Fig. 1

Data acquisition pipeline. Each volunteer was scanned statically by acquisition of a CEST sequence with a full Z-spectrum. Between the static scans, dynamic CEST imaging was obtained at two offsets (1.2 and 2.0 ppm). During the dynamic scan, glucose (50 mL 50% D-glucose [25 g] in 3:20 min:s) was administered, and venous blood samples were collected. CEST Chemical exchange saturation transfer