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European Radiology Experimental
Fig. 3 | European Radiology Experimental

Fig. 3

From: Tumor suppression effect of ultrasound-sensitive nanoparticles with focused ultrasound in a pancreas cancer xenograft model

Fig. 3

Tumor growth rate in dose-response experiment. At doses 4 mg/kg or greater, the IMP301 with FUS group had significantly lower tumor growth rate, compared to the control, GEM, DOX with FUS, and 2 mg/kg IMP301 with FUS groups (p < 0.050; statistical significance indicated as asterisk, *). There was no significant difference between tumor growth rate among GEM, DOX with FUS, and 2 mg/kg IMP301 with FUS groups, but all three groups showed lower tumor growth rate than the control group (p < 0.050). DOX Doxil, FUS Focused ultrasound, GEM Gemcitabine, IMP301 Doxorubicin HCl-loaded liposome, IMP2 2 mg/kg IMP301, IMP4 4 mg/kg IMP301, IMP6 6 mg/kg IMP301, C Control

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