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Table 3 Changes in perfusion parameters, RECIST-1.1 diameter, and tumour volume in patients with partial response, stable disease, and progressive disease (n = 53)

From: Evaluation of response to conventional chemotherapy and radiotherapy by perfusion computed tomography in non-small cell lung cancer (NSCLC)

  Partial response (n = 30) Stable disease (n = 20) Progressive disease (n = 3)
Baseline Control p value Baseline Control p value Baseline Control p value
Blood flow (mL/100 mL/min) 162.0 ± 78.8 154.7 ± 90.2 0.681 234.0 ± 199.0 195.3 ± 111.8 0.391 171.7 ± 146.2 170.41 ± 130.3 0.968
Blood volume (mL/100 mL) 8.1 ± 3.1 6.4 ± 3.0 0.006 9.3 ± 4.9 7.9 ± 3.7 0.137 7.3 ± 2.8 7.3 ± 4.8 0.975
Permeability (mL/100 mL/min) 15.5 ± 5.7 13.9 ± 8.3 0.307 17.8 ± 11.3 16.5 ± 10.2 0.709 18.3 ± 6.5 17.7 ± 9.6 0.809
Mean transit time (s) 7.1 ± 3.1 5.8 ± 2.4 0.031 6.4 ± 4.1 5.8 ± 2.3 0.456 7.8 ± 3.5 7.0 ± 3.6 0.465
RECIST-1.1 diameter (mm) 59.8 ± 23.7 41.0 ± 18.0 0.000 55.7 ± 23.4 53.3 ± 23.2 0.007 58.7 ± 20.4 65.0 ± 26.2 0.210
Tumour volume (cc) 120.2 ± 154.0 44.6 ± 59.8 0.000 90.4 ± 122.3 64.3 ± 108.0 0.006 93.3 ± 73.4 126.7 ± 97.6 0.145
  1. Significant p values are in bold
  2. RECIST Response evaluation criteria in solid tumours