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Table 3 Per-lesion diagnostic performance and area under the curve of MRI analyzed by both the more and the less experienced readers for the definition of UTUC infiltration of muscular layer and perivisceral fat tissue

From: MRI for risk stratification of muscle invasion by upper tract urothelial carcinoma: a feasibility study

  

Sensitivity % (95% CI)

Specificity % (95% CI)

PPV % (95% CI)

NPV % (95% CI)

Accuracy % (95% CI)

AUC (95% CI)

UTUC muscle invasion

More experienced reader

95 (82–100)

71 (47–88)

81 (63–93)

92 (70/100)

85 (67–96)

0.84 (0.70−0.98)

Less experienced reader

81 (61–94)

61 (38–81)

71 (51–86)

73 (48–91)

72 (55–83)

0.71 (0.54−0.88)

UTUC infiltration of perivisceral fat tissue

More experienced reader

87 (56–99)

93 (81–99)

78 (46–96)

97 (86–100)

92 (72–100)

0.91 (0.76−1.00)

Less experienced reader

78 (46–96)

87 (72–96)

64 (35–87)

93 (80–99)

85 (69–97)

0.86 (0.70−1.00)

  1. AUC Area under the curve, CI Confidence interval, MRI Magnetic resonance imaging, NPV Negative predictive value, PPV Positive predictive value, UTUC Upper tract urothelial carcinoma