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Table 2 Virtual non-calcium computed tomography (CT) ability to depict traumatic bone marrow edema on dual-energy spine scans

From: Virtual non-calcium dual-energy CT: clinical applications

Authors, year [reference]

DECT platform

Number of patients

Qualitative analysis (sensitivity, specificity, accuracy)

Quantitative analysis cutoff (sensitivity, specificity, accuracy)

Reference standard

Spine site

Wang et al., 2020 [51]

DSCT

20

85%, 97%, 93%

-12 HU (95%, 86%, 98%)

MRI

T/L

Jeong et al., 2020 [52]

DSCT

31

83%, 99%, 99%

NA

MRI

T/L

Booz et al., 2020 [29]

DSCT

52

93%, 95%, 90%

-43 HU (85%, 95%, 97%)

MRI

S

Foti et al., 2019 [58]

DSCT

76

88%, 92%, 90%

cutoff NA (92%, 90%, 91%)

MRI

T/L

Diekhoff et al., 2019 [53]

SACT

70

72%, 70%, NA

NA

MRI

T/L

Frellessen et al., 2018 [45]

DSCT

51

96%, 96%, 98%

NA

MRI

T/L

Diekhoff et al., 2017 [57]

SACT

9

88%, 100%, NA

NA

MRI

T/L

Petristsch et al., 2017 [54]

DSCT

22

64%, 99%, 93%

-47 HU (92%, 82%, 84%)

MRI

L

Kaup et al., 2016 [55]

DSCT

49

90%, 90%, 95%

NA

MRI

T/L

Bierry et al., 2014 [10]

DSCT

20

84%, 97%, 95%

cutoff NA (85%, 82%, NA)

MRI

T/L

Wang et al., 201 3[27]

DSCT

63

NA

-80 HU (96%, 98%, 97%)

MRI

T/L

  1. DECT Dual-energy computed tomography, DSCT Dual-source computed tomography, SACT Sequential acquisition computed tomography, HU Hounsfield units, NA Not available, MRI Magnetic resonance imaging, T Thoracic, L Lumbar, S Sacral