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  1. Airways segmentation is important for research about pulmonary disease but require a large amount of time by trained specialists. We used an openly available software to improve airways segmentations obtained ...

    Authors: Ivan Dudurych, Antonio Garcia-Uceda, Zaigham Saghir, Harm A. W. M. Tiddens, Rozemarijn Vliegenthart and Marleen de Bruijne
    Citation: European Radiology Experimental 2021 5:54
    Content type: Technical note Published on:

  2. Radical cystectomy for urinary bladder cancer is a procedure associated with a high risk of complications, and poor overall survival (OS) due to both patient and tumour factors. Sarcopenia is one such patient ...

    Authors: Thomas Ying, Pablo Borrelli, Lars Edenbrandt, Olof Enqvist, Reza Kaboteh, Elin Trägårdh, Johannes Ulén and Henrik Kjölhede
    Citation: European Radiology Experimental 2021 5:50
    Content type: Original article Published on:

  4. The technical requirements for the acquisition of multiparametric magnetic resonance imaging (mpMRI) of the prostate have been clearly outlined in the Prostate Imaging Reporting and Data System (PI-RADS) guide...

    Authors: Francesco Giganti, Sydney Lindner, Jonathan W. Piper, Veeru Kasivisvanathan, Mark Emberton, Caroline M. Moore and Clare Allen
    Citation: European Radiology Experimental 2021 5:48
    Content type: Technical note Published on:

  5. We applied an artificial intelligence-based model to predict fragility fractures in postmenopausal women, using different dual-energy x-ray absorptiometry (DXA) parameters.

    Authors: Fabio Massimo Ulivieri, Luca Rinaudo, Carmelo Messina, Luca Petruccio Piodi, Davide Capra, Barbara Lupi, Camilla Meneguzzo, Luca Maria Sconfienza, Francesco Sardanelli, Andrea Giustina and Enzo Grossi
    Citation: European Radiology Experimental 2021 5:47
    Content type: Original article Published on:

  6. Previous intraindividual comparative studies evaluating gadobutrol and gadoteridol for contrast-enhanced magnetic resonance imaging (MRI) of brain tumours have relied on subjective image assessment, potentiall...

    Authors: Matthew J. Kuhn, Julia W. Patriarche, Douglas Patriarche, Miles A. Kirchin, Massimo Bona and Gianpaolo Pirovano
    Citation: European Radiology Experimental 2021 5:46
    Content type: Original article Published on:

  7. Aquaporin-4 is a membrane channel protein that is highly expressed in brain astrocytes and facilitates the transport of water molecules. It has been suggested that suppression of aquaporin-4 function may be an...

    Authors: Takuya Urushihata, Hiroyuki Takuwa, Manami Takahashi, Jeff Kershaw, Yasuhiko Tachibana, Nobuhiro Nitta, Sayaka Shibata, Masato Yasui, Makoto Higuchi and Takayuki Obata
    Citation: European Radiology Experimental 2021 5:44
    Content type: Original article Published on:

  8. Dual-source dual-energy computed tomography (DECT) offers the potential for opportunistic osteoporosis screening by enabling phantomless bone mineral density (BMD) quantification. This study sought to assess t...

    Authors: Vitali Koch, Nils Große Hokamp, Moritz H. Albrecht, Leon D. Gruenewald, Ibrahim Yel, Jan Borggrefe, Stefan Wesarg, Katrin Eichler, Iris Burck, Tatjana Gruber-Rouh, Lukas Lenga, Thomas J. Vogl, Simon S. Martin, Julian L. Wichmann, Renate M. Hammerstingl, Leona S. Alizadeh…
    Citation: European Radiology Experimental 2021 5:43
    Content type: Original article Published on:

  9. Chronic pulmonary embolism (CPE) is a life-threatening disease easily misdiagnosed on computed tomography. We investigated a three-dimensional convolutional neural network (CNN) algorithm for detecting hypoper...

    Authors: Tuomas Vainio, Teemu Mäkelä, Sauli Savolainen and Marko Kangasniemi
    Citation: European Radiology Experimental 2021 5:45
    Content type: Original article Published on:

  10. In hepatobiliary imaging, systems detect the total amount of agents originating from extracellular space, bile canaliculi, and hepatocytes. They add in situ concentration of each compartment corrected by its resp...

