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  1. Machine learning (ML) and deep learning (DL) systems, currently employed in medical image analysis, are data-driven models often considered as black boxes. However, improved transparency is needed to translate au...

    Authors: Giuseppe Baselli, Marina Codari and Francesco Sardanelli

    Citation: European Radiology Experimental 2020 4:30

    Content type: Hypothesis

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  2. Assessment of nigrostriatal degeneration is a key element to discriminate between dementia with Lewy bodies (DLB) and Alzheimer disease (AD), and it is often evaluated using ioflupane (123I-FP-CIT) single-photon ...

    Authors: Matteo Pardini, Flavio Nobili, Dario Arnaldi, Silvia Morbelli, Matteo Bauckneht, Roberto Rissotto, Carlo Serrati, Gianluca Serafini, Caterina Lapucci, Lucio Ghio, Mario Amore, Davide Massucco, Davide Sassos, Laura Bonzano, Giovanni Luigi Mancardi and Luca Roccatagliata

    Citation: European Radiology Experimental 2020 4:27

    Content type: Original article

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  3. Automatically detecting and quantifying pneumothorax on chest computed tomography (CT) may impact clinical decision-making. Machine learning methods published so far struggle with the heterogeneity of technica...

    Authors: Sebastian Röhrich, Thomas Schlegl, Constanze Bardach, Helmut Prosch and Georg Langs

    Citation: European Radiology Experimental 2020 4:26

    Content type: Original article

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  4. Timely diagnosis of cardiac iron overload is important for children with transfusion-dependent anaemias and requires modern measure methods. Nowadays, myocardial iron quantification is performed by magnetic re...

    Authors: E. E. Nazarova, G. V. Tereshchenko, D. A. Kupriyanov, N. S. Smetanina and G. A. Novichkova

    Citation: European Radiology Experimental 2020 4:25

    Content type: Original article

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  5. Uncorrected patient or prostate motion may impair targeting prostate areas during fusion image-guided procedures. We evaluated if a prototype “tracked Foley catheter” (TFC) could maintain fusion image alignmen...

    Authors: Graham R. Hale, Filippo Pesapane, Sheng Xu, Ivane Bakhutashvili, Neil Glossop, Baris Turkbey, Peter A. Pinto and Bradford J. Wood

    Citation: European Radiology Experimental 2020 4:24

    Content type: Original article

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  6. Dual-energy x-ray absorptiometry (DXA) can provide quantitative (bone mineral density, BMD) and qualitative (trabecular bone score, TBS) indexes of bone status, able to predict fragility fractures in most oste...

    Authors: Fabio Massimo Ulivieri, Luca Petruccio Piodi, Luca Rinaudo, Paolo Scanagatta and Bruno Mario Cesana

    Citation: European Radiology Experimental 2020 4:23

    Content type: Methodology

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  7. To evaluate whether machine learning algorithms allow the prediction of Child-Pugh classification on clinical multiphase computed tomography (CT).

    Authors: Johannes Thüring, Oliver Rippel, Christoph Haarburger, Dorit Merhof, Philipp Schad, Philipp Bruners, Christiane K. Kuhl and Daniel Truhn

    Citation: European Radiology Experimental 2020 4:20

    Content type: Original article

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  8. PRIMAGE is one of the largest and more ambitious research projects dealing with medical imaging, artificial intelligence and cancer treatment in children. It is a 4-year European Commission-financed project th...

    Authors: Luis Martí-Bonmatí, Ángel Alberich-Bayarri, Ruth Ladenstein, Ignacio Blanquer, J. Damian Segrelles, Leonor Cerdá-Alberich, Polyxeni Gkontra, Barbara Hero, J. M. García-Aznar, Daniel Keim, Wolfgang Jentner, Karine Seymour, Ana Jiménez-Pastor, Ismael González-Valverde, Blanca Martínez de las Heras, Samira Essiaf…

    Citation: European Radiology Experimental 2020 4:22

    Content type: Original article

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  9. Contrast-enhanced cardiac magnetic resonance (CMR) is pivotal for evaluating chronic myocardial infarction (CMI). Concerns about safety of gadolinium-based contrast agents favour dose reduction. We assessed im...

