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Table 4 Comparisons of diffusion-weighted imaging and histopathological results among four groups

From: Multi-b-value DWI to evaluate the synergistic antiproliferation and anti-heterogeneity effects of bufalin plus sorafenib in an orthotopic HCC model

Parameters

Groups

(BS)-(B)

(BS)-(S)

(BS)-(C)

(B)-(S)

(B)-(C)

(S)-(C)

Z

p†

Z

p†

Z

p†

Z

p†

Z

p†

Z

p†

Necrotic fraction

-1.685

0.552

-1.393

0.982

-2.812

0.030

-0.230

1.000

-1.182

1.000

-1.357

1.000

Microvessel density

1.210

1.000

2.390

0.101

2.781

0.033

-1.286

1.000

1.648

0.597

0.284

1.000

Histopathological SD

0.907

1.000

2.581

0.059

3.281

0.006

-1.789

0.442

2.490

0.077

0.585

1.000

f

0.372

1.000

0.968

1.000

2.684

0.044

-0.640

1.000

2.425

0.092

1.673

0.566

Mean diffusivity

-1.000

1.000

-2.143

0.193

-2.823

0.029

1.238

1.000

-1.912

0.336

-0.585

1.000

Mean kurtosis

1.780

0.450

2.532

0.068

3.009

0.016

-0.865

1.000

1.289

1.000

0.365

1.000

α

-1.152

1.000

-1.929

0.322

-2.873

0.024

0.863

1.000

-1.806

0.426

-0.859

1.000

β

-1.500

0.801

-2.240

0.150

-2.984

0.017

0.839

1.000

-1.556

0.718

-0.644

1.000

  1. Significant results reported in bold characters. p† Mann-Whitney U test with Bonferroni adjustment. B Bufalin treatment, BS Bufalin plus sorafenib treatment, C Control, S Sorafenib treatment, SD Standard deviation