Fig. 1
Images of mouse liver sample. a Control. (a-1) Masson trichrome stain of a control: no fibrosis and no steatosis; (a-2) acoustic impedance image: there is a nearly even distribution of yellow area and blue/green area; median acoustic impedance 1.74 × 106 kg/m2/s. b Simple steatosis. (b-1) Masson trichrome stain: no fibrosis with 40% fat deposition; (b-2) acoustic impedance image: the blue/green area is larger than the yellow area; median acoustic impedance 1.66 × 106 kg/m2/s. c Nonalcoholic steatohepatitis. (c-1) Masson trichrome stain: advanced fibrosis (F3 or F4) with 30% fat deposition; (c-2) acoustic impedance image: the blue/green area is dominant; median acoustic impedance 1.6 × 106 kg/m2/s