McCormick PA, Dick R, Graffeo M et al (1990) The effect of non-protein liquid meals on the hepatic venous pressure gradient in patients with cirrhosis. J Hepatol 11:221–225
Article
PubMed
CAS
Google Scholar
Albillos A, Bañares R, González M et al (2007) The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis. Gut 56:259–264
Article
PubMed
CAS
Google Scholar
Vorobioff JD, Gamen M, Kravetz D et al (2002) Effects of long-term propranolol and octreotide on postprandial hemodynamics in cirrhosis: a randomized, controlled trial. Gastroenterology 122:916–922
Article
PubMed
CAS
Google Scholar
Tsunoda T, Ohnishi K, Tanaka H (1988) Portal hemodynamic responses after oral intake of glucose in patients with cirrhosis. Am J Gastroenterol 83:398–403
PubMed
CAS
Google Scholar
Sabbá C, Ferraioli G, Genecin P et al (1991) Evaluation of postprandial hyperemia in superior mesenteric artery and portal vein in healthy and cirrhotic humans: an operator-blind echo-Doppler study. Hepatology 13:714–718
Article
PubMed
Google Scholar
Ludwig D, Schwarting K, Korbel CM et al (1998) The postprandial portal flow is related to the severity of portal hypertension and liver cirrhosis. J Hepatol 28:631–638
Article
PubMed
CAS
Google Scholar
Sacerdoti D, Gaiani S, Buonamico P et al (1997) Interobserver and interequipment variability of hepatic, splenic, and renal arterial Doppler resistance indices in normal subjects and patients with cirrhosis. J Hepatol 27:986–992
Article
PubMed
CAS
Google Scholar
Sabbá C, Weltin GG, Cicchetti DV et al (1990) Observer variability in echo-Doppler measurements of portal flow in cirrhotic patients and normal volunteers. Gastroenterology 98:1603–1611
Article
PubMed
Google Scholar
Barbaro B, Palazzoni G, Prudenzano R et al (1999) Doppler sonographic assessment of functional response of the right and left portal venous branches to a meal. J Clin Ultrasound 27:75–80
Article
PubMed
CAS
Google Scholar
Jajamovich GH, Dyvorne H, Donnerhack C, Taouli B (2014) Quantitative liver MRI combining phase contrast imaging, elastography, and DWI: assessment of reproducibility and postprandial effect at 3.0 T. PLoS One 9:e97355
Article
PubMed
PubMed Central
CAS
Google Scholar
Gouya H, Vignaux O, Sogni P et al (2011) Chronic liver disease: systemic and splanchnic venous flow mapping with optimized cine phase-contrast MR imaging validated in a phantom model and prospectively evaluated in patients. Radiology 261:144–155
Article
PubMed
Google Scholar
Yzet T, Bouzerar R, Allart JD et al (2010) Hepatic vascular flow measurements by phase contrast MRI and doppler echography: a comparative and reproducibility study. J Magn Reson Imaging 31:579–588
Stankovic Z (2016) Four-dimensional flow magnetic resonance imaging in cirrhosis. World J Gastroenterol 22:89–102
Article
PubMed
PubMed Central
CAS
Google Scholar
Roldán-Alzate A, Frydrychowicz A, Niespodzany E et al (2013) In vivo validation of 4D flow MRI for assessing the hemodynamics of portal hypertension. J Magn Reson Imaging 37:1100–1108
Article
PubMed
Google Scholar
Stankovic Z, Jung B, Collins J et al (2014) Reproducibility study of four-dimensional flow MRI of arterial and portal venous liver hemodynamics: influence of spatio-temporal resolution. Magn Reson Med 72:477–484
Article
PubMed
Google Scholar
Roldán-Alzate A, Frydrychowicz A, Said A et al (2015) Impaired regulation of portal venous flow in response to a meal challenge as quantified by 4D flow MRI. J Magn Reson Imaging 42:1009–1017
Article
PubMed
PubMed Central
Google Scholar
