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Table 3 Main studies on radiomics applications in the setting of active surveillance of prostate cancer (one example for each main potential application is proposed)

From: Beyond diagnosis: is there a role for radiomics in prostate cancer management?

First author [reference number]

Publication year

Country

Aim

Design

Sample size

Imaging modality

Main outcome

Potential impact

Xie [75]

2021

China

Patient selection

Retrospective, single-centre

59

MRI (radiomics)

A combination of texture features and ML-based analysis of ADC maps could predict PCa GG upgrading from Bx to RP

ML models may help clinicians select appropriate therapeutic strategy

Sushentsev [77]

2021

UK

Predicting progression

Retrospective, single-centre

64

MRI (radiomics)

PRECISE and delta-radiomics models achieved comparably good performance for predicting PCa progression in AS patients (AUC 78–84.4%)

To provide a quantitative assessment of MRI-guided follow-up AS patients, less dependent on reader experience

  1. AS Active surveillance, Bx Biopsy, GG Grade group, ML Machine Learning, PCa Prostate Cancer, PRECISE Prostate Cancer Radiological Estimation of Change in Sequential Evaluation, RP Radical prostatectomy