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Table 6 Correlation between triple-negative tumours and magnetic resonance imaging features

From: Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

   Triple negative χ2 analysis
p-value
Univariate analysis   Multivariate analysis  
     OR (CI 95%)a p-value OR (CI 95%)a p-value
No. of
patients
  37      
Tumour size Median (mm)
Range (mm)
23
9–90
     
 ≥ 2 cm   24/37 0.207 1.645 (0.756–3.577) 0.209   
T2 intensity Hypointensity
Isointensity
Hyperintensity
12/37
12/37
13/37
0.173 0.480 (0.218–1.056)
1.690 (0.737–3.875)
1.401 (0.630–3.116)
0.068
0.215
0.409
  
Mass enhancement   30/37 0.967 1.020 (0.392–2.655) 0.967   
Shape
(Mass)
Round
Oval
Irregular
26/30
0/30
4/30
0.001 7.150 (2.295–22.28)
Out of scale
0.205 (0.066–0.640)
0.001
0.006
5.319 (1.425–19.85) 0.013
Rim
enhancement
  22/30 < 0.001 9.408 (3.613–24.50) < 0.001 9.155 (2.537–33.04) 0.001
Intralesional necrosis   27/37 < 0.001 5.559 (2.416–12.79) < 0.001 0.846 (0.214–3.340) 0.811
Perilesional
oedema
  30/37 < 0.001 5.844 (2.352–14.52) < 0.001 3.852 (1.092–13.59) 0.036
Abnormal lymph nodes   18/37 0.106 1.868 (0.871–4.003) 0.108   
Intensity-to-time curve Type I
Type II
Type III
3/37
10/37
24/37
0.969 0.931 (0.238–3.644)
1.111 (0.475–2.601
0.936 (0.426–2.059)
0.919
0.808
0.870
  
ADC value Very low
Low
Intermediate
24/32
7/32
1/32
0.106 2.264 (0.921–5.565)
0.388 (0.152–0.986)
2.968 (0.180–48.88)
0.075
0.047
0.447
4.762 (0.018–1277) 0.584
Extent of disease Unifocal
Multifocal
Multicentric
15/37
10/37
12/37
0.530 0.765 (0.358–1.638)
0.872 (0.377–2.017)
1.600 (0.701–3.654)
0.491
0.749
0.265
  
  1. aOR Odds ratio, CI Confidence interval, ADC Apparent diffusion coefficient