    Authors: Catherine M. Pastor, Florian Joly, Valérie Vilgrain and Philippe Millet
    Citation: European Radiology Experimental 2021 5:42
    Content type: Original article Published on:

  11. Transperineal laser ablation (TPLA) of the prostate is a novel, mini-invasive option for men with lower urinary tract symptoms (LUTS) due to benign prostate hyperplasia (BPH). Our aim was to assess the impact ...

    Authors: Guglielmo Manenti, Tommaso Perretta, Antonello Calcagni, Donatella Ferrari, Colleen P. Ryan, Federico Fraioli, Rosaria Meucci, Andrea Malizia, Valerio Iacovelli, Enrico Finazzi Agrò and Roberto Floris
    Citation: European Radiology Experimental 2021 5:41
    Content type: Original article Published on:

  12. Our aim was to demonstrate that automated detection and classification of breast microcalcifications, according to Breast Imaging Reporting and Data System (BI-RADS) categorisation, can be improved with the su...

    Authors: Kosmia Loizidou, Galateia Skouroumouni, Costas Pitris and Christos Nikolaou
    Citation: European Radiology Experimental 2021 5:40
    Content type: Original article Published on:

  13. Assessment of image noise is a relevant issue in computed tomography (CT). Noise is routinely measured by the standard deviation of density values (Hounsfield units, HU) within a circular region of interest (R...

    Authors: Hendrik Joost Wisselink, Gert Jan Pelgrim, Mieneke Rook, Ivan Dudurych, Maarten van den Berge, Geertruida H. de Bock and Rozemarijn Vliegenthart
    Citation: European Radiology Experimental 2021 5:39
    Content type: Technical note Published on:

  14. Dual-energy CT (DECT) has emerged into clinical routine as an imaging technique with unique postprocessing utilities that improve the evaluation of different body areas. The virtual non-calcium (VNCa) reconstr...

    Authors: Tommaso D’Angelo, Moritz H. Albrecht, Danilo Caudo, Silvio Mazziotti, Thomas J. Vogl, Julian L. Wichmann, Simon Martin, Ibrahim Yel, Giorgio Ascenti, Vitali Koch, Giuseppe Cicero, Alfredo Blandino and Christian Booz
    Citation: European Radiology Experimental 2021 5:38
    Content type: Narrative review Published on:

  15. In the last 20 years, ultra-high field (UHF) magnetic resonance imaging (MRI) has become an outstanding research tool for the study of the human brain, with 90 of these scanners installed today, worldwide. The...

    Authors: Mirco Cosottini and Luca Roccatagliata
    Citation: European Radiology Experimental 2021 5:37
    Content type: Editorial Published on:

  16. Ultra-high-field (UHF) magnetic resonance (MR) scanners, that is, equipment operating at static magnetic field of 7 tesla (7 T) and above, enable the acquisition of data with greatly improved signal-to-noise r...

    Authors: Emrah Düzel, Mauro Costagli, Graziella Donatelli, Oliver Speck and Mirco Cosottini
    Citation: European Radiology Experimental 2021 5:36
    Content type: Narrative review Published on:

  17. Research in ultrahigh magnetic field strength combined with ultrahigh and ultrafast gradient technology has provided enormous gains in sensitivity, resolution, and contrast for neuroimaging. This article provi...

    Authors: Behroze Vachha and Susie Y. Huang
    Citation: European Radiology Experimental 2021 5:35
    Content type: Narrative review Published on:

  18. We investigated mitral valve annular geometry changes during the cardiac cycle in patients with severe mitral regurgitation (MR) who underwent cardiac computed tomography angiography (CCTA) prior to percutaneo...

    Authors: Anna Palmisano, Valeria Nicoletti, Caterina Colantoni, Caterina Beatrice Monti, Luigi Pannone, Davide Vignale, Fatemeh Darvizeh, Eustachio Agricola, Simone Schaffino, Francesco De Cobelli and Antonio Esposito
    Citation: European Radiology Experimental 2021 5:34
    Content type: Original article Published on:

  19. To evaluate the feasibility of two-colour index maps containing combined diffusion and perfusion information from simplified intravoxel incoherent motion (IVIM) for liver lesion malignancy assessment.

    Authors: Petra Mürtz, Narine Mesropyan, Alois M. Sprinkart, Wolfgang Block, Julian A. Luetkens, Ulrike Attenberger and Claus C. Pieper
    Citation: European Radiology Experimental 2021 5:33
    Content type: Original article Published on:

  20. Angiogenesis is prominent in metastatic renal cell carcinoma (mRCC). We compared two angiogenesis assessment methods: dynamic contrast-enhanced computed tomography (DCE-CT)-derived blood volume (BV) and blood ...

