Association between thoracic and third lumbar CT-derived muscle mass and density in Caucasian patients without chronic disease: a proof-of-concept study

Brath, Mia Solholt Godthaab; Sahakyan, Marina; Mark, Esben Bolvig; Frøkjær, Jens Brøndum; Rasmussen, Henrik Højgaard; Østergaard, Lasse Riis; Weinreich, Ulla Møller

doi:10.1186/s41747-023-00340-1

European Radiology Experimental

Table 1 The skeletal muscle area, skeletal muscle index, and skeletal muscle density

From: Association between thoracic and third lumbar CT-derived muscle mass and density in Caucasian patients without chronic disease: a proof-of-concept study

		Females			Males			p-value
	Level	Number	Median	95% CI	Number	Median	95% CI	p-value
SMA (cm²)	T2	10	188.5	150.1–200.0	11	314.7	222.3–385.7	0.0001
	T3	10	176.6	128.8–209.2	11	298.3	195.6–350.3	0.0002
	T4	10	157.2	116.0–192.7	11	270.3	178.8–319.2	0.0002
	T5	10	141.2	102.9–168.6	11	242.6	152.4–296.2	0.0003
	T6	10	127.4	86.0–148.3	11	215.0	132.3–273.1	0.0003
	T7	10	107.2	69.4–127.9	11	177.2	107.1–228.1	0.0004
	T8	10	88.6	56.5–106.3	11	142.6	82.1–189.2	0.0006
	T9	10	70.2	46.5–90.0	11	126.7	82.3–165.7	0.0003
	T10	10	69.3	53.0–81.9	11	119.9	74.9–148.6	0.0002
	T11	9	64.9	52.7–80.3	11	115.5	72.2–155.4	0.0003
	T12	10	62.6	57.1–80.6	11	121.7	76.7–157.2	0.0001
	L3	10	117.1	111.3–144.2	11	202.1	139.0–225.3	0.0002
SMI (cm²/m²)	T2	10	70.4	57.2–73.5	11	97.8	70.2–119.0	0.0004
	T3	10	66.7	49.1–74.1	11	90.1	61.7–107.4	0.0007
	T4	10	59.2	44.2–68.3	11	79.1	56.4–97.3	0.0006
	T5	10	54.3	39.2–59.7	11	72.4	48.1–88.2	0.0009
	T6	10	48.6	32.8–52.5	11	64.9	41.8–78.9	0.0009
	T7	10	39.4	26.4–46.9	11	56.5	33.8–66.7	0.0015
	T8	10	32.7	21.5–39.0	11	45.1	25.9–54.7	0.0015
	T9	10	26.8	17.7–31.9	11	38.7	26.0–47.9	0.0012
	T10	10	24.8	19.8–29.0	11	37.1	24.0–45.3	0.0009
	T11	9	24.3	20.1–28.5	11	33.1	22.8–51.3	0.0012
	T12	10	23.8	19.8–28.6	11	37.6	24.2–45.3	0.0003
	L3	10	45.1	36.3–51.1	11	61.0	43.9–70.8	0.0006
SMD (mean HU)	T2	10	60.0	43.2–63.2	11	53.1	47.5–62.1	0.0486
	T3	10	60.1	46.4–64.5	11	52.4	47.3–61.5	0.0201
	T4	10	60.8	50.6–64.9	11	52.6	45.9–59.9	0.0015
	T5	10	60.2	49.3–65.5	11	51.4	40.6–56.6	0.0019
	T6	10	57.1	49.4–63.9	11	51.4	32.2–54.6	0.0008
	T7	10	54.8	48.9–62.2	11	47.0	30.9–54.9	0.0031
	T8	10	52.1	46.1–59.7	11	42.4	34.8–53.2	0.0060
	T9	10	53.7	47.0–59.5	11	43.9	32.2–56.4	0.0031
	T10	10	55.6	46.4–65.7	11	45.6	33.6–54.7	0.0006
	T11	9	56.3	45.4–61.9	11	45.5	34.3–57.1	0.0027
	T12	10	59.2	44.1–67.1	11	46.4	34.3–57.2	0.0011
	L3	10	59.6	42.5–72.7	11	50.0	40.1–60.1	0.0075

p-values are reported for the differences between males and females. CI Confidence interval, HU Hounsfield units, SMA Skeletal muscle area, SMD Skeletal muscle density, SMI Skeletal muscle index

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