    Authors: Caterina Beatrice Monti, Marina Codari, Andrea Cozzi, Marco Alì, Lorenzo Saggiante, Francesco Sardanelli and Francesco Secchi

    Citation: European Radiology Experimental 2020 4:21

    Content type: Original article

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  10. Congenital vascular disease is one of the leading causes of death in paediatric age. Despite the importance of paediatric haemodynamics, large investigations have been devoted to the evaluation of circulation ...

    Authors: Parvin Mohammadyari, Giacomo Gadda, Angelo Taibi and Josep Munuera del Cerro

    Citation: European Radiology Experimental 2020 4:16

    Content type: Original article

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  11. Here, we summarise the unresolved debate about p value and its dichotomisation. We present the statement of the American Statistical Association against the misuse of statistical significance as well as the propo...

    Authors: Giovanni Di Leo and Francesco Sardanelli

    Citation: European Radiology Experimental 2020 4:18

    Content type: Methodology

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  12. The Monro-Kellie hypothesis (MKH) states that volume changes in any intracranial component (blood, brain tissue, cerebrospinal fluid) should be counterbalanced by a co-occurring opposite change to maintain int...

    Authors: Lisa A. van der Kleij, Jill B. De Vis, Jeroen de Bresser, Jeroen Hendrikse and Jeroen C. W. Siero

    Citation: European Radiology Experimental 2020 4:17

    Content type: Technical note

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  13. We aimed at reviewing design and realisation of perfusion/flow phantoms for validating quantitative perfusion imaging (PI) applications to encourage best practices.

    Authors: Marije E. Kamphuis, Marcel J. W. Greuter, Riemer H. J. A. Slart and Cornelis H. Slump

    Citation: European Radiology Experimental 2020 4:15

    Content type: Systematic review

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  14. Radiation dose in computed tomography (CT) has become a topic of high interest due to the increasing numbers of CT examinations performed worldwide. Hence, dose tracking and organ dose calculation software are...

    Authors: Cristina De Mattia, Federica Campanaro, Federica Rottoli, Paola Enrica Colombo, Andrea Pola, Angelo Vanzulli and Alberto Torresin

    Citation: European Radiology Experimental 2020 4:14

    Content type: Original article

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  16. Our aim was to compare women’s experience with automated breast ultrasound (ABUS) versus breast hand-held ultrasound (HHUS) and to evaluate their acceptance rate.

    Authors: Ilaria Mussetto, Licia Gristina, Simone Schiaffino, Simona Tosto, Edoardo Raviola and Massimo Calabrese

    Citation: European Radiology Experimental 2020 4:12

    Content type: Original article

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  17. Radiomics, artificial intelligence, and deep learning figure amongst recent buzzwords in current medical imaging research and technological development. Analysis of medical big data in assessment and follow-up...

    Authors: Roberto Gatta, Adrien Depeursinge, Osman Ratib, Olivier Michielin and Antoine Leimgruber

    Citation: European Radiology Experimental 2020 4:11

    Content type: Narrative review

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  19. Diffusion-weighted imaging (DWI) has shown great value in rectal cancer imaging. However, traditional DWI with echo-planar imaging (DW-EPI) often suffers from geometrical distortions. We applied a three-dimens...

    Authors: Qinwei Zhang, Petra J. van Houdt, Doenja M. J. Lambregts, Baukelien van Triest, Marnix P. M. Kop, Bram F. Coolen, Gustav J. Strijkers, Uulke A. van der Heide and Aart J. Nederveen

    Citation: European Radiology Experimental 2020 4:9

    Content type: Original article

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  20. To investigate the potential of semiquantitative time-intensity curve parameters compared to textural radiomic features on arterial phase images by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI...

    Authors: Roberta Fusco, Vincenza Granata, Francesca Maio, Mario Sansone and Antonella Petrillo

    Citation: European Radiology Experimental 2020 4:8

    Content type: Original article

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  21. Ultrasound (US) images are currently displayed on monitors, and their understanding needs good orientation skills. Direct overlay of US images onto the according anatomy is possible with augmented reality (AR)...

