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European Radiology Experimental
Fig. 5 | European Radiology Experimental

Fig. 5

From: Hyperpolarized [1-13C]-pyruvate MRS evaluates immune potential and predicts response to radiotherapy in cervical cancer

Fig. 5

Hyperpolarized MR spectroscopy and imaging of the spleen before and after radiotherapy. The splenic hyperpolarized (HP) [1-13C]-lactate-to-tC ratio (%) revealed a 1.7-fold increase (b), and the splenic [1-13C]-alanine-to-tC ratio (%) revealed a 1.8-fold increase (c) after radiotherapy, albeit without statistical significance. There were no significant differences observed in the HP [13C]-pyruvate-to-tC ratio (a) and HP [.13C]-bicarbonate-to-tC ratio (d) as well as the splenic volume (e) or apparent diffusion coefficient (ADC) values (f)

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