|
Feature
|
Lesions (mean ± standard deviation)
|
Normal tissue (mean ± standard deviation)
|
p value
|
AUC (95% confidence interval)
|
|---|
|
Entropy
|
5.48 ± 0.35
|
5.65 ± 0.24
|
< 0.00001 for all
|
0.67 (0.63–0.71)
|
|
Variance
|
153.53 ± 23.59
|
137.75 ± 20.12
|
0.70 (0.66–0.73)
|
|
Contrast
|
24.10 ± 9.87
|
40.10 ± 12.5
|
0.84 (0.81–0.87)
|
|
Correlation
|
0.88 ± 0.06
|
0.81 ± 0.06
|
0.80 (0.65–0.83)
|
|
Energy
|
3.4 × 10−3 ± 1.5 × 10−3
|
2.2 × 10−3 ± 0.7 × 10−3
|
0.83 (0.80–0.86)
|
|
Homogeneity
|
0.36 ± 0.05
|
0.33 ± 0.04
|
0.72 (0.69–0.76)
|
|
Contrast
|
26.43 ± 12.38
|
40.94 ± 13.41
|
0.80 (0.76–0.83)
|
|
Correlation
|
0.87 ± 0.06
|
0.81 ± 0.07
|
0.78 (0.74–0.82)
|
|
Energy
|
3.9 × 10−3 ± 1.4 × 10−3
|
2.6 × 10−3 ± 0.7 × 10−3
|
0.86 (0.82–0.88)
|
|
Homogeneity (GLCM)
|
0.36 ± 0.05
|
0.33 ± 0.04
|
0.71 (0.66–0.74)
|
|
GLN (GLCM)
|
78.42 ± 77.69
|
156.28 ± 104.76
|
0.79 (0.76–0.83)
|
|
RLN (GLCM)
|
1,870.43 ± 1,792.01
|
4,085.00 ± 2,628.83
|
0.82 (0.79–0.85)
|
|
LRHGE (GLCM)
|
1,706.53 ± 209.23
|
1,635.50 ± 197.26
|
0.61 (0.57–0.65)
|
|
SRE (GLRLM)
|
0.91 ± 0.02
|
0.92 ± 0.04
|
0.69 (0.65–0.73)
|
|
LRE (GLRLM)
|
1.47 ± 0.17
|
1.39 ± 0.12
|
0.65 (0.61–0.69)
|
|
GLN (GLRLM)
|
78.53 ± 77.67
|
156.36 ± 104.73
|
0.79 (0.76–0.83)
|
|
RLN (GLRLM)
|
1,871.42 ± 1,786.51
|
4,080.90 ± 2,622.01
|
0.82 (0.79–0.85)
|
|
LRHGE (GLRLM)
|
1,677.30 ± 196.74
|
1,598.70 ± 168.52
|
0.61 (0.57–0.65)
|
|
LZE
|
5.38 ± 3.34
|
4.07 ± 2.38
|
0.66 (0.62–0.70)
|
|
HGZE
|
1,221.08 ± 45.52
|
1,191.37 ± 86.03
|
0.67 (0.63–0.71)
|
- GLCM Grey-level co-occurrence matrix, GLN Grey-level non-uniformity, RLN Run length non-uniformity, LRHGE Long-run high grey-level emphasis, GLRLM Grey-level run length matrix, SRE Short-run emphasis, LRE Long-run emphasis, LZE Large zone emphasis, HGZE High grey-level zone emphasis
