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Table 3 Correlations between percentage change in apparent diffusion coefficient (ADC) and applied acoustic energy, thermal dose volume (V240EM), and maximum temperature, showing that statistical significance was achieved at every measured time point, although the strength of the correlations varied

From: Value of diffusion-weighted imaging for monitoring tissue change during magnetic resonance-guided high-intensity focused ultrasound therapy in bone applications: an ex-vivo study

Time after sonication (min) Correlation between % change in mean ADC and:
Applied acoustic energy V240EMa Maximum temperature
< 1 r = 0.73 ρ = 0.61 r = 0.50
p < 0.001 p = 0.001 p = 0.010
1–5 r = 0.85 ρ = 0.80 r = 0.57
p < 0.001 p < 0.001 p = 0.002
6–10 r = 0.55 ρ = 0.48 r = 0.44
p = 0.003 p = 0.011 p = 0.023
11–15 r = 0.77 ρ = 0.73 r = 0.53
p < 0.001 p < 0.001 p = 0.005
16–20 r = 0.77 ρ = 0.76 r = 0.53
p < 0.001 p < 0.001 p = 0.005
21–50 r = 0.66 ρ = 0.52 r = 0.60
p = 0.001 p = 0.011 p = 0.003
  1. a Non-parametric Spearman’s test was used to correlate non-normally distributed V240EM data