European Radiology Experimental

Table 5 Intra- and interobserver agreement of diffusion-weighted imaging parameters in 22 tumor models

From: Multi-b-value DWI to evaluate the synergistic antiproliferation and anti-heterogeneity effects of bufalin plus sorafenib in an orthotopic HCC model

	Intraobserver^a			Interobserver
	ICC	95% CI	p	ICC	95% CI	p
D_t	0.987	0.969–0.995	< 0.001	0.990	0.975–0.996	< 0.001
D_p	0.989	0.974–0.995	< 0.001	0.978	0.943–0.991	< 0.001
f	0.945	0.871–0.977	< 0.001	0.937	0.854–0.973	< 0.001
Mean diffusivity	0.992	0.979–0.997	< 0.001	0.990	0.977–0.996	< 0.001
Mean kurtosis	0.984	0.962–0.993	< 0.001	0.983	0.959–0.993	< 0.001
Distributed diffusion coefficient	0.986	0.966–0.994	< 0.001	0.983	0.957–0.993	< 0.001
α	0.973	0.936–0.988	< 0.001	0.966	0.922–0.986	< 0.001
D	0.988	0.970–0.995	< 0.001	0.981	0.955–0.992	< 0.001
β	0.984	0.962–0.993	< 0.001	0.976	0.944–0.990	< 0.001
µ	0.979	0.950–0.991	< 0.001	0.930	0.842–0.970	< 0.001

^aA radiologist with 19 years of experience in liver magnetic resonance imaging interpretation. CI Confidence interval, ICC Intraclass correlation coefficient

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