Exercise-related leg muscle signal changes: assessment using diffusion-weighted MRI

European Radiology Experimental

Table 1 Changes of ADC values (μm²/ms) and FA in muscle compartments on quantitative evaluation after each exercise

Parameter, compartment	Rest		Ex₅			Ex₁₀
Parameter, compartment	Mean	SD	Mean	SD	% change^a	Mean	SD	% change^a	% change^b
ADC, anterior	1.53	0.09	1.59	0.10	3.9	1.59	0.15	3.9	0
ADC, lateral	1.61	0.09	1.76	0.14	9.3^#	1.89	0.18	17.4^#	7.4^#
ADC, posterior deep	1.46	0.14	1.60	0.15	9.6	1.62	0.17	10.9	1.2
ADC, posterior intermediate	1.55	0.08	1.57	0.07	1.3	1.57	0.06	1.3	0
ADC, posterior superior	1.46	0.14	1.61	0.15	10.3^#	1.66	0.17	13.7^#	3.1
FA, anterior	0.38	0.03	0.38	0.03	0	0.39	0.05	2.6	2.6
FA, lateral	0.36	0.03	0.35	0.03	-2.8^#	0.33	0.02	-8.3^#	-5.7^#
FA, posterior deep	0.37	0.04	0.38	0.04	2.7	0.39	0.03	5.4	2.6
FA, posterior intermediate	0.35	0.03	0.36	0.02	2.8	0.35	0.02	0	-2.8
FA, posterior superior	0.35	0.03	0.33	0.02	-5.7^#	0.31	0.02	-11.4^#	-6.1^#

ADC Apparent diffusion coefficient, FA Fractional anisotropy, SD Standard deviation
^a% of changes relative to rest
^b% of changes relative to Ex₅
^#Statistically significant changes (p < 0.05)