Table 2 Diagnostic testing accuracies
Accuracy | Sensitivity | Specificity | PPV | NPV | LR + | LR- | DOR | |
|---|---|---|---|---|---|---|---|---|
PneumOld-CT cohort | ||||||||
Clinicians (CXR) | 64.0% (57.1–70.3) | 76.7% (68.8–83.1) | 38.8% (28.0–50.8) | 71.3% (63.4–78.1) | 45.6% (33.4–58.4) | 1.253 (0.956–1.688) | 0.601 (0.334–1.112) | 2.087 |
Radiol. 1 (CXR) | 75.5% (69.1–80.9) | 69.9% (61.7–77.1) | 86.6% (76.4–92.8) | 91.2% (84.1–95.3) | 59.2% (49.3–68.4) | 5.206 (2.613–10.658) | 0.347 (0.247–0.502) | 14.983 |
Radiol. 2 (CXR) | 71.0% (64.4–76.8) | 67.7% (59.3–75.0) | 77.6% (66.3–85.9) | 85.7% (77.8–91.1) | 54.7% (44.7–64.4) | 3.023 (1.760–5.335) | 0.417 (0.291–0.614) | 7.256 |
AI (CXR) | 71.0% (64.4–76.8) | 74.4% (66.4–81.1) | 64.2% (52.2–74.6) | 80.5% (72.6–86.5) | 55.8% (44.7–66.4) | 2.078 (1.390–3.193) | 0.398 (0.253–0.643) | 5.217 |
LDCT | 79.0% (72.8–84.1) | 72.9% (64.8–79.8) | 91.0% (81.8–95.8) | 94.2% (87.9–97.3) | 62.9% (53.0–71.8) | 8.144 (3.563–19.131) | 0.297 (0.211–0.430) | 27.394 |
PACSCAN cohort | ||||||||
Clinicians (CXR) | 63.0% (56.6–69.0) | 61.4% (53.2–69.1) | 65.6% (55.3–74.6) | 73.5% (64.9–80.7) | 52.2% (43.1–61.2) | 1.783 (1.189–2.715) | 0.588 (0.415–0.847) | 3.031 |
Radiol. (CXR) | 70.9% (64.7–76.4) | 67.9% (59.7–75.0) | 75.6% (65.8–83.3) | 81.2% (73.2–87.2) | 60.2% (51.0–68.7) | 2.776 (1.744–4.484) | 0.425 (0.300–0.612) | 6.525 |
AI (CXR) | 72.6% (66.5–78.0) | 72.1% (64.2–78.9) | 73.3% (63.4–81.4) | 80.8% (73.0–86.7) | 62.9% (53.3–71.5) | 2.705 (1.753–4.237) | 0.380 (0.259–0.565) | 7.122 |
CT (LDCT/full–dose) | 89.6% (84.9–92.9) | 87.1% (80.6–91.7) | 93.3% (86.2–96.9) | 95.3% (90.2–97.8) | 82.4% (73.8–88.5) | 13.071 (5.844–29.67) | 0.138 (0.086–0.225) | 94.889 |