Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

European Radiology Experimental

Table 4 Correlation between luminal B-like tumours and MRI features

		Luminal B	χ2 analysis p-value	Univariate analysis
				OR (CI 95%)^a	p-value
No. of patients		54
Tumour size	Median (mm) Range (mm)	20 6–86
≥ 2 cm		33/54	0.338	1.401 (0.702–2.793)	0.339
T2 intensity	Hypointensity Isointensity Hyperintensity	29/54 9/54 16/54	0.159	1.723 (0.868–3.420) 0.469 (0.201–1.098) 0.988 (0.470–2.076)	0.120 0.081 0.974
Mass enhancement		44/54	0.881	1.069 (0.449–2.544)	0.881
Rim enhancement		16/44	0.944	1.029 (0.469–2.255)	0.944
Intralesional necrosis		23/54	0.899	0.957 (0.482–1.900)	0.899
Perilesional oedema		32/54	0.204	1.558 (0.784–3.097)	0.205
Abnormal lymph nodes		23/54	0.334	1.410 (0.702–2.831)	0.335
Intensity-to-time curve	Type I Type II Type III	5/54 14/54 35/54	0.961	1.166 (0.351–3.877) 1.034 (0.475–2.250) 0.921 (0.451–1.882)	0.802 0.933 0.822
ADC value	Very low Low Intermediate	29/48 19/48 0/48	0.490	0.922 (0.440–1.932) 1.213 (0.576–2.554) Out of scale	0.830 0.611
Extent of disease	Unifocal Multifocal Multicentric	28/54 19/54 7/54	0.025	1.526 (0.770–3.022) 1.604 (0.766–3.357) 0.298 (0.120–0.740)	0.226 0.210 0.009