    Authors: Nadja A. Farshad-Amacker, Till Bay, Andrea B. Rosskopf, José M. Spirig, Florian Wanivenhaus, Christian W. A. Pfirrmann and Mazda Farshad

    Citation: European Radiology Experimental 2020 4:7

    Content type: Technical note

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  22. Bone age (BA) assessment performed by artificial intelligence (AI) is of growing interest due to improved accuracy, precision and time efficiency in daily routine. The aim of this study was to investigate the ...

    Authors: Christian Booz, Ibrahim Yel, Julian L. Wichmann, Sabine Boettger, Ahmed Al Kamali, Moritz H. Albrecht, Simon S. Martin, Lukas Lenga, Nicole A. Huizinga, Tommaso D’Angelo, Marco Cavallaro, Thomas J. Vogl and Boris Bodelle

    Citation: European Radiology Experimental 2020 4:6

    Content type: Original article

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  23. Differentiate malignant from benign enhancing foci on breast magnetic resonance imaging (MRI) through radiomic signature.

    Authors: Natascha C. D’Amico, Enzo Grossi, Giovanni Valbusa, Francesca Rigiroli, Bernardo Colombo, Massimo Buscema, Deborah Fazzini, Marco Ali, Ala Malasevschi, Gianpaolo Cornalba and Sergio Papa

    Citation: European Radiology Experimental 2020 4:5

    Content type: Original article

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  24. To reveal trends in bone microarchitectural parameters with increasing spatial resolution on ultra-high-resolution computed tomography (UHRCT) in vivo and to compare its performance with that of conventional-reso...

    Authors: Ryota Inai, Ryuichi Nakahara, Yusuke Morimitsu, Noriaki Akagi, Youhei Marukawa, Toshi Matsushita, Takashi Tanaka, Akihiro Tada, Takao Hiraki, Yoshihisa Nasu, Keiichiro Nishida, Toshifumi Ozaki and Susumu Kanazawa

    Citation: European Radiology Experimental 2020 4:4

    Content type: Original article

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  25. To examine in vitro acoustic property of nonalcoholic fatty disease in mouse and human liver to identify nonalcoholic steatohepatitis (NASH).

    Authors: Hitoshi Maruyama, Kazufumi Kobayashi, Soichiro Kiyono, Tetsuhiro Chiba, Naoya Kato, Masayuki Ohtsuka, Kazuyo Ito, Tadashi Yamaguchi and Shuichiro Shiina

    Citation: European Radiology Experimental 2020 4:3

    Content type: Original article

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  26. A wide range of cancer immunotherapy approaches has been developed including non-specific immune-stimulants such as cytokines, cancer vaccines, immune checkpoint inhibitors (ICIs), and adoptive T cell therapy....

    Authors: Clarisse Dromain, Catherine Beigelman, Chiara Pozzessere, Rafael Duran and Antonia Digklia

    Citation: European Radiology Experimental 2020 4:2

    Content type: Systematic review

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  27. Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a nove...

    Authors: Federica Ferrari, Giovanni Mauri, Luca Nicosia, Gianluca Maria Varano, Guido Bonomo and Franco Orsi

    Citation: European Radiology Experimental 2020 4:1

    Content type: Technical note

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  28. After publication of this article [1], it is noticed it contained some errors in the Methods section.

    Authors: Stephanie Inhuber, Nico Sollmann, Sarah Schlaeger, Michael Dieckmeyer, Egon Burian, Caroline Kohlmeyer, Dimitrios C. Karampinos, Jan S. Kirschke, Thomas Baum, Florian Kreuzpointner and Ansgar Schwirtz

    Citation: European Radiology Experimental 2019 3:50

    Content type: Correction

    Published on:

    The original article was published in European Radiology Experimental 2019 3:45

  29. Hepatocellular carcinoma (HCC) guidelines recommend ultrasound screening in high-risk patients. However, in some patients, ultrasound image quality is suboptimal due to factors such as hepatic steatosis, cirrh...

    Authors: Michael Vinchill Chan, Stephen J. McDonald, Yang-Yi Ong, Katerina Mastrocostas, Edwin Ho, Ya Ruth Huo, Cositha Santhakumar, Alice Unah Lee and Jessica Yang

    Citation: European Radiology Experimental 2019 3:49

    Content type: Original article

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  31. Flow diverters (FDs) are widely used in the treatment of intracranial aneurysms, but the required medication increases the risk of haemorrhagic complications and limits their use in the acute setting. Surface ...

