philipp Schad, Philipp Bruners, Christiane K. Kuhl and Daniel Truhn

    Citation: European Radiology Experimental 2020 4:20

    Content type: Original article

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  27. PRIMAGE is one of the largest and more ambitious research projects dealing with medical imaging, artificial intelligence and cancer treatment in children. It is a 4-year European Commission-financed project th...

    Authors: Luis Martí-Bonmatí, Ángel Alberich-Bayarri, Ruth Ladenstein, Ignacio Blanquer, J. Damian Segrelles, Leonor Cerdá-Alberich, Polyxeni Gkontra, Barbara Hero, J. M. García-Aznar, Daniel Keim, Wolfgang Jentner, Karine Seymour, Ana Jiménez-Pastor, Ismael González-Valverde, Blanca Martínez de las Heras, Samira Essiaf…

    Citation: European Radiology Experimental 2020 4:22

    Content type: Original article

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  28. Contrast-enhanced cardiac magnetic resonance (CMR) is pivotal for evaluating chronic myocardial infarction (CMI). Concerns about safety of gadolinium-based contrast agents favour dose reduction. We assessed im...

    Authors: Caterina Beatrice Monti, Marina Codari, Andrea Cozzi, Marco Alì, Lorenzo Saggiante, Francesco Sardanelli and Francesco Secchi

    Citation: European Radiology Experimental 2020 4:21

    Content type: Original article

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  29. Congenital vascular disease is one of the leading causes of death in paediatric age. Despite the importance of paediatric haemodynamics, large investigations have been devoted to the evaluation of circulation ...

    Authors: Parvin Mohammadyari, Giacomo Gadda, Angelo Taibi and Josep Munuera del Cerro

    Citation: European Radiology Experimental 2020 4:16

    Content type: Original article

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  30. Here, we summarise the unresolved debate about p value and its dichotomisation. We present the statement of the American Statistical Association against the misuse of statistical significance as well as the propo...

    Authors: Giovanni Di Leo and Francesco Sardanelli

    Citation: European Radiology Experimental 2020 4:18

    Content type: Methodology

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  31. The Monro-Kellie hypothesis (MKH) states that volume changes in any intracranial component (blood, brain tissue, cerebrospinal fluid) should be counterbalanced by a co-occurring opposite change to maintain int...

    Authors: Lisa A. van der Kleij, Jill B. De Vis, Jeroen de Bresser, Jeroen Hendrikse and Jeroen C. W. Siero

    Citation: European Radiology Experimental 2020 4:17

    Content type: Technical note

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  32. We aimed at reviewing design and realisation of perfusion/flow phantoms for validating quantitative perfusion imaging (PI) applications to encourage best practices.

    Authors: Marije E. Kamphuis, Marcel J. W. Greuter, Riemer H. J. A. Slart and Cornelis H. Slump

    Citation: European Radiology Experimental 2020 4:15

    Content type: Systematic review

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  33. Radiation dose in computed tomography (CT) has become a topic of high interest due to the increasing numbers of CT examinations performed worldwide. Hence, dose tracking and organ dose calculation software are...

    Authors: Cristina De Mattia, Federica Campanaro, Federica Rottoli, Paola Enrica Colombo, Andrea Pola, Angelo Vanzulli and Alberto Torresin

    Citation: European Radiology Experimental 2020 4:14

    Content type: Original article

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  35. Our aim was to compare women’s experience with automated breast ultrasound (ABUS) versus breast hand-held ultrasound (HHUS) and to evaluate their acceptance rate.

    Authors: Ilaria Mussetto, Licia Gristina, Simone Schiaffino, Simona Tosto, Edoardo Raviola and Massimo Calabrese

    Citation: European Radiology Experimental 2020 4:12

    Content type: Original article

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  36. Radiomics, artificial intelligence, and deep learning figure amongst recent buzzwords in current medical imaging research and technological development. Analysis of medical big data in assessment and follow-up...

    Authors: Roberto Gatta, Adrien Depeursinge, Osman Ratib, Olivier Michielin and Antoine Leimgruber

    Citation: European Radiology Experimental 2020 4:11

    Content type: Narrative review

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  38. Diffusion-weighted imaging (DWI) has shown great value in rectal cancer imaging. However, traditional DWI with echo-planar imaging (DW-EPI) often suffers from geometrical distortions. We applied a three-dimens...

    Authors: Qinwei Zhang, Petra J. van Houdt, Doenja M. J. Lambregts, Baukelien van Triest, Marnix P. M. Kop, Bram F. Coolen, Gustav J. Strijkers, Uulke A. van der Heide and Aart J. Nederveen

    Citation: European Radiology Experimental 2020 4:9

    Content type: Original article

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  39. To investigate the potential of semiquantitative time-intensity curve parameters compared to textural radiomic features on arterial phase images by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI...

    Authors: Roberta Fusco, Vincenza Granata, Francesca Maio, Mario Sansone and Antonella Petrillo

    Citation: European Radiology Experimental 2020 4:8

    Content type: Original article

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  40. Ultrasound (US) images are currently displayed on monitors, and their understanding needs good orientation skills. Direct overlay of US images onto the according anatomy is possible with augmented reality (AR)...

