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Fig. 3 | European Radiology Experimental

Fig. 3

From: A novel method for predicting hepatocellular carcinoma response to chemoembolization using an intraprocedural CT hepatic arteriography-based enhancement mapping: a proof-of-concept analysis

Fig. 3

Flowchart and two examples illustrating the proposed CTHA-EM ROI-based quantitative analysis. a Flowchart of quantitative assessment of residual tumor enhancement using CTHA-EM. b Two cases exemplifying ROI-based quantitative analysis. Top row: ROITumor (solid red circle) and ROInormal (dotted red circle) were placed on pre-treatment CTHA-EM images and transferred to the corresponding anatomical location on posttreatment CTHA-EM images. Bottom row: For cases with suspected residual enhancement, voxels with higher attenuation (orange dotted circle) were used for TPost-RE to avoid normalization bias from zero voxels due to subtraction of contrast stasis. Tpost-RE, Relative enhancement of tumor on posttreatment images; CTHA-EM, Computed tomography hepatic arteriography enhancement mapping; ROI, Region of interest

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