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Table 5 Correlation between HER2-positive tumours and magnetic resonance imaging features

From: Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

  

HER2 + 

χ2 analysis p-value

Univariate analysis

 
    

OR (CI 95%)a

p-value

No. of patients

 

5

   

Tumour size

Median (mm)

Range (mm)

25

12–36

   

 ≥ 2 cm

 

3/5

0.885

1.184 (0.192–7.316)

0.856

T2 intensity

Hypointensity

Isointensity

Hyperintensity

3/5

2/5

0/5

0.322

1.844 (0.299–11.39)

2.081 (0.333–12.99)

Out of scale

0.510

0.433

Mass enhancement

 

5/5

0.268

Out of scale

 

Rim enhancement

 

0/5

0.087

Out of scale

 

Intralesional necrosis

 

1/5

0.285

0.317 (0.034–2.908)

0.309

Perilesional oedema

 

0/5

0.017

Out of scale

 

Abnormal lymph nodes

 

2/5

0.910

1.111 (0.180–6.875)

0.910

Intensity-to-time curve

Type I

Type II

Type III

0/5

1/5

4/5

0.720

Out of scale

0.721 (0.078–6.674)

2.112 (0.230–19.442)

0.774

0.509

ADC value

Very low

Low

Intermediate

4/5

1/5

0/5

0.681

2.575 (0.279–23.75) 0.417 (0.045–3.845)

Out of scale

0.404

0.440

Extent of disease

Unifocal

Multifocal

Multicentric

2/5

2/5

1/5

0.857

0.796 (0.129–4.915) 1.658 (0.267–10.31)

0.721 (0.078–6.674)

0.806

0.588

0.774

  1. aOR Odds ratio, CI Confidence interval, ADC Apparent diffusion coefficient