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  1. Computed tomography (CT) is increasingly used in the clinical workup, and existing scan contains unused body composition data, potentially useful in a clinical setting. However, there is no healthy reference f...

    Authors: Mia Solholt Godthaab Brath, Marina Sahakyan, Esben Bolvig Mark, Jens Brøndum Frøkjær, Henrik Højgaard Rasmussen, Lasse Riis Østergaard and Ulla Møller Weinreich
    Citation: European Radiology Experimental 2023 7:26
    Content type: Original article Published on:

  2. To develop an isotropic three-dimensional (3D) T2 mapping technique for the quantitative assessment of the composition of knee cartilage with high accuracy and precision.

    Authors: Simon Kuhn, Aurélien Bustin, Aicha Lamri-Senouci, Simone Rumac, Jean-Baptiste Ledoux, Roberto Colotti, Jessica A. M. Bastiaansen, Jérôme Yerly, Julien Favre, Patrick Omoumi and Ruud B. van Heeswijk
    Citation: European Radiology Experimental 2023 7:25
    Content type: Original article Published on:

  3. We evaluated the early changes in left ventricular (LV) volumetric, functional, and tissue characteristics in human epidermal growth factor receptor 2 (HER2)-positive breast cancer patients treated with trastu...

    Authors: Sainan Cheng, Jianwei Wang, Yawen Wang, Linlin Qi, Fenglan Li, Jianing Liu, Jiaqi Chen, Yang Fan and Lizhi Xie
    Citation: European Radiology Experimental 2023 7:22
    Content type: Original article Published on:

  4. Artificial intelligence (AI) is transforming the field of medical imaging and has the potential to bring medicine from the era of ‘sick-care’ to the era of healthcare and prevention. The development of AI requ...

    Authors: Haridimos Kondylakis, Varvara Kalokyri, Stelios Sfakianakis, Kostas Marias, Manolis Tsiknakis, Ana Jimenez-Pastor, Eduardo Camacho-Ramos, Ignacio Blanquer, J. Damian Segrelles, Sergio López-Huguet, Caroline Barelle, Magdalena Kogut-Czarkowska, Gianna Tsakou, Nikolaos Siopis, Zisis Sakellariou, Paschalis Bizopoulos…
    Citation: European Radiology Experimental 2023 7:20
    Content type: Guideline/Position paper Published on:

  5. The potential enviromental impact of iodinated (ICAs) and gadolinium-based contrast agents (GBCAs) have recently come under scrutiny, considering the current nonselective wastewater treatment. However, their r...

    Authors: Moreno Zanardo, Andrea Cozzi, Rosanna Cardani, Laura Valentina Renna, Francesco Pomati, Luigi Asmundo, Giovanni Di Leo and Francesco Sardanelli
    Citation: European Radiology Experimental 2023 7:27
    Content type: Methodology Published on:

  6. Successful osseointegration of joint replacement implants is required for long-term implant survival. Accurate assessment of osseointegration could enable clinical discrimination of failed implants from other ...

    Authors: Mischa Woisetschläger, Ronald Booij, Erik Tesselaar, Edwin H. G. Oei and Jörg Schilcher
    Citation: European Radiology Experimental 2023 7:19
    Content type: Original article Published on:

  7. We investigated about optimization of contrast media (CM) dose or radiation dose in thoracoabdominal computed tomography angiography (CTA) by automated tube voltage selection (ATVS) system configuration and CM...

    Authors: Johannes Haubold, Sebastian Zensen, René Hosch, Benedikt Michael Schaarschmidt, Denise Bos, Bernhardt Schmidt, Thomas Flohr, Yan Li, Michael Forsting, Hubertus Pietsch, Felix Nensa and Gregor Jost
    Citation: European Radiology Experimental 2023 7:24
    Content type: Original article Published on:

  8. In this study, stent appearance in a novel silicon-based photon-counting computed tomography (Si-PCCT) prototype was compared with a conventional energy-integrating detector CT (EIDCT) system.

