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Table 3 Association between luminal A-like breast cancer and magnetic resonance imaging features

From: Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

  

Luminal A

χ2

p-value

Univariate analysis

 

Multivariate analysis

 
    

OR (CI 95%)a

p-value

OR (CI 95%)a

p-value

No. of patients

 

45

     

Tumour size

Median (mm)

Range (mm)

18

6–100

     

 ≥ 2 cm

 

19/45

0.024

0.438 (0.213–0.902)

0.025

0.411 (0.151–1.118)

0.082

T2 intensity

Hypointensity

Isointensity

Hyperintensity

20/45

12/45

13/45

0.941

0.945 (0.464–1.927)

1.154 (0.513–2.595)

0.939 (0.431–2.043)

0.877

0.729

0.873

  

Mass enhancement

 

35/45

0.525

0.753 (0.313–1.810)

0.526

  

Rim enhancement

 

3/35

< 0.001

0.101 (0.029–0.358)

< 0.001

0.163 (0.040–0.657)

0.011

Intralesional necrosis

 

10/45

0.001

0.252 (0.112–0.566)

0.001

0.711 (0.228–2.220)

0.557

Perilesional

oedema

 

12/45

< 0.001

0.199 (0.091–0.436)

< 0.001

0.419 (0.149–1.175)

0.098

Abnormal lymph nodes

 

10/45

0.01

0.352 (0.157–0.791)

0.012

0.600 (0.212–1.693)

0.334

Intensity-to-time curve

Type I

Type II

Type III

4/45

11/45

30/45

0.977

1.073 (0.306–3.769)

0.919 (0.405–2.083)

1.048 (0.495–2.216)

0.912

0.839

0.903

  

ADC value

Very low

Low

Intermediate

20/40

19/40

1/40

0.182

0.491 (0.228–1.058)

1.944 (0.899–4.200)

2.154 (0.131–35.34)

0.069

0.091

0.591

  

Extent of disease

Unifocal

Multifocal

Multicentric

19/45

10/45

16/45

0.148

0.828 (0.405–1.692)

0.599 (0.263–1.364)

2.097 (0.957–4.593)

0.605

0.222

0.064

  
  1. aOR Odds ratio, CI Confidence interval, ADC Apparent diffusion coefficient