Fig. 1
From: Simplified intravoxel incoherent motion DWI for differentiating malignant from benign breast lesions
Examples of axial diffusion-weighted imaging and intravoxel incoherent motion-parameter maps of breast lesions. From top to bottom, contrast-enhanced T1-weighted subtraction images (CE), original trace-weighted diffusion-weighted (DW) images with b = 0, 50, 800 s/mm2, and D1′ and f1′ colour-coded maps overlaid to DW images with b = 800 s/mm2 are given together with the used hot spot regions-of-interest (HS-ROIs). Invasive ductal carcinoma (case 1, 2 and 3, all G3 grade) typically show D1′ values between 0.6 and 1.2 × 10-3 mm2/s in areas with maximum hyperintensity on DW images with b = 800 s/mm2 (turquoise) and mixed f1′ values with hot spot values between 0.05 and 0.15 (turquoise). In case 1, central necrosis is present showing high D1′ values (red-yellow). Hyperintense area in case 4 was histologically diagnosed as fibrous mastopathy, ductal and lobular hyperplasia showing high D1′ of 2.0 × 10-3 mm2/s (red) and low f1′ of 0.01 (turquoise). Another case with fibrous mastopathy (case 5) showed also high D1′ of 1.4 × 10-3 mm2/s (yellow) but higher f1′ of 0.08