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Table 3 Baseline magnetic resonance imaging flow, perfusion, and transverse relaxation time (T2*) data for healthy participants and patients with compensated cirrhosis (CC)

From: MRI assessment of altered dynamic changes in liver haemodynamics following a meal challenge in compensated cirrhosis

Parameter Healthy subjects (HS) Compensated cirrhosis (CC) Baseline HS versus CC
p value
ICC
Baseline CoV (%) Baseline CoV (%)
Portal vein Area (mm2) 94.4 ± 25.5 7.3 ± 4.4 138.5 (92.4–141.7) 3.8 ± 2.6 0.063 0.984
Velocity (cm/s) 13.2 ± 2.7 9.4 ± 7.6 13.7 ± 2.9 4.9 (4.2–5.6) 0.694 0.924
Flux (mL/s) 12.0 ± 3.1 6.8 (5.7–11.0) 16.3 ± 4.5 5.7 ± 1.9 0.022a 0.979
Hepatic artery Area (mm2) 24.6 ± 4.8 5.5 (3.9–7.9) 20.7 (19.8–23.4) 5.7 (2.7–8.5) 0.278 0.942
Velocity (cm/s) 18.0 ± 3.5 9.4 (7.8–19.4) 16.2 (11.5–24.2) 7.9 ± 3.5 0.720 0.985
Flux (mL/s) 4.5 ± 1.5 15.4 ± 8.5 3.5 (2.8–5.0) 7.5 ± 4.5 0.315 0.975
Total hepatic blood flow (mL/s) 16.2 ± 4.1 8.4 (5.6–9.5) 20.9 ± 5.0 5.5 ± 3.6 0.038a 0.972
Azygos vein Area (mm2) 21.6 ± 6.3 6.0 (4.3–7.4) 20.8 (18.7–33.1) 2.5 (1.0–3.5) 0.635 0.985
Velocity (cm/s) 10.1 ± 4.9 9.3 ± 4.4 13.4 ± 3.7 7.1 ± 5.0 0.144 0.977
Flux (mL/s) 2.0 ± 0.6 14.7 ± 9.7 2.9 (2.3–5.0) 8.5 ± 5.2 0.042a 0.994
Liver perfusion (mL/100 g/min) 212.9 ± 53.9 11.2 ± 12.5 219.6 ± 75.5 12.5 ± 9.1 0.826 0.773
Arrival time of blood to liver (ms) 545 (499–604) 17.1 (4.9–41.3) 367 ± 89 26.1 ± 17.2 0.034a 0.793
T2* (ms) Mode 17.8 ± 3.7 2.5 ± 1.3 14.5 ± 5.3 1.4 (1.3–2.7) 0.126 0.996
FWHM 8.8 ± 2.3 4.4 (3.8–6.1) 7.8 ± 2.1 13.1 ± 10.1 0.294 0.930
  1. Data are mean ± standard deviation for normally distributed data or median and interquartile range for non-normally distributed data
  2. CoV coefficient of variation, ICC intra-class correlation (ICC)
  3. aStatistical significance