    Authors: Nadja A. Farshad-Amacker, Till Bay, Andrea B. Rosskopf, José M. Spirig, Florian Wanivenhaus, Christian W. A. Pfirrmann and Mazda Farshad

    Citation: European Radiology Experimental 2020 4:7

    Content type: Technical note

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  41. Bone age (BA) assessment performed by artificial intelligence (AI) is of growing interest due to improved accuracy, precision and time efficiency in daily routine. The aim of this study was to investigate the ...

    Authors: Christian Booz, Ibrahim Yel, Julian L. Wichmann, Sabine Boettger, Ahmed Al Kamali, Moritz H. Albrecht, Simon S. Martin, Lukas Lenga, Nicole A. Huizinga, Tommaso D’Angelo, Marco Cavallaro, Thomas J. Vogl and Boris Bodelle

    Citation: European Radiology Experimental 2020 4:6

    Content type: Original article

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  42. Differentiate malignant from benign enhancing foci on breast magnetic resonance imaging (MRI) through radiomic signature.

    Authors: Natascha C. D’Amico, Enzo Grossi, Giovanni Valbusa, Francesca Rigiroli, Bernardo Colombo, Massimo Buscema, Deborah Fazzini, Marco Ali, Ala Malasevschi, Gianpaolo Cornalba and Sergio Papa

    Citation: European Radiology Experimental 2020 4:5

    Content type: Original article

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  43. To reveal trends in bone microarchitectural parameters with increasing spatial resolution on ultra-high-resolution computed tomography (UHRCT) in vivo and to compare its performance with that of conventional-reso...

    Authors: Ryota Inai, Ryuichi Nakahara, Yusuke Morimitsu, Noriaki Akagi, Youhei Marukawa, Toshi Matsushita, Takashi Tanaka, Akihiro Tada, Takao Hiraki, Yoshihisa Nasu, Keiichiro Nishida, Toshifumi Ozaki and Susumu Kanazawa

    Citation: European Radiology Experimental 2020 4:4

    Content type: Original article

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  44. To examine in vitro acoustic property of nonalcoholic fatty disease in mouse and human liver to identify nonalcoholic steatohepatitis (NASH).

    Authors: Hitoshi Maruyama, Kazufumi Kobayashi, Soichiro Kiyono, Tetsuhiro Chiba, Naoya Kato, Masayuki Ohtsuka, Kazuyo Ito, Tadashi Yamaguchi and Shuichiro Shiina

    Citation: European Radiology Experimental 2020 4:3

    Content type: Original article

    Published on:

  45. A wide range of cancer immunotherapy approaches has been developed including non-specific immune-stimulants such as cytokines, cancer vaccines, immune checkpoint inhibitors (ICIs), and adoptive T cell therapy....

    Authors: Clarisse Dromain, Catherine Beigelman, Chiara Pozzessere, Rafael Duran and Antonia Digklia

    Citation: European Radiology Experimental 2020 4:2

    Content type: Systematic review

    Published on:

  46. Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a nove...

    Authors: Federica Ferrari, Giovanni Mauri, Luca Nicosia, Gianluca Maria Varano, Guido Bonomo and Franco Orsi

    Citation: European Radiology Experimental 2020 4:1

    Content type: Technical note

    Published on:

  47. After publication of this article [1], it is noticed it contained some errors in the Methods section.

    Authors: Stephanie Inhuber, Nico Sollmann, Sarah Schlaeger, Michael Dieckmeyer, Egon Burian, Caroline Kohlmeyer, Dimitrios C. Karampinos, Jan S. Kirschke, Thomas Baum, Florian Kreuzpointner and Ansgar Schwirtz

    Citation: European Radiology Experimental 2019 3:50

    Content type: Correction

    Published on:

    The original article was published in European Radiology Experimental 2019 3:45

  48. Hepatocellular carcinoma (HCC) guidelines recommend ultrasound screening in high-risk patients. However, in some patients, ultrasound image quality is suboptimal due to factors such as hepatic steatosis, cirrh...

    Authors: Michael Vinchill Chan, Stephen J. McDonald, Yang-Yi Ong, Katerina Mastrocostas, Edwin Ho, Ya Ruth Huo, Cositha Santhakumar, Alice Unah Lee and Jessica Yang

    Citation: European Radiology Experimental 2019 3:49

    Content type: Original article

    Published on:

  50. Flow diverters (FDs) are widely used in the treatment of intracranial aneurysms, but the required medication increases the risk of haemorrhagic complications and limits their use in the acute setting. Surface ...

    Authors: Tim Lenz-Habijan, Pervinder Bhogal, Catrin Bannewitz, Ralf Hannes, Hermann Monstadt, Andreas Simgen, Ruben Mühl-Benninghaus, Wolfgang Reith and Hans Henkes

    Citation: European Radiology Experimental 2019 3:47

    Content type: Original article

    Published on:

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