Coronary angiography using spectral detector dual-energy CT: is it the time to assess myocardial first-pass perfusion?

European Radiology Experimental

Table 1 Per-vessel analysis of maximal coronary stenosis, cFFR, and first-pass myocardial iodine distribution based on spectral CCTA

	Sex	Age (years)	Vessel	Maximal stenosis	cFFR	Minimal segmental iodine concentration (mg/mL)	Mean global iodine concentration (mg/mL)	Segmental versus global iodine concentration (p values) *
Patient 1	Male	57	LAD	54%	0.68	0.92	1.68	0.001
			LCx	51%	0.96	1.61		0.516
			RCA	10%	0.87	1.52		0.136
Patient 2	Female	63	LAD	37%	0.74	1.18	1.66	0.001
			LCx	21%	0.95	1.51		0.118
			RCA	40%	0.88	1.65		0.972
Patient 3	Male	74	LAD	75%	0.56	1.58	2.03	0.001
			LCx	45%	0.96	1.93		0.134
			RCA	48%	0.88	2.02		0.837
Patient 4	Male	75	LAD	70%	0.67	1.61	2.06	0.001
			LCx	58%	0.87	1.99		0.136
			RCA	68%	0.89	1.97		0.059

*Statistical analysis was performed using Graphpad Prism version 9.1 (GraphPad Software, San Diego, CA, USA). The differences between the minimal segmental iodine concentration and the mean global iodine concentration were performed by one-sample t test. Significant values are in bold. LAD Left anterior descending artery, LCx Left circumflex artery, RCA Right coronary artery, cFFR Calculated fractional flow reserve