| |
Patients with known CAD
|
Patients with suspected CAD
|
Patients with high heart rates ≥ 75 bpm
|
Patients with low heart rates < 75 bpm
|
|---|
|
Reconstruction/performance
|
HSR
|
MSR
|
p-value
|
HSR
|
MSR
|
p-value
|
HSR
|
MSR
|
p-value
|
HSR
|
MSR
|
p-value
|
|---|
|
Area under the curvea
|
0.72 [0.57, 0.86]
|
0.62 [0.45, 0.79]
|
0.157
|
0.89 [0.77, 1.00]
|
0.80 [0.63, 0.97]
|
0.243
|
0.55 [0.33, 0.77]
|
0.54 [0.27, 0.81]
|
0.611
|
0.87 [0.78, 0.95]
|
0.70 [0.57, 0.83]
|
0.007
|
|
Sensitivity
|
86 (43/50) [73, 94]
|
62 (31/50) [47, 75]
|
0.001
|
100 (8/8) [63, 100]
|
100 (8/8) [63, 100]
|
1.000
|
90 (19/21) [70, 99]
|
86 (18/21) [64, 97]
|
0.999
|
86 (32/37) [71, 95]
|
57 (21/37) [39, 73]
|
0.003
|
|
Specificity
|
39 (7/18) [17, 64]
|
67 (12/18) [41, 87]
|
0.131
|
59 (10/17) [33, 82]
|
65 (11/17) [38, 86]
|
0.999
|
11 (1/9) [0, 48]
|
33 (3/9) [7, 70]
|
0.480
|
62 (16/26) [41, 80]
|
77 (20/26) [56, 91]
|
0.289
|
|
Positive predictive value
|
80 (43/54) [66, 89]
|
84 (31/37) [68, 94]
|
0.387
|
53 (8/15) [27, 79]
|
57 (8/14) [29, 82]
|
0.563
|
70 (19/27) [50, 86]
|
75 (18/24) [53, 90]
|
0.254
|
76 (32/42) [61, 88]
|
78 (21/27) [58, 91]
|
0.814
|
|
Negative predictive value
|
50 (7/14) [23, 77]
|
39 (12/31) [22, 58]
|
0.282
|
100 (10/10) [69, 100]
|
100 (11/11) [72, 100]
|
0.999
|
33 (1/3) [1, 91]
|
50 (3/6) [12, 88]
|
0.417
|
76 (16/21) [53, 92]
|
56 (20/36) [38, 72]
|
0.009
|
- Reference: ≥ 50% diameter vessel stenosis detected in quantitative invasive coronary angiography. Data are the results of consensus reading of two readers. Unless otherwise stated, data are percentages, data in parentheses are raw data, and data in brackets are 95% confidence intervals. The 95% confidence intervals were estimated for unclustered data (see reference [31]). aData are the area under the curve and data in brackets are 95% confidence intervals. bpm Beats per minute, CAD Coronary artery disease, CTP Computed tomography perfusion, HSR Halfscan reconstruction, MSR Multisegment reconstruction