Arena U, Lupsor Platon M, Stasi C et al (2013) Liver stiffness is influenced by a standardized meal in patients with chronic hepatitis C virus at different stages of fibrotic evolution. Hepatology 58:65–72
Article
PubMed
CAS
Google Scholar
Yin M, Talwalkar JA, Glaser KJ et al (2011) Dynamic postprandial hepatic stiffness augmentation assessed with MR elastography in patients with chronic liver disease. AJR Am J Roentgenol 197:64–70
Article
PubMed
PubMed Central
Google Scholar
Miyajima H, Nomura M, Muguruma N et al (2001) Relationship among gastric motility, autonomic activity, and portal hemodynamics in patients with liver cirrhosis. J Gastroenterol Hepatol 16:647–659
Article
PubMed
CAS
Google Scholar
Sugano S, Yamamoto K, Takamura N, Momiyama K, Watanabe M, Ishii K (1999) Azygos venous blood flow while fasting, postprandially, and after endoscopic variceal ligation, measured by magnetic resonance imaging. J Gastroenterol 34:310–314
Schalkx HJ, Petersen ET, Peters NH et al (2015) Arterial and portal venous liver perfusion using selective spin labelling MRI. Eur Radiol 25:1529–1540
Pazahr S, Nanz D, Rossi C et al (2014) Magnetic resonance imaging of the liver: apparent diffusion coefficients from multiexponential analysis of b values greater than 50 s/mm2 do not respond to caloric intake despite increased portal-venous blood flow. Investig Radiol 49:138–146
Article
CAS
Google Scholar
O'Brien S, Keogan M, Patchett S, McCormick PA, Afdhal N, Hegarty JE (1992) Postprandial changes in portal haemodynamics in patients with cirrhosis. Gut 33:364–367
Numata K, Tanaka K, Kiba T et al (1999) Hepatic arterial resistance after mixed-meal ingestion in healthy subjects and patients with chronic liver disease. J Clin Ultrasound 27:239–248
Article
PubMed
CAS
Google Scholar
Dauzat M, Lafortune M, Patriquin H, Pomier-Layrargues G (1994) Meal induced changes in hepatic and splanchnic circulation: a noninvasive Doppler study in normal humans. Eur J Appl Physiol Occup Physiol 68:373–380
Article
PubMed
CAS
Google Scholar
de Vries PJ, de Hooge P, Hoekstra JB, van Hattum J (1994) Blunted postprandial reaction of portal venous flow in chronic liver disease, assessed with duplex Doppler: significance for prognosis. J Hepatol 21:966–973
Article
PubMed
CAS
Google Scholar
Ozdogan O, Atalay H, Cimsit C et al (2008) Role of echo Doppler ultrasonography in the evaluation of postprandial hyperemia in cirrhotic patients. World J Gastroenterol 14:260–264
Zafra C, Abraldes JG, Turnes J et al (2004) Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis. Gastroenterology 126:749–755
Article
PubMed
CAS
Google Scholar
Zardi EM, Dobrina A, Uwechie V et al (2008) Postmeal portal flow variations in HCV-related chronic hepatitis and liver cirrhosis with and without hyperdynamic syndrome. In Vivo 22:509–512
Krag A, Simonsen L, Henriksen JH, Ottesen L, Bendtsen F (2006) Effect of meal and propranolol on whole body and splanchnic oxygen consumption in patients with cirrhosis. Am J Physiol Gastrointest Liver Physiol 291:G8–G15
Rosenberg WM, Voelker M, Thiel R et al (2004) Serum markers detect the presence of liver fibrosis: a cohort study. Gastroenterology 127:1704–1713
Liss P, Cox EF, Eckerbom P, Francis ST (2013) Imaging of intrarenal haemodynamics and oxygen metabolism. Clin Exp Pharmacol Physiol 40:158–167
Article
PubMed
CAS
Google Scholar
Günther M, Bock M, Schad LR (2001) Arterial spin labeling in combination with a look-locker sampling strategy: inflow turbo-sampling EPI-FAIR (ITS-FAIR). Magn Reson Med 46:974–984
Article
PubMed
Google Scholar
Francis ST, Bowtell R, Gowland PA (2008) Modeling and optimization of look-locker spin labeling for measuring perfusion and transit time changes in activation studies taking into account arterial blood volume. Magn Reson Med 59:316–325
