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European Radiology Experimental

Table 1 Growth and histology

From: Noninvasive assessment and quantification of tumour vascularisation using MRI and CT in a tumour model with modifiable angiogenesis – An animal experimental prospective cohort study

 

H1299

A549

All tumours

Non-co-transplanted

co-transplanted

p value

Non-co-transplanted

co-transplanted

p value

Non-co-transplanted

co-transplanted

p value

In vivo growth duration

[days]

49.0 (20)

18.0 (11)

<0.001

45.0 (10)

23.5 (15)

<0.001

45.0 (7)

22.0 (12)

<0.001

In vitro beads

[number/FOV]

1.1 (0.28)

1.3 (0.17)

0.009

1.1 (0.22)

1.3 (0.23)

0.032

1.1 (0.25)

1.3 (0.22)

0.001

In vitro MVD

[number/mm2]

89.7 (65.49)

203.1 (185.49)

0.036

114.6 (81.98)

153.4 (112.75)

0.018

110.8 (63.30)

171.4 (120)

0.002

  1. FOV field of vision, MVD microvessel density
  2. Overview of in vivo growth velocity until the imaging size of 2 cm was reached and in vitro histology and immunohistology. First and second column show results separately for both cell lines, in the third column data for both tumour cell lines were merged. Median (interquartile range)
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