    Authors: Tim Lenz-Habijan, Pervinder Bhogal, Catrin Bannewitz, Ralf Hannes, Hermann Monstadt, Andreas Simgen, Ruben Mühl-Benninghaus, Wolfgang Reith and Hans Henkes

    Citation: European Radiology Experimental 2019 3:47

    Content type: Original article

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  32. We investigated the influence of dose, spectral separation, pitch, rotation time, and reconstruction kernel on accuracy and image noise of virtual non-calcium images using a bone marrow phantom.

    Authors: Felix C. Müller, Henrik Børgesen, Kasper Gosvig, Anders Rodell, Christian Booz, Bernhard Schmidt, Bernhard Krauss and Mikael Boesen

    Citation: European Radiology Experimental 2019 3:46

    Content type: Original article

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  33. Assessment of the thigh muscle fat composition using magnetic resonance imaging (MRI) can provide surrogate markers in subjects suffering from various musculoskeletal disorders including knee osteoarthritis or...

    Authors: Stephanie Inhuber, Nico Sollmann, Sarah Schlaeger, Michael Dieckmeyer, Egon Burian, Caroline Kohlmeyer, Dimitrios C. Karampinos, Jan S. Kirschke, Thomas Baum, Florian Kreuzpointner and Ansgar Schwirtz

    Citation: European Radiology Experimental 2019 3:45

    Content type: Original article

    Published on:

    The Correction to this article has been published in European Radiology Experimental 2019 3:50

  34. Our aims were to determine if features derived from texture analysis (TA) can distinguish normal, benign, and malignant tissue on automated breast ultrasound (ABUS); to evaluate whether machine learning (ML) a...

    Authors: Magda Marcon, Alexander Ciritsis, Cristina Rossi, Anton S. Becker, Nicole Berger, Moritz C. Wurnig, Matthias W. Wagner, Thomas Frauenfelder and Andreas Boss

    Citation: European Radiology Experimental 2019 3:44

    Content type: Original article

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  35. Segmentation of computed tomography (CT) images provides quantitative data on body tissue composition, which may greatly impact the development and progression of diseases such as type 2 diabetes mellitus and ...

    Authors: Lisa Jannicke Kjønigsen, Magnus Harneshaug, Ann-Monica Fløtten, Lena Korsmo Karterud, Kent Petterson, Grethe Skjolde, Heidi B. Eggesbø, Harald Weedon-Fekjær, Hege Berg Henriksen and Peter M. Lauritzen

    Citation: European Radiology Experimental 2019 3:42

    Content type: Original article

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  36. Liver alignment between series/exams is challenged by dynamic morphology or variability in patient positioning or motion. Image registration can improve image interpretation and lesion co-localization. We asse...

    Authors: Kyle A. Hasenstab, Guilherme Moura Cunha, Atsushi Higaki, Shintaro Ichikawa, Kang Wang, Timo Delgado, Ryan L. Brunsing, Alexandra Schlein, Leornado Kayat Bittencourt, Armin Schwartzman, Katie J. Fowler, Albert Hsiao and Claude B. Sirlin

    Citation: European Radiology Experimental 2019 3:43

    Content type: Original article

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  37. Cardiac magnetic resonance imaging (MRI) in large animals is cumbersome for various reasons, including ethical considerations, costs of housing and maintenance, and need for anaesthesia. Our primary purpose wa...

    Authors: Eva S. Peper, Alberto M. Leopaldi, Sjoerd van Tuijl, Bram F. Coolen, Gustav J. Strijkers, Jan Baan Jr, R. Nils Planken, Arend de Weger, Aart J. Nederveen, Henk A. Marquering and Pim van Ooij

    Citation: European Radiology Experimental 2019 3:40

    Content type: Original article

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  38. To develop a supervised machine learning (ML) algorithm predicting above- versus below-median overall survival (OS) from diffusion-weighted imaging-derived radiomic features in patients with pancreatic ductal ade...

