European Radiology Experimental

Table 1 Absolute measurements of tumour volume and lung volume as measured by micro-CT, clinical CT, and MRI for all three treatment groups

From: Monitoring treatment effects in lung cancer-bearing mice: clinical CT and clinical MRI compared to micro-CT

			Micro-CT		Clinical CT		Clinical MRI
			T0	T1	T0	T1	T0	T1
Cisplatin (n = 10)	Lung volume (mL)	Mean	0.959	0.794	0.964	0.788	0.987	0.724
	Lung volume (mL)	SD	0.235	0.204	0.224	0.171	0.336	0.234
	Tumour volume (mL)	Mean	0.656	0.418	0.505	0.293	0.724	0.401
	Tumour volume (mL)	SD	0.291	0.180	0.244	0.148	0.398	0.225
PBS (n = 12)	Lung volume (mL)	Mean	0.724	1.284	0.688	1.220	0.599	1.346
	Lung volume (mL)	SD	0.157	0.305	0.172	0.243	0.166	0.287
	Tumour volume (mL)	Mean/median	0.301*	1.059	0.262	0.842	0.278	1.153
	Tumour volume (mL)	SD/IQR	0.240–0.610**	0.334	0.128	0.282	0.167	0.343
No treatment (n = 9)	Lung volume (mL)	Mean	1.087	1.597	1.080	1.497	0.988	1.736
	Lung volume (mL)	SD	0.238	0.289	0.198	0.269	0.230	0.235
	Tumour volume (mL)	Mean	0.782	1.298	0.594	1.119	0.683	1.576
	Tumour volume (mL)	SD	0.243	0.206	0.191	0.217	0.260	0.195

CT Computed tomography, IQR Interquartile range, MRI Magnetic resonance imaging, PBS Phosphate-buffered saline, SD Standard deviation, T0 Pretreatment, T1 Posttreatment. In case of non-normally distributed data, median (*) and IQR (**) are given instead and marked

Back to article page