Article
PubMed
CAS
Google Scholar
Lichtinghagen R, Pietsch D, Bantel H, Manns MP, Brand K, Bahr MJ (2013) The enhanced liver fibrosis (ELF) score: normal values, influence factors and proposed cut-off values. J Hepatol 59:236–242
Conti F, Vukotic R, Foschi FG et al (2016) Transient elastography in healthy subjects and factors influencing liver stiffness in non-alcoholic fatty liver disease: an Italian community-based population study. Dig Liver Dis 48:1357–1363
Article
PubMed
Google Scholar
Bradley CR, Cox EF, Scott R et al (2018) Multi organ assessment of compensated cirrhosis patients using quantitative magnetic resonance imaging. J Hepatol https://doi.org/10.1016/j.jhep.2018.05.037
Khoo EYH, Stevenson MC, Leverton E et al (2012) Elevation of alanine transaminase and markers of liver fibrosis after a mixed meal challenge in individuals with type 2 diabetes. Dig Dis Sci 57:3017–3025
Article
PubMed
CAS
Google Scholar
Gaiani S, Bolondi L, Li Bassi S, Santi V, Zironi G, Barbara L (1989) Effect of meal on portal hemodynamics in healthy humans and in patients with chronic liver disease. Hepatology 9:815–819
Bellamy EA, Bossi MC, Cosgrove DO (1984) Ultrasound demonstration of changes in the normal portal venous system following a meal. Br J Radiol 57:147–149
Article
PubMed
CAS
Google Scholar
Okazaki K, Miyazaki M, Onishi S, Ito K (1986) Effects of food intake and various extrinsic hormones on portal blood flow in patients with liver cirrhosis demonstrated by pulsed Doppler with the Octoson. Scand J Gastroenterol 21:1029–1038
Article
PubMed
CAS
Google Scholar
Joynt LK, Platt JF, Rubin JM, Ellis JH, Bude RO (1995) Hepatic artery resistance before and after standard meal in subjects with diseased and healthy livers. Radiology 196:489–492
Alústiza Echeverría JM, Castiella A, Emparanza JI (2012) Quantification of iron concentration in the liver by MRI. Insights Imaging 3:173–180
Article
PubMed
Google Scholar
Haque M, Koktzoglou I, Li W, Carbray J, Prasad P (2010) Functional MRI of liver using BOLD MRI: effect of glucose. J Magn Reson Imaging 32:988–991
Kamada T, Hayashi N, Sato N, Kasahara A, Abe H (1986) Estimated hepatic oxygen consumption in patients with chronic liver diseases as assessed by organ reflectance spectrophotometry. Dig Dis Sci 31:119–124
Gülberg V, Haag K, Rössle M, Gerbes AL (2002) Hepatic arterial buffer response in patients with advanced cirrhosis. Hepatology 35:630–634
Article
PubMed
Google Scholar
Bellis L, Berzigotti A, Abraldes JG et al (2003) Low doses of isosorbide mononitrate attenuate the postprandial increase in portal pressure in patients with cirrhosis. Hepatology 37:378–384
Article
PubMed
CAS
Google Scholar
Hernández-Guerra M, García-Pagán JC, Turnes J et al (2006) Ascorbic acid improves the intrahepatic endothelial dysfunction of patients with cirrhosis and portal hypertension. Hepatology 43:485–491
Article
PubMed
CAS
Google Scholar
Acalovschi M, Dumitraşcu DL, Csakany I (1997) Gastric and gall bladder emptying of a mixed meal are not coordinated in liver cirrhosis--a simultaneous sonographic study. Gut 40:412–417
Article
PubMed
PubMed Central
CAS
Google Scholar
Galati JS, Holdeman KP, Dalrymple GV, Harrison KA, Quigley EM (1994) Delayed gastric emptying of both the liquid and solid components of a meal in chronic liver disease. Am J Gastroenterol 89:708–711
Kalaitzakis E, Sadik R, Holst JJ, Ohman L, Björnsson E (2009) Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis. Clin Gastroenterol Hepatol 7:346–352