Timing optimization of low-dose first-pass analysis dynamic CT myocardial perfusion measurement: validation in a swine model

European Radiology Experimental

Table 2 Low-dose peak acquisition simulation as compared to ideal peak acquisition

Protocol (n = 98)	Cardiac cycle difference from peak (beats, mean)	p value (comparison with the ideal peak)	RMSE (beats)
\( \frac{{\mathrm{T}}_{\mathrm{i}}}{2} \)+ 0.5 s	-0.56 ± 1.79	0.004	1.87
\( \frac{{\mathrm{T}}_{\mathrm{i}}}{2} \) + 1.0 s	0.13 ± 1.85	0.497	1.84
\( \frac{{\mathrm{T}}_{\mathrm{i}}}{2} \) + 1.5 s	0.86 ± 1.97	0.000	2.14

n number of measurements made in the 28 animals, \( \frac{T_i}{2} \) one half of the contrast injection time in seconds, RMSE root-mean-square error