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Table 2 MRI acquisition parameters of the core protocol. The table is a licensed copy of supplementary Table S1 of [2], distributed under copyright, and redistributed with Springer Nature License 5,624,870,209,763

From: Cerebral MRI in a prospective cohort study on depression and atherosclerosis: the BiDirect sample, processing pipelines, and analysis tools

Sequence

Parameters

In-plane resolution

Slices

TR (ms)

TE (ms)

Tl (ms)

FA

Matrix

FOV (mm × mm)

Reconstructed (mm × mm)

n

Thickness (mm)

Gap (mm)

Orientation

2D T2 *w gradient-echo (FFE)

574

16

-

18°

256 × 164

230 × 183

0.45 × 0.45

27

4

1

Axial

2D fast dark fluid imaging (TSE-FLAIR)

11,000

120

2,600

90°

352 × 206

230 × 186

0.45 × 0.45

27

4

1

Axial

2D T2w fast spin-echo (TSE)a

3,000

80

-

90°

400 × 255

230 × 184

0.45 × 0.45

27

4

1

Axial

3D T1w gradient-echo sequence with inversion prepulse (3D TFE)

7.26

3.56

404

256 × 256

256 × 256

1.00 × 1.00

160

b) 2

-

Sagittal

2D diffusion-weighted sequence with echo-planar imaging (single-shot SE-EPI)c

5,900

95

-

90°

128 × 128

240 × 240

0.94 × 0.94

36

3.6

-

Axial

Stimulation-based fMRI sequence with echo planar imaging (single-shot FFE-EPI), 82 volumes after 5 dummy scansd

2,200

30

-

90°

64 × 64

230 × 230

3.60 × 3.60

35

3.6

-

Axial

Resting-state fMRI sequence with echo planar imaging (single-shot FFE-EPI), 72 volumes after 5 dummy scanse

3,000

38

-

90°

64 × 64

230 × 230

3.60 × 3.60

36

3.6

-

Axial

  1. TR Repetition time, TE Echo time, TI Inversion time, FA Flip angle, FOV Field of view, fMRI Functional magnetic resonance imaging
  2. a1st follow-up examination and beyond
  3. bReconstructed by zero filling in k-space to 1-mm slice thickness
  4. c20 gradient directions with b value of 1,000 s/mm2; reference b value is 0 s/mm2
  5. dBaseline examination only. The emotion processing task is a short version of a previously published fMRI paradigm investigating neural responsiveness to happy and sad facial expressions in patients with major depression [1,2,3]. Facial stimuli consist of happy, sad, and neutral expressions according to Ekman and Friesen [4]. The passive viewing task with a presentation time of 3 min is subdivided into 6 blocks of 30 s each. During the first 20 s of a block, facial stimuli falling in the same category are presented for 500 ms each in a random sequence. The remaining 10 s of a block serve as no-face epoch. The order of blocks is sad-neutral-happy-sad-neutral-happy
  6. ePrior to this sequence participants were instructed to remain motionless, mainly keep their eyes open, not to fall asleep, and not to think of anything in particular