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Table 2 Group mean and standard deviation of glucoCEST/DGE, difference of magnetization transfer effect and B0 shift for different regions of interest in the brain

From: Improved postprocessing of dynamic glucose-enhanced CEST MRI for imaging brain metastases at 3 T

Static

 

White matter

Grey matter

Cerebrospinal fluid

Sagittal sinus

glucoCEST (@1.2 ppm)

-0.34% ± 0.60%

-0.73% ± 0.98%

-0.99% ± 1.24%

-0.29% ± 1.83%

glucoCEST (@2 ppm)

-0.43% ± 0.78%

-0.80% ± 0.11%

-1.01% ± 1.28%

-1.48% ± 2.32%

δmagnetization transfera

-0.46% ± 0.88%

-0.29% ± 0.71%

-0.62% ± 1.42%

-0.39% ± 2.59%

δB0 shift (10−2 ppm) a

-1.84 ± 4.07

-2.88 ± 3.54

-1.44 ± 3.93

-2.00 ± 8.75

Dynamic

DGE (@2 ppm)

White matter

Grey matter

Cerebrospinal fluid

Sagittal sinus

DGEblock2, before

-0.10% ± 0.06%

-0.10% ± 0.07%

-0.10% ± 0.11%

-1.29% ± 1.10%

DGEblock2, after

-0.01% ± 0.14%

-0.09% ± 0.06%

-0.01% ± 0.19%

-1.11% ± 1.00%

DGEblock3, before

-0.14% ± 0.12%

-0.24% ± 0.03%

-0.18% ± 0.17%

-2.67% ± 1.57%

DGEblock3, after

-0.07% ± 0.21%

-0.24% ± 0.02%

-0.10% ± 0.34%

-2.44% ± 1.55%

DGEblock4, before

-0.05% ± 0.09%

-0.13% ± 0.05%

-0.14% ± 0.27%

-2.61% ± 1.85%

DGEblock4, after

-0.05% ± 0.10%

-0.16% ± 0.02%

-0.10% ± 0.22%

-2.50% ± 1.66%

  1. CEST Chemical exchange saturation transfer, DGE Dynamic glucose-enhanced
  2. aThe difference of the magnetization transfer effect and B0 shift was calculated by using the value from the static postinfusion scan minus that from the static baseline scan