    Authors: Aska Drljevic-Nielsen, Finn Rasmussen, Patricia Switten Nielsen, Christina Stilling, Kennet Thorup, Jill Rachel Mains, Hans Henrik Torp Madsen and Frede Donskov
    Citation: European Radiology Experimental 2021 5:32
    Content type: Original article Published on:

  21. Two-dimensional (2D) ultrasound is well established for thyroid nodule assessment and treatment guidance. However, it is hampered by a limited field of view and observer variability that may lead to inaccurate...

    Authors: T. Boers, S. J. Braak, M. Versluis and S. Manohar
    Citation: European Radiology Experimental 2021 5:31
    Content type: Original article Published on:

  22. With advancements in computer systems, computer graphics and medical imaging technologies, clinicians strive for a personalised approach to patient treatment. Therefore, the production of personalised surgical...

    Authors: Luka Šimić, Vjekoslav Kopačin, Ivan Mumlek, Josip Butković and Vedran Zubčić
    Citation: European Radiology Experimental 2021 5:30
    Content type: Technical note Published on:

  23. Telesonography systems have been developed to overcome barriers to accessing diagnostic ultrasound for patients in rural and remote communities. However, most previous telesonography systems have been designed...

    Authors: Mohammed Obaid, Qianwei Zhang, Scott J. Adams, Reza Fotouhi and Haron Obaid
    Citation: European Radiology Experimental 2021 5:29
    Content type: Original article Published on:

  24. To evaluate the performance of a decision support system (DSS) based on radiomics and machine learning in predicting the risk of malignancy of ovarian masses (OMs) from transvaginal ultrasonography (TUS) and s...

    Authors: Valentina Chiappa, Matteo Interlenghi, Giorgio Bogani, Christian Salvatore, Francesca Bertolina, Giuseppe Sarpietro, Mauro Signorelli, Dominique Ronzulli, Isabella Castiglioni and Francesco Raspagliesi
    Citation: European Radiology Experimental 2021 5:28
    Content type: Original article Published on:

  26. Cerebrospinal fluid shunts in the treatment of hydrocephalus, although associated with clinical benefit, have a high failure rate with repeat computed tomography (CT) imaging resulting in a substantial cumulat...

    Authors: David J. Ryan, Richard G. Kavanagh, Stella Joyce, Mika O’Callaghan Maher, Niamh Moore, Aisling McMahon, Deirdre Hussey, Michael G. J. O’Sullivan, Gerald Wyse, Noel Fanning, Owen J. O’Connor and Michael M. Maher
    Citation: European Radiology Experimental 2021 5:26
    Content type: Original article Published on:

  27. Computed tomography angiography (CTA) imaging is needed in current guideline-based stroke diagnosis, and infarct core size is one factor in guiding treatment decisions. We studied the efficacy of a convolution...

    Authors: Lasse Hokkinen, Teemu Mäkelä, Sauli Savolainen and Marko Kangasniemi
    Citation: European Radiology Experimental 2021 5:25
    Content type: Original article Published on:

  28. The aim of this study was to quantitatively benchmark iodine imaging across specific virtual monoenergetic energy levels, iodine maps and virtual non-contrast images with different phantom sizes and iodine con...

    Authors: Vanja Harsaker, Kristin Jensen, Hilde Kjernlie Andersen and Anne Catrine Martinsen
    Citation: European Radiology Experimental 2021 5:24
    Content type: Original article Published on:

  29. Magnetic resonance imaging (MRI) has become an essential diagnostic modality for congenital disorders of the central nervous system. Recent advancements have transformed foetal MRI into a clinically feasible t...

    Authors: Andras Jakab, Kelly Payette, Luca Mazzone, Sonja Schauer, Cécile Olivia Muller, Raimund Kottke, Nicole Ochsenbein-Kölble, Ruth Tuura, Ueli Moehrlen and Martin Meuli
    Citation: European Radiology Experimental 2021 5:23
    Content type: Narrative review Published on:

  30. There is limited scientific evidence on the potential of spectral computed tomography (SCT) for differentiation of nodules in the cirrhotic liver. We aimed to assess SCT-generated material density (MD) paramet...

    Authors: Shalini Thapar Laroia, Komal Yadav, Senthil Kumar, Archana Rastogi, Guresh Kumar and Shiv Kumar Sarin
    Citation: European Radiology Experimental 2021 5:22
    Content type: Original article Published on:

  31. On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) pandemic. The expert organisations recommend more cautious use of thoracic computed tomography (CT), opting for...