    Authors: Emma Verelst, Nico Buls, Johan De Mey, Koenraad Hans Nieboer, Frans Vandenbergh, Dominic Crotty, Paul Deak, Albert Sundvall, Staffan Holmin, Aron De Smet, Steven Provyn and Gert Van Gompel
    Citation: European Radiology Experimental 2023 7:23
    Content type: Original article Published on:

  9. We compared T1- and T2-weighted signal intensities of liver-specific (gadoxetate, gadobenate) and non-specific (gadoterate) gadolinium contrast agents (CAs) in a bile phantom.

    Authors: Johannes M. Froehlich, Leen Moussa, Natalie Guirguis, Andreas Gutzeit, David Wu, Sabine Sartoretti-Schefer, Dow-Mu Koh, Orpheus Kolokythas and Simon Matoori
    Citation: European Radiology Experimental 2023 7:21
    Content type: Original article Published on:

  10. The role of computed tomography (CT) in the diagnosis and characterization of coronavirus disease 2019 (COVID-19) pneumonia has been widely recognized. We evaluated the performance of a software for quantitati...

    Authors: Camilla Scapicchio, Andrea Chincarini, Elena Ballante, Luca Berta, Eleonora Bicci, Chandra Bortolotto, Francesca Brero, Raffaella Fiamma Cabini, Giuseppe Cristofalo, Salvatore Claudio Fanni, Maria Evelina Fantacci, Silvia Figini, Massimo Galia, Pietro Gemma, Emanuele Grassedonio, Alessandro Lascialfari…
    Citation: European Radiology Experimental 2023 7:18
    Content type: Original article Published on:

  11. Deep learning (DL) algorithms are playing an increasing role in automatic medical image analysis.

    Authors: Melissa Yeo, Bahman Tahayori, Hong Kuan Kok, Julian Maingard, Numan Kutaiba, Jeremy Russell, Vincent Thijs, Ashu Jhamb, Ronil V. Chandra, Mark Brooks, Christen D. Barras and Hamed Asadi
    Citation: European Radiology Experimental 2023 7:17
    Content type: Original article Published on:

  12. We investigated the feasibility of aneurysm sac embolization using a novel self-expanding porous shape memory polymer (SMP) device during endovascular aortic abdominal or thoracic aneurysm repair (EVAR).

    Authors: Alexander Massmann, Peter Fries, Roushanak Shayesteh-Kheslat, Arno Buecker, Patrick Berg and Felix Frenzel
    Citation: European Radiology Experimental 2023 7:12
    Content type: Original article Published on:

  13. Photon-counting detector computed tomography (PCD-CT) has the potential to provide superior image quality compared to energy-integrating detector computed tomography (EID-CT). We compared the two systems for e...

    Authors: Lena Sonnow, Nigar Salimova, Lea Behrendt, Frank K. Wacker, Marcus Örgel, Jochen Plagge and Friederike Weidemann
    Citation: European Radiology Experimental 2023 7:15
    Content type: Original article Published on:

  14. Radiomics, the field of image-based computational medical biomarker research, has experienced rapid growth over the past decade due to its potential to revolutionize the development of personalized decision su...

    Authors: Daniel Abler, Roger Schaer, Valentin Oreiller, Himanshu Verma, Julien Reichenbach, Orfeas Aidonopoulos, Florian Evéquoz, Mario Jreige, John O. Prior and Adrien Depeursinge
    Citation: European Radiology Experimental 2023 7:16
    Content type: Original article Published on:

  17. The role of imaging in pretreatment staging and management of prostate cancer (PCa) is constantly evolving. In the last decade, there has been an ever-growing interest in radiomics as an image analysis approac...

    Authors: Arnaldo Stanzione, Andrea Ponsiglione, Francesco Alessandrino, Giorgio Brembilla and Massimo Imbriaco
    Citation: European Radiology Experimental 2023 7:13
    Content type: Narrative review Published on:

  19. Gd levels are higher in tissues of animals with compromised renal function, but studies to compare levels after exposure to different macrocyclic gadolinium-based contrast agents (GBCAs) are lacking. We compar...

