European Radiology Experimental

Table 3 Comparisons of histopathological results among four groups

From: Multi-b-value DWI to evaluate the synergistic antiproliferation and anti-heterogeneity effects of bufalin plus sorafenib in an orthotopic HCC model

Parameters (mean ± SD)	BS group (n = 5)	B group (n = 6)	S group (n = 5)	C group (n = 6)	χ²	p
Volume (cm³)	0.928 ± 0.186	1.072 ± 0.153	1.034 ± 0.125	1.208 ± 0.449	1.263	0.738
Necrotic fraction	0.330 ± 0.098	0.230 ± 0.093	0.226 ± 0.063	0.165 ± 0.068	7.965	0.047
Microvessel density	23.533 ± 2.036	26.333 ± 2.936	29.600 ± 4.991	30.167 ± 3.811	9.545	0.023
Histopathological SD	9.958 ± 0.945	10.719 ± 1.195	12.701 ± 0.866	13.901 ± 2.212	13.972	0.003

Significant results reported in bold characters. Data are expressed as mean ± SD. B Bufalin treatment, BS Bufalin plus sorafenib treatment, C control, S Sorafenib treatment, SD Standard deviation

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