    Authors: Georgios Kaissis, Sebastian Ziegelmayer, Fabian Lohöfer, Hana Algül, Matthias Eiber, Wilko Weichert, Roland Schmid, Helmut Friess, Ernst Rummeny, Donna Ankerst, Jens Siveke and Rickmer Braren

    Citation: European Radiology Experimental 2019 3:41

    Content type: Original article

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  40. Real-time dosimeters may create a relatively safer environment not only for the patient but also for the physician and the assistant as well. We propose the use of a real-time radiation measurement dosimeter h...

    Authors: Muhammad Umair Ahmad Khan and Byung-Ju Yi

    Citation: European Radiology Experimental 2019 3:38

    Content type: Original article

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  41. Structured reports have been shown to improve communication between radiologists and providers. However, some radiologists are concerned about resultant decreased workflow efficiency. We tested a machine learn...

    Authors: Adam Spandorfer, Cody Branch, Puneet Sharma, Pooyan Sahbaee, U. Joseph Schoepf, James G. Ravenel and John W. Nance

    Citation: European Radiology Experimental 2019 3:37

    Content type: Original article

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  42. Computed tomography can provide high-resolution details on nasal anatomy being potentially useful for the assessment of nasal spray deposition. The purpose of this technical note was to present a method based ...

    Authors: Thomas Sartoretti, Manoj Mannil, Stefan Biendl, Johannes M. Froehlich, Hatem Alkadhi and Matthias Zadory

    Citation: European Radiology Experimental 2019 3:32

    Content type: Technical note

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  43. To investigate whether quantitative radiomic features extracted from digital breast tomosynthesis (DBT) are associated with Ki-67 expression of breast cancer.

    Authors: Alberto Stefano Tagliafico, Bianca Bignotti, Federica Rossi, Joao Matos, Massimo Calabrese, Francesca Valdora and Nehmat Houssami

    Citation: European Radiology Experimental 2019 3:36

    Content type: Original article

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  44. Bone strain index (BSI) is a tool measuring bone strain, derived from dual x-ray photon absorptiometry. It is able to characterise an aspect of bone quality that, joined to the quantity and quality parameters of ...

    Authors: C. Messina, L. P. Piodi, L. Rinaudo, I. Emili, F. Porro, C. Buonomenna, L. M. Sconfienza, L. Vergani and F. M. Ulivieri

    Citation: European Radiology Experimental 2019 3:33

    Content type: Original article

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  45. Application of an endorectal coil (ERC) for 3.0-T prostate magnetic resonance imaging (MRI) is contentious. We hypothesised that a multicoil phased-array protocol provides T2-weighted images (T2WI) and diffusi...

    Authors: Sophie Murer, Juergen Scheidler, Ulrike L. Mueller-Lisse, Marissa Helling, Michael Scherr and Ullrich G. Mueller-Lisse

    Citation: European Radiology Experimental 2019 3:30

    Content type: Original article

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  46. With this review, we aimed to provide a synopsis of recently proposed applications of machine learning (ML) in radiology focusing on prostate magnetic resonance imaging (MRI). After defining the difference bet...

    Authors: Renato Cuocolo, Maria Brunella Cipullo, Arnaldo Stanzione, Lorenzo Ugga, Valeria Romeo, Leonardo Radice, Arturo Brunetti and Massimo Imbriaco

    Citation: European Radiology Experimental 2019 3:35

    Content type: Narrative review

    Published on:

  47. Preoperative evaluation of nipple-areola complex (NAC) tumour involvement is crucial to select patients candidates for nipple-sparing mastectomy. Our aim was to validate a previously developed automated method...

    Authors: Marta D’Alonzo, Laura Martincich, Agnese Fenoglio, Valentina Giannini, Lisa Cellini, Viola Liberale and Nicoletta Biglia

    Citation: European Radiology Experimental 2019 3:31

    Content type: Original article

    Published on:

  49. Whole-heart magnetic resonance angiography (MRA) requires sophisticated methods accounting for respiratory motion. Our purpose was to evaluate the image quality of compressed sensing-based respiratory motion-r...

    Authors: Robert E. Stroud, Davide Piccini, U. Joseph Schoepf, John Heerfordt, Jérôme Yerly, Lorenzo Di Sopra, Jonathan D. Rollins, Andreas M. Fischer, Pal Suranyi and Akos Varga-Szemes

    Citation: European Radiology Experimental 2019 3:29

    Content type: Original article

    Published on:

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