    Authors: Roberta Bonafè, Alessandra Coppo, Roberta Queliti, Simona Bussi, Federico Maisano, Miles A. Kirchin and Fabio Tedoldi
    Citation: European Radiology Experimental 2023 7:7
    Content type: Original article Published on:

  20. Our purpose was to evaluate the correlations between right ventricular (RV) late gadolinium enhancement (LGE) at cardiac magnetic resonance (CMR) in patients with tetralogy of Fallot (ToF) scheduled for pulmon...

    Authors: Caterina Beatrice Monti, Moreno Zanardo, Davide Capra, Giulia Lastella, Gianluca Guarnieri, Emilia Giambersio, Giulia Pasqualin, Francesco Sardanelli and Francesco Secchi
    Citation: European Radiology Experimental 2023 7:9
    Content type: Original article Published on:

  21. Contrast-enhanced mammography (CEM) is more available than MRI for breast cancer staging but may not be as sensitive in assessing disease extent. We compared CEM and MRI in this setting.

    Authors: Donna B. Taylor, Sally Burrows, Christobel M. Saunders, Paul M. Parizel and Angela Ives
    Citation: European Radiology Experimental 2023 7:8
    Content type: Original Article Published on:

  22. Coronary physiology assessment in rodents by ultrasound is an excellent noninvasive and easy to perform technique, including pulsed-wave Doppler (PWD) and myocardial contrast echocardiography (MCE). Both techn...

    Authors: Sebastian Billig, Marc Hein, Mare Mechelinck, David Schumacher, Anna B. Roehl, Dieter Fuchs, Rafael Kramann and Moritz Uhlig
    Citation: European Radiology Experimental 2023 7:6
    Content type: Original article Published on:

  23. To investigate hip implant-related metal artifacts on a 0.55-T system compared with 1.5-T and 3-T systems.

    Authors: Hanns-Christian Breit, Jan Vosshenrich, Martin Clauss, Thomas J. Weikert, Bram Stieltjes, Balázs K. Kovacs, Michael Bach and Dorothee Harder
    Citation: European Radiology Experimental 2023 7:5
    Content type: Original article Published on:

  24. To evaluate the feasibility of a novel approach for predicting hepatocellular carcinoma (HCC) response to drug-eluting beads transarterial chemoembolization (DEB-TACE) using computed tomography hepatic arterio...

    Authors: Ryosuke Taiji, Yuan-Mao Lin, Gouthami Chintalapani, Ethan Y. Lin, Steven Y. Huang, Armeen Mahvash, Rony Avritscher, Chien-An Liu, Rheun-Chuan Lee, Vivian Resende, Hideyuki Nishiofuku, Toshihiro Tanaka, Kimihiko Kichikawa, Ernst Klotz, Sanjay Gupta and Bruno C. Odisio
    Citation: European Radiology Experimental 2023 7:4
    Content type: Original article Published on:

  25. To develop a pipeline for automatic extraction of quantitative metrics and radiomic features from lung computed tomography (CT) and develop artificial intelligence (AI) models supporting differential diagnosis...

    Authors: Giulia Zorzi, Luca Berta, Francesco Rizzetto, Cristina De Mattia, Marco Maria Jacopo Felisi, Stefano Carrazza, Silvia Nerini Molteni, Chiara Vismara, Francesco Scaglione, Angelo Vanzulli, Alberto Torresin and Paola Enrica Colombo
    Citation: European Radiology Experimental 2023 7:3
    Content type: Original article Published on:

  26. Artificial intelligence (AI) and its different approaches, from machine learning to deep learning, are not new. We discuss here about the declaration of AI in the title of those articles dealing with AI. From ...

