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Table 1 Standardised protocol for brain MRI

From: Ultra-high-field 7-T MRI in multiple sclerosis and other demyelinating diseases: from pathology to clinical practice

Brain MRI is important for achieving a prompt, accurate diagnosis of MS. Here we present a standardised protocol for the evaluation of patients with suspected or clinically definite MS; however, the precise sequences and timing of follow-up scans must be determined on a case-by-case basis
Baseline evaluation
 Mandatory sequences
  ▪ Axial proton-density and/or T2-FLAIR/T2-weighted
  ▪ Sagittal 2D or 3D T2-FLAIR
  ▪ 2D or 3D contrast-enhanced T1-weighted
 Optional sequences
  ▪ Unenhanced 2D or high-resolution isotropic 3D T1-weighted
  ▪ 2D and/or 3D dual inversion recovery
  ▪ Axial diffusion-weighted imaging
Follow-up examinations
 Mandatory sequences
  ▪ Axial proton-density and/or T2-Flair/T2-weighted highly recommended
  ▪ 2D or 3D contrast-enhanced T1-weighted
 Optional sequences
  ▪ Unenhanced 2D or high-resolution isotropic 3D T1-weighted
  ▪ 2D and/or 3D dual inversion recovery
  ▪ Axial diffusion-weighted imaging
  1. Abbreviation: FLAIR Fluid-attenuated inversion recovery, MS Multiple sclerosis