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Table 3 Association between luminal A-like breast cancer and magnetic resonance imaging features

From: Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

   Luminal A χ2
p-value
Univariate analysis   Multivariate analysis  
     OR (CI 95%)a p-value OR (CI 95%)a p-value
No. of patients   45      
Tumour size Median (mm)
Range (mm)
18
6–100
     
 ≥ 2 cm   19/45 0.024 0.438 (0.213–0.902) 0.025 0.411 (0.151–1.118) 0.082
T2 intensity Hypointensity
Isointensity
Hyperintensity
20/45
12/45
13/45
0.941 0.945 (0.464–1.927)
1.154 (0.513–2.595)
0.939 (0.431–2.043)
0.877
0.729
0.873
  
Mass enhancement   35/45 0.525 0.753 (0.313–1.810) 0.526   
Rim enhancement   3/35 < 0.001 0.101 (0.029–0.358) < 0.001 0.163 (0.040–0.657) 0.011
Intralesional necrosis   10/45 0.001 0.252 (0.112–0.566) 0.001 0.711 (0.228–2.220) 0.557
Perilesional
oedema
  12/45 < 0.001 0.199 (0.091–0.436) < 0.001 0.419 (0.149–1.175) 0.098
Abnormal lymph nodes   10/45 0.01 0.352 (0.157–0.791) 0.012 0.600 (0.212–1.693) 0.334
Intensity-to-time curve Type I
Type II
Type III
4/45
11/45
30/45
0.977 1.073 (0.306–3.769)
0.919 (0.405–2.083)
1.048 (0.495–2.216)
0.912
0.839
0.903
  
ADC value Very low
Low
Intermediate
20/40
19/40
1/40
0.182 0.491 (0.228–1.058)
1.944 (0.899–4.200)
2.154 (0.131–35.34)
0.069
0.091
0.591
  
Extent of disease Unifocal
Multifocal
Multicentric
19/45
10/45
16/45
0.148 0.828 (0.405–1.692)
0.599 (0.263–1.364)
2.097 (0.957–4.593)
0.605
0.222
0.064
  
  1. aOR Odds ratio, CI Confidence interval, ADC Apparent diffusion coefficient