Fig. 5From: Value of diffusion-weighted imaging for monitoring tissue change during magnetic resonance-guided high-intensity focused ultrasound therapy in bone applications: an ex-vivo studyADC time-intensity series for a 12 mm, b 8 mm, c 4 mm, and d 2 mm diameter cells. For each cell size, the magnitude of ADC change immediately after sonication was related to the acoustic power, with sustained ADC changes higher than limits of agreement (black dashed lines) only seen when the applied acoustic energy (determined by the power and duration of the exposure) exceeded approximately 1.5 kJ. Similar ADC changes were not seen in the control ROIs (red dashed lines). For image clarity of the separate time-intensity curves, the 20 W exposure data are not shown for the 4 mm cellBack to article page