    Authors: Victor Gombolevskiy, Sergey Morozov, Valeria Chernina, Ivan Blokhin and Jenia Vassileva
    Citation: European Radiology Experimental 2021 5:21
    Content type: Technical note Published on:

  32. PRIMAGE is a European Commission-financed project dealing with medical imaging and artificial intelligence aiming to create an imaging biobank in oncology. The project includes a task dedicated to the interope...

    Authors: Camilla Scapicchio, Michela Gabelloni, Sara Maria Forte, Leonor Cerdá Alberich, Lorenzo Faggioni, Rita Borgheresi, Paola Erba, Fabiola Paiar, Luis Marti-Bonmati and Emanuele Neri
    Citation: European Radiology Experimental 2021 5:20
    Content type: Methodology Published on:

  33. Magnetic resonance imaging (MRI) is the modality of choice for evaluating soft tissue damage along the spine in the emergency setting, yet access and fast protocol availability are limited. We assessed the per...

    Authors: Nico Sollmann, Charlotte Rüther, Simon Schön, Claus Zimmer, Thomas Baum and Jan S. Kirschke
    Citation: European Radiology Experimental 2021 5:19
    Content type: Original article Published on:

  34. In this study, we investigated the influence of beam hardening on the dual-energy computed tomography (DECT) values of iodine maps, virtual monoenergetic (VME) images, and virtual non-contrast (VNC) images. 32...

    Authors: Risa Kanatani, Takashi Shirasaka, Tsukasa Kojima, Toyoyuki Kato and Masateru Kawakubo
    Citation: European Radiology Experimental 2021 5:18
    Content type: Technical note Published on:

  35. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Cristian Giuseppe Monaco, Federico Zaottini, Simone Schiaffino, Alessandro Villa, Gianmarco Della Pepa, Luca Alessandro Carbonaro, Laura Menicagli, Andrea Cozzi, Serena Carriero, Francesco Arpaia, Giovanni Di Leo, Davide Astengo, Ilan Rosenberg and Francesco Sardanelli
    Citation: European Radiology Experimental 2021 5:17
    Content type: Correction Published on:

    The original article was published in European Radiology Experimental 2020 4:68

  36. Our aim was to compare the diagnostic performance of quantitative dual-layer spectral computed tomography (DLSCT) and axillary ultrasound (US) for diagnosing lymph node metastases in breast cancer patients.

    Authors: Thomas Winther Buus, Mads Sandahl, Kennet Sønderstgaard Thorup, Finn Rasmussen, Søren Redsted, Peer Christiansen, Anders Bonde Jensen and Erik Morre Pedersen
    Citation: European Radiology Experimental 2021 5:16
    Content type: Original article Published on:

  37. Although dorsal/palmar tilt, radial inclination (RI), and ulnar variance (UV) are measurements commonly performed in wrist radiographs, the impact of forearm rotation on those measurements during the radiograp...

    Authors: Janni Jensen, Hans B. Tromborg, Benjamin S. B. Rasmussen, Oke Gerke, Trine Torfing, Helle Precht and Ole Graumann
    Citation: European Radiology Experimental 2021 5:15
    Content type: Original article Published on:

  38. Ischemic heart disease and its sequelae are one of the major contributors to morbidity and mortality worldwide. Over the last decades, technological developments have strengthened the role of noninvasive imagi...

    Authors: Tilman Emrich, Moritz Halfmann, U. Joseph Schoepf and Karl-Friedrich Kreitner
    Citation: European Radiology Experimental 2021 5:14
    Content type: Narrative review Published on:

  40. After an ischemic event, disruptive changes in the healthy myocardium may gradually develop and may ultimately turn into fibrotic scar. While these structural changes have been described by conventional imagin...

    Authors: Martin J. Willemink, Akos Varga-Szemes, U. Joseph Schoepf, Marina Codari, Koen Nieman, Dominik Fleischmann and Domenico Mastrodicasa
    Citation: European Radiology Experimental 2021 5:12
    Content type: Narrative review Published on:

  41. Body composition is associated with survival outcome in oncological patients, but it is not routinely calculated. Manual segmentation of subcutaneous adipose tissue (SAT) and muscle is time-consuming and there...

    Authors: Pablo Borrelli, Reza Kaboteh, Olof Enqvist, Johannes Ulén, Elin Trägårdh, Henrik Kjölhede and Lars Edenbrandt
    Citation: European Radiology Experimental 2021 5:11
    Content type: Original article Published on:

  42. No chemotherapeutic agents have been standardised for transarterial chemoembolisation (TACE). In particular, doxorubicin has no defined optimal dosage in TACE procedures. We compared low versus currently used dos...

