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Table 5 Correlation between HER2-positive tumours and magnetic resonance imaging features

From: Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

   HER2 +  χ2 analysis p-value Univariate analysis  
     OR (CI 95%)a p-value
No. of patients   5    
Tumour size Median (mm)
Range (mm)
25
12–36
   
 ≥ 2 cm   3/5 0.885 1.184 (0.192–7.316) 0.856
T2 intensity Hypointensity
Isointensity
Hyperintensity
3/5
2/5
0/5
0.322 1.844 (0.299–11.39)
2.081 (0.333–12.99)
Out of scale
0.510
0.433
Mass enhancement   5/5 0.268 Out of scale  
Rim enhancement   0/5 0.087 Out of scale  
Intralesional necrosis   1/5 0.285 0.317 (0.034–2.908) 0.309
Perilesional oedema   0/5 0.017 Out of scale  
Abnormal lymph nodes   2/5 0.910 1.111 (0.180–6.875) 0.910
Intensity-to-time curve Type I
Type II
Type III
0/5
1/5
4/5
0.720 Out of scale
0.721 (0.078–6.674)
2.112 (0.230–19.442)
0.774
0.509
ADC value Very low
Low
Intermediate
4/5
1/5
0/5
0.681 2.575 (0.279–23.75) 0.417 (0.045–3.845)
Out of scale
0.404
0.440
Extent of disease Unifocal
Multifocal
Multicentric
2/5
2/5
1/5
0.857 0.796 (0.129–4.915) 1.658 (0.267–10.31)
0.721 (0.078–6.674)
0.806
0.588
0.774
  1. aOR Odds ratio, CI Confidence interval, ADC Apparent diffusion coefficient