Comparative assessment of coronary physiology using transthoracic pulsed-wave Doppler and myocardial contrast echocardiography in rats

European Radiology Experimental

Table 3 Myocardial contrast echocardiography measurements in eight rats, each under baseline conditions, and under adenosine or dobutamine stimulation

	Baseline		Adenosine			Dobutamine			p value²	η²
	Mean	SD	Mean	SD	p value¹	Mean	SD	p value¹	p value²	η²
normalised PE (%)	3.18	0.66	5.74	1.76	0.001	4.76	1.37	0.001	0.012	0.44
normalised WIR (%)	1.95	0.35	3.87	0.85	0.001	3.72	1.03	0.001	0.269	0.58
normalised AUC (%)	2.66	1.17	4.46	1.16	0.001	4.15	1.08	0.003	0.143	0.20
Myocardium PE (a.u.)	7.04	4.30	11.2	6.80	0.019	8.54	5.03	0.423	0.081	0.08
Myocardium WIR (a.u.)	1.97	1.40	3.02	1.88	0.029	2.62	1.56	0.219	0.281	0.07
Myocardium AUC (a.u.)	228	167	384	261	0.010	290	182	0.573	0.029	0.09
Ventricle PE (a.u.)	225	122	193	101	0.131	189	113	0.871	0.779	0.05
Ventricle WIR (a.u.)	102	65.5	76	38.5	0.078	83	60.6	0.345	0.561	0.04
Ventricle AUC (a.u.)	10,820	7,727	8,887	6,081	0.193	8,095	5,985	0.084	0.601	0.04

a.u. Arbitrary unit, AUC Area under the curve, p value¹ Adenosine or dobutamine versus baseline parameters; p value² Adenosine versus dobutamine, PE Peak enhancement, SD Standard deviation, WIR Wash-in rate, η² Effect size