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Table 2 Texture features that showed significantly different mean values comparing lesions (benign and malignant) versus normal tissue (fat and fibroglandular) and corresponding area under the curve (AUC)

From: Diagnostic performance of machine learning applied to texture analysis-derived features for breast lesion characterisation at automated breast ultrasound: a pilot study

Feature

Lesions (mean ± standard deviation)

Normal tissue (mean ± standard deviation)

p value

AUC (95% confidence interval)

Entropy

5.48 ± 0.35

5.65 ± 0.24

< 0.00001 for all

0.67 (0.63–0.71)

Variance

153.53 ± 23.59

137.75 ± 20.12

0.70 (0.66–0.73)

Contrast

24.10 ± 9.87

40.10 ± 12.5

0.84 (0.81–0.87)

Correlation

0.88 ± 0.06

0.81 ± 0.06

0.80 (0.65–0.83)

Energy

3.4 × 10−3 ± 1.5 × 10−3

2.2 × 10−3 ± 0.7 × 10−3

0.83 (0.80–0.86)

Homogeneity

0.36 ± 0.05

0.33 ± 0.04

0.72 (0.69–0.76)

Contrast

26.43 ± 12.38

40.94 ± 13.41

0.80 (0.76–0.83)

Correlation

0.87 ± 0.06

0.81 ± 0.07

0.78 (0.74–0.82)

Energy

3.9 × 10−3 ± 1.4 × 10−3

2.6 × 10−3 ± 0.7 × 10−3

0.86 (0.82–0.88)

Homogeneity (GLCM)

0.36 ± 0.05

0.33 ± 0.04

0.71 (0.66–0.74)

GLN (GLCM)

78.42 ± 77.69

156.28 ± 104.76

0.79 (0.76–0.83)

RLN (GLCM)

1,870.43 ± 1,792.01

4,085.00 ± 2,628.83

0.82 (0.79–0.85)

LRHGE (GLCM)

1,706.53 ± 209.23

1,635.50 ± 197.26

0.61 (0.57–0.65)

SRE (GLRLM)

0.91 ± 0.02

0.92 ± 0.04

0.69 (0.65–0.73)

LRE (GLRLM)

1.47 ± 0.17

1.39 ± 0.12

0.65 (0.61–0.69)

GLN (GLRLM)

78.53 ± 77.67

156.36 ± 104.73

0.79 (0.76–0.83)

RLN (GLRLM)

1,871.42 ± 1,786.51

4,080.90 ± 2,622.01

0.82 (0.79–0.85)

LRHGE (GLRLM)

1,677.30 ± 196.74

1,598.70 ± 168.52

0.61 (0.57–0.65)

LZE

5.38 ± 3.34

4.07 ± 2.38

0.66 (0.62–0.70)

HGZE

1,221.08 ± 45.52

1,191.37 ± 86.03

0.67 (0.63–0.71)

  1. GLCM Grey-level co-occurrence matrix, GLN Grey-level non-uniformity, RLN Run length non-uniformity, LRHGE Long-run high grey-level emphasis, GLRLM Grey-level run length matrix, SRE Short-run emphasis, LRE Long-run emphasis, LZE Large zone emphasis, HGZE High grey-level zone emphasis