    Authors: Francesco Sardanelli, Isabella Castiglioni, Anna Colarieti, Simone Schiaffino and Giovanni Di Leo
    Citation: European Radiology Experimental 2023 7:2
    Content type: Hypothesis Published on:

  27. To assess the impact of the new version of a deep learning (DL) spectral reconstruction on image quality of virtual monoenergetic images (VMIs) for contrast-enhanced abdominal computed tomography in the rapid ...

    Authors: Djamel Dabli, Maeliss Loisy, Julien Frandon, Fabien de Oliveira, Azhar Mohamad Meerun, Boris Guiu, Jean-Paul Beregi and Joël Greffier
    Citation: European Radiology Experimental 2023 7:1
    Content type: Original article Published on:

  28. Coronary computed tomography angiography (CCTA) represents a common approach to the diagnostic workup of patients with suspected coronary artery disease. Technological development has recently allowed the inte...

    Authors: Tommaso D’Angelo, Simon Martin, Antonino Micari, Christian Booz, Alexandra Steyer, Alfredo Blandino, Ludovica R. Lanzafame, Vitali Koch, Giorgio Ascenti and Silvio Mazziotti
    Citation: European Radiology Experimental 2022 6:60
    Content type: Technical note Published on:

  29. Data shortage is a common challenge in developing computer-aided diagnosis systems. We developed a generative adversarial network (GAN) model to generate synthetic lung lesions mimicking ground glass nodules (...

    Authors: Zhixiang Wang, Zhen Zhang, Ying Feng, Lizza E. L. Hendriks, Razvan L. Miclea, Hester Gietema, Janna Schoenmaekers, Andre Dekker, Leonard Wee and Alberto Traverso
    Citation: European Radiology Experimental 2022 6:59
    Content type: Original article Published on:

    A Letter has been published.

  30. Magnetic resonance imaging (MRI) can be used to target tumour components in biopsy procedures, while the ability to precisely correlate histology and MRI signal is crucial for imaging biomarker validation. Roboti...

    Authors: Edward W. Johnston, Nicos Fotiadis, Craig Cummings, Jodie Basso, Toby Tyne, Joost Lameijer, Christina Messiou, Dow-Mu Koh and Jessica M. Winfield
    Citation: European Radiology Experimental 2022 6:55
    Content type: Original article Published on:

  31. Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease that can lead to cirrhosis and hepatic decompensation. However, predicting future outcomes in patients with PSC is challenging. Our a...

    Authors: Yashbir Singh, William A. Jons, John E. Eaton, Mette Vesterhus, Tom Karlsen, Ida Bjoerk, Andreas Abildgaard, Kristin Kaasen Jorgensen, Trine Folseraas, Derek Little, Aliya F. Gulamhusein, Kosta Petrovic, Anne Negard, Gian Marco Conte, Joseph D. Sobek, Jaidip Jagtap…
    Citation: European Radiology Experimental 2022 6:58
    Content type: Original article Published on:

  32. The cerebellum is involved in hyperactivity, fear, and anxiety disorders that could be induced by whole-brain irradiation (WBI). However, whether cerebellar irradiation alone (CIA) could induce these disorders...

    Authors: Yafeng Wang, Cuicui Xie, Yiran Xu, Yaodong Zhang, Changlian Zhu and Kai Zhou
    Citation: European Radiology Experimental 2022 6:57
    Content type: Original article Published on:

  33. NAVIGATOR is an Italian regional project boosting precision medicine in oncology with the aim of making it more predictive, preventive, and personalised by advancing translational research based on quantitativ...

    Authors: Rita Borgheresi, Andrea Barucci, Sara Colantonio, Gayane Aghakhanyan, Massimiliano Assante, Elena Bertelli, Emanuele Carlini, Roberto Carpi, Claudia Caudai, Diletta Cavallero, Dania Cioni, Roberto Cirillo, Valentina Colcelli, Andrea Dell’Amico, Domnico Di Gangi, Paola Anna Erba…
    Citation: European Radiology Experimental 2022 6:53
    Content type: Guideline/Position paper Published on:

  34. A new 72-channel receive array coil and sensitivity encoding, compressed (C-SENSE) and noncompressed (SENSE), were investigated to decrease the number of breath-holds (BHs) for cardiac magnetic resonance (CMR).

