Comparative assessment of coronary physiology using transthoracic pulsed-wave Doppler and myocardial contrast echocardiography in rats

European Radiology Experimental

Table 1 Hemodynamic and left ventricular parameters derived by transthoracic echocardiography at baseline and under stimulation with adenosine or dobutamine in eight rats

	Baseline		Adenosine			Dobutamine			p value²	η²
	Mean	SD	Mean	SD	p value¹	Mean	SD	p value¹	p value²	η²
HR (min^-1)	344	29	320	32	0.007	405	12	0.001	0.001	0.73
SBP (mmHg)	116	8	92	16	0.001	112	13	0.298	0.001	0.36
DBP (mmHg)	58	3	48	10	0.001	54	6	0.047	0.001	0.35
EDV (μL)	542	44	558	55	0.315	445	75	0.001	0.001	0.37
ESV (μL)	179	33	122	24	0.001	72	34	0.001	0.001	0.61
SV (μL)	375	41	433	40	0.001	371	50	0.414	0.001	0.24
EF (%)	68	5	78	4	0.001	83	4	0.001	0.001	0.53
CO (mL/min)	130	22	139	21	0.404	150	19	0.007	0.075	0.11

CO Cardiac output, DBP Diastolic blood pressure, EDV End-diastolic volume, EF Ejection fraction, ESV End-systolic volume, HR Heart rate, p value¹ Adenosine or dobutamine versus the baseline parameters, p value² Adenosine versus dobutamine, SBP Systolic blood pressure, SD Standard deviation, SV Stroke volume, η² Effect size