    Authors: Ahmed A. Bessar, Ahmed Farag, Sameh M. Abdel Monem, Fady M. Wadea, Shady E. Shaker, Mahmoud Ahmed Ebada and Manar A. Bessar
    Citation: European Radiology Experimental 2021 5:10
    Content type: Original article Published on:

  43. Rib fractures are associated with considerable morbidity and mortality. Surgical stabilization of rib fractures (SSRF) can be performed to mitigate complications. Sarcopenia is in general known to be associate...

    Authors: Derrick A. Doolittle, Matthew C. Hernandez, Francis I. Baffour, Michael R. Moynagh, Naoki Takahashi, Adam T. Froemming, Katrina N. Glazebrook and Brian D. Kim
    Citation: European Radiology Experimental 2021 5:9
    Content type: Original article Published on:

  44. Colonic manometry is the current reference standard for assessing colonic neuromuscular function in children with intractable functional constipation (FC). Recently, cine magnetic resonance imaging (cine-MRI) ...

    Authors: M. H. Vriesman, C. S. de Jonge, S. Kuizenga-Wessel, B. Adler, A. Menys, A. J. Nederveen, J. Stoker, M. A. Benninga and C. Di Lorenzo
    Citation: European Radiology Experimental 2021 5:8
    Content type: Original article Published on:

  45. We aimed to train and test a deep learning classifier to support the diagnosis of coronavirus disease 2019 (COVID-19) using chest x-ray (CXR) on a cohort of subjects from two hospitals in Lombardy, Italy.

    Authors: Isabella Castiglioni, Davide Ippolito, Matteo Interlenghi, Caterina Beatrice Monti, Christian Salvatore, Simone Schiaffino, Annalisa Polidori, Davide Gandola, Cristina Messa and Francesco Sardanelli
    Citation: European Radiology Experimental 2021 5:7
    Content type: Original article Published on:

  46. Grating-based x-ray dark-field and phase-contrast imaging allow extracting information about refraction and small-angle scatter, beyond conventional attenuation. A step towards clinical translation has recentl...

    Authors: Jana Andrejewski, Fabio De Marco, Konstantin Willer, Wolfgang Noichl, Alex Gustschin, Thomas Koehler, Pascal Meyer, Fabian Kriner, Florian Fischer, Christian Braun, Alexander A. Fingerle, Julia Herzen, Franz Pfeiffer and Daniela Pfeiffer
    Citation: European Radiology Experimental 2021 5:6
    Content type: Original article Published on:

  47. Average Hausdorff distance is a widely used performance measure to calculate the distance between two point sets. In medical image segmentation, it is used to compare ground truth images with segmentations all...

    Authors: Orhun Utku Aydin, Abdel Aziz Taha, Adam Hilbert, Ahmed A. Khalil, Ivana Galinovic, Jochen B. Fiebach, Dietmar Frey and Vince Istvan Madai
    Citation: European Radiology Experimental 2021 5:4
    Content type: Methodology Published on:

    The Correction to this article has been published in European Radiology Experimental 2022 6:56

  48. To evaluate robustness and repeatability of magnetic resonance imaging (MRI) texture features in water and tissue phantom test-retest study.

    Authors: Joshua Shur, Matthew Blackledge, James D’Arcy, David J. Collins, Maria Bali, Martin O’Leach and Dow-Mu Koh
    Citation: European Radiology Experimental 2021 5:2
    Content type: Original article Published on:

  49. This review describes a cellular adaptive stress signalling roadmap connecting the 1H magnetic resonance spectroscopy (MRS) total choline peak at 3.2 ppm (tCho) to cancer response after targeted therapy (TT). Rec...

    Authors: Egidio Iorio, Franca Podo, Martin O. Leach, Jason Koutcher, Francis G. Blankenberg and Joseph F. Norfray
    Citation: European Radiology Experimental 2021 5:5
    Content type: Narrative review Published on:

  50. The detection and assessment of cerebral lesions and traumatic brain injuries are of particular interest in forensic investigations in order to differentiate between natural and traumatic deaths and to reconst...

    Authors: Dominic Gascho, Niklaus Zoelch, Stefan Sommer, Carlo Tappero, Michael J. Thali and Eva Deininger-Czermak
    Citation: European Radiology Experimental 2021 5:3
    Content type: Technical note Published on:
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