    Authors: Hugo Klarenberg, Mark Gosselink, Bram F. Coolen, Tim Leiner, Aart J. Nederveen, Adrianus J. Bakermans, Hildo J. Lamb, S. Matthijs Boekholdt, Martijn Froeling and Gustav J. Strijkers
    Citation: European Radiology Experimental 2022 6:54
    Content type: Original article Published on:

  36. To investigate the detection capabilities of myocardial perfusion defects of dual-energy computed tomography (CT) technology using time-resolved iodine-based maps for functional assessment of coronary stenosis...

    Authors: Johannes Hammel, Lorenz Birnbacher, Marcus R. Makowski, Franz Pfeiffer and Daniela Pfeiffer
    Citation: European Radiology Experimental 2022 6:51
    Content type: Original article Published on:

  37. We annually monitored stable compensated cirrhosis (CC) patients to evaluate serial variation in blood serum, liver stiffness, and multiparametric magnetic resonance imaging (mpMRI) measures to provide referen...

    Authors: Christopher R. Bradley, Eleanor F. Cox, Naaventhan Palaniyappan, Guruprasad P. Aithal, Susan T. Francis and Indra Neil Guha
    Citation: European Radiology Experimental 2022 6:52
    Content type: Original article Published on:

  38. The detection of peritoneal carcinomatosis in patients with ovarian cancer is crucial to establish the correct therapeutic planning (debulking surgery versus neoadjuvant chemotherapy).

    Authors: Giada Zorzetto, Andrea Coppola, Valeria Molinelli, Maria Gloria Angeretti, Jvan Casarin, Federico Fontana, Filippo Piacentino, Giulio Carcano, Fabio Ghezzi and Massimo Venturini
    Citation: European Radiology Experimental 2022 6:45
    Content type: Hypothesis Published on:

  39. The use of facemasks is one of the consequences of the coronavirus disease 2019 (COVID-19) pandemic. We used resting-state functional magnetic resonance imaging (fMRI) to search for subtle changes in brain fun...

    Authors: Sven Haller, Marie-Louise Montandon, Cristelle Rodriguez and Panteleimon Giannakopoulos
    Citation: European Radiology Experimental 2022 6:50
    Content type: Original article Published on:

  40. The aim of this study was to investigate the role of the lipid peak derived from 1H magnetic resonance (MR) spectroscopy in assessing cervical cancer prognosis, particularly in assessing response to neoadjuvant c...

    Authors: Miriam Dolciami, Rossella Canese, Claudia Testa, Angelina Pernazza, Giusi Santangelo, Innocenza Palaia, Carlo Della Rocca, Carlo Catalano and Lucia Manganaro
    Citation: European Radiology Experimental 2022 6:47
    Content type: Original article Published on:

  41. To evaluate simplified intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) for differentiating malignant versus benign breast lesions as (i) stand-alone tool and (ii) add-on to dynamic contrast-e...

    Authors: Petra Mürtz, Mark Tsesarskiy, Alois M. Sprinkart, Wolfgang Block, Oleksandr Savchenko, Julian A. Luetkens, Ulrike Attenberger and Claus C. Pieper
    Citation: European Radiology Experimental 2022 6:48
    Content type: Original article Published on:

  42. To validate the k-adaptive-t autocalibrating reconstruction for Cartesian sampling (kat-ARC), an exclusive sparse reconstruction technique for four-dimensional (4D) flow cardiac magnetic resonance (CMR) using ...

