Fig. 3
From: Beyond diagnosis: is there a role for radiomics in prostate cancer management?
Prebiopsy MRI scan of a 58-year-old patient (PSA value of 6.12 ng/mL at the time of imaging) showing a PI-RADS 4 lesion in the posterior-lateral peripheral zone (right lobe) appearing hypointense on T2-weighted images (a) and exhibiting markedly restricted diffusion (b, high b value DWI; c, ADC map with red region of interest). Target biopsy confirmed the presence of prostatic adenocarcinoma (Gleason score 3 + 4). While a moderate capsule-tumour contact length can be appreciated on the T2-weighted images (a, white arrow), no bulging nor definitive signs of extracapsular extension are present and the radiologist staged the disease as locally confined. Based on the MRI report and considering the young age, the patient underwent nerve-sparing radical prostatectomy. Unfortunately, the pathology report on the surgical specimen revealed the presence of extracapsular disease extension and upgraded the Gleason score to 4 + 4. ADC Apparent diffusion coefficient, DWI Diffusion-weighted imaging, MRI Magnetic resonance imaging, PI-RADS Prostate Imaging-Reporting and Data System, PSA Prostate-specific antigen