Table 1 Foetal IVIM parameters and their repeatability across the study population
Structure and number (n) of individuals where the structure was repeatedly imaged | IVIM measurements | Within-subject variability (VAR%) | Subjects where bi-exponential fitting was insufficient, f and D* = 0 (n (%)) | ||||
|---|---|---|---|---|---|---|---|
Perfusion fraction f | Diffusion coefficient d (mm2/s) | Pseudo-diffusion coefficient D* (mm2/s) | Perfusion fraction f (%) | Diffusion coefficient d (%) | Pseudo- diffusion coefficient D* (%) | ||
Brain, frontal cortex (n = 11) | 0.142 ± 0.133 (0–0.54)a | 4.7 × 10–4 ± 9.9 × 10–5(2.9 × 10–4–7.7 × 10–4) | 9.5 × 10–3 ± 2.9 × 10–2(1 × 10–3–1.5 × 10–1) | 23.5 | 4.8 | 19.9 | 2 (18.2) |
Brain, frontal white matter (n = 8) | 0.087 ± 0.106 (0–0.377)a | 5.2 × 10–4 ± 1.3 × 10–4(2.9 × 10–4–7.8 × 10–4) | 7.3 × 10–3 ± 2.8 × 10–2(1 × 10–3–1.5 × 10–1) | 33.6 | 12.8 | 27.9 | 5 (62.5) |
Cerebellum (n = 9) | 0.135 ± 0.122 (0–0.419)a | 4.6 × 10–4 ± 1.1 × 10–4(2.3 × 10–4–6.9 × 10–4) | 9.4 × 10–3 ± 3.0 × 10–2(1 × 10–3–1.5 × 10–1) | 33.5 | 15.2 | 28.2 | 3 (33.3) |
Placenta (n = 16) | 0.28 ± 0.105 (0–0.479)a | 5.4 × 10–4 ± 8.2 × 10–5(2.9 × 10–4–6.8 × 10–4) | 4.7 × 10–3 ± 3.8 × 10–3(2.5 × 10–3–2.3 × 10–2) | 16.9 | 12.2 | 17 | 1 (6.3) |
Liver (n = 8) | 0.346 ± 0.101 (0.149–0.479) | 3.7 × 10–4 ± 8.7 × 10–5(2.3 × 10–4–5.9 × 10–4) | 2.6 × 10–3 ± 2.4 × 10–3(0–9.9 × 10–3) | 14.4 | 13.8 | 16.8 | 0 (0) |
Lung (n = 9) | 0.33 ± 0.112 (0.108–0.548) | 5.5 × 10–4 ± 9.2 × 10–5(4 × 10–4–8.1 × 10–4) | 2.5 × 10–3 ± 1.3 × 10–3(1 × 10–3–5.5 × 10–1) | 20.4 | 14.1 | 25.3 | 0 (0) |
Kidneys (n = 5) | 0.153 ± 0.09 (0–0.307)a | 4.2 × 10–4 ± 8.6 × 10–5(3.1 × 10–4–6.4 × 10–4) | 1.7 × 10–2 ± 4.2 × 10–2(1 × 10–3–1.5 × 10–1) | 36.2 | 17 | 30.1 | 2 (40) |