    Authors: Hosamadin Assadi, Bhalraam Uthayachandran, Rui Li, James Wardley, Tha H. Nyi, Ciaran Grafton-Clarke, Andrew J. Swift, Ana Beatriz Solana, Jean-Paul Aben, Kurian Thampi, David Hewson, Chris Sawh, Richard Greenwood, Marina Hughes, Bahman Kasmai, Liang Zhong…
    Citation: European Radiology Experimental 2022 6:46
    Content type: Original article Published on:

  43. We evaluated the role of radiomics applied to contrast-enhanced computed tomography (CT) in the detection of lymph node (LN) metastases in patients with known lung cancer compared to 18F-fluorodeoxyglucose positr...

    Authors: Boris Gorodetski, Philipp Hendrik Becker, Alexander Daniel Jacques Baur, Alexander Hartenstein, Julian Manuel Michael Rogasch, Christian Furth, Holger Amthauer, Bernd Hamm, Marcus Makowski and Tobias Penzkofer
    Citation: European Radiology Experimental 2022 6:44
    Content type: Original article Published on:

  44. In radiomics studies, differences in the volume of interest (VOI) are often inevitable and may confound the extracted features. We aimed to correct this confounding effect of VOI variability by applying parame...

    Authors: Laura J. Jensen, Damon Kim, Thomas Elgeti, Ingo G. Steffen, Lars-Arne Schaafs, Bernd Hamm and Sebastian N. Nagel
    Citation: European Radiology Experimental 2022 6:43
    Content type: Original article Published on:

  45. Though abnormal iron deposition has been reported in specific brain regions in multiple sclerosis (MS), no data exist about whether the overall quantity of iron in the brain is altered or not. We aimed to dete...

    Authors: Eman Hamdy, Aya Abdel Galeel, Ismail Ramadan, Dina Gaber, Haytham Mustafa and Jaidaa Mekky
    Citation: European Radiology Experimental 2022 6:49
    Content type: Original article Published on:

  46. Malignancy of lipomatous soft-tissue tumours diagnosis is suspected on magnetic resonance imaging (MRI) and requires a biopsy. The aim of this study is to compare the performances of MRI radiomic machine learn...

    Authors: Guillaume Fradet, Reina Ayde, Hugo Bottois, Mohamed El Harchaoui, Wassef Khaled, Jean-Luc Drapé, Frank Pilleul, Amine Bouhamama, Olivier Beuf and Benjamin Leporq
    Citation: European Radiology Experimental 2022 6:41
    Content type: Original article Published on:

  48. Acoustic noise in magnetic resonance imaging (MRI) negatively impacts patients. We assessed a silent gradient coil switched at 20 kHz combined with a T1-weighted magnetisation prepared rapid gradient-echo (MPRAGE...

    Authors: Sarah M. Jacobs, Edwin Versteeg, Anja G. van der Kolk, Leonie N. C. Visser, Ícaro A. F. Oliveira, Emiel van Maren, Dennis W. J. Klomp and Jeroen C. W. Siero
    Citation: European Radiology Experimental 2022 6:36
    Content type: Original article Published on:

  49. Computed tomography perfusion imaging (CTPI) by repeated scanning has clinical relevance but implies relatively high radiation exposure. We present a method to measure perfusion from two CT scan phases only, c...

    Authors: Massimo Cressoni, Andrea Cozzi, Simone Schiaffino, Paolo Cadringher, Paolo Vitali, Gianpaolo Basso, Davide Ippolito and Francesco Sardanelli
    Citation: European Radiology Experimental 2022 6:37
    Content type: Original article Published on:

  50. Magnetic resonance imaging (MRI) is an important part of breast cancer diagnosis and multimodal workup. It provides unsurpassed soft tissue contrast to analyse the underlying pathophysiology, and it is adopted...

    Authors: Matthias Dietzel, Rubina Manuela Trimboli, Moreno Zanardo, Rüdiger Schultz-Wendtland, Michael Uder, Paola Clauser, Francesco Sardanelli and Pascal A. T. Baltzer
    Citation: European Radiology Experimental 2022 6:42
    Content type: Narrative review Published on:
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