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Table 2 Comparisons of diffusion-weighted imaging parameters among four groups

From: Multi-b-value DWI to evaluate the synergistic antiproliferation and anti-heterogeneity effects of bufalin plus sorafenib in an orthotopic HCC model

Parameters (mean ± SD)

BS group (n = 5)

B group (n = 6)

S group (n = 5)

C group (n = 6)

χ2

p

Dt(×10-3 mm2/s)

0.599 ± 0.116

0.530 ± 0.067

0.519 ± 0.068

0.475 ± 0.034

5.739

0.125

Dp(×10-3 mm2/s)

6.114 ± 3.782

9.071 ± 5.513

11.848 ± 5.092

13.988 ± 5.174

6.580

0.087

f

0.016 ± 0.009

0.018 ± 0.009

0.024 ± 0.017

0.038 ± 0.010

8.910

0.031

MD(×10-3 mm2/s)

0.695 ± 0.173

0.596 ± 0.094

0.534 ± 0.103

0.505 ± 0.038

9.502

0.023

MK

0.665 ± 0.132

0.903 ± 0.155

1.016 ± 0.191

1.020 ± 0.123

10.375

0.016

DDC(×10-3 mm2/s)

0.524 ± 0.079

0.459 ± 0.047

0.456 ± 0.067

0.420 ± 0.018

7.523

0.057

α

0.912 ± 0.023

0.887 ± 0.028

0.865 ± 0.046

0.853 ± 0.023

9.002

0.029

D(×10-3 mm2/s)

0.432 ± 0.043

0.399 ± 0.024

0.398 ± 0.047

0.390 ± 0.042

3.169

0.366

β

0.932 ± 0.026

0.906 ± 0.022

0.884 ± 0.036

0.871 ± 0.039

9.739

0.021

µ(μm)

5.962 ± 1.130

5.745 ± 0.766

5.766 ± 1.035

4.297 ± 1.540

6.795

0.079

  1. Significant results reported in bold characters. Data are expressed as mean ± SD. B Bufalin treatment, BS Bufalin plus sorafenib treatment, C Control, DDC Distributed diffusion coefficient, MD Mean diffusivity, MK Mean kurtosis, S Sorafenib treatment, SD Standard deviation