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Table 2 Association between breast cancer grading (high grade) and magnetic resonance imaging features

From: Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?

   High grade χ2 analysis
p-value
Univariate analysis   Multivariate analysis  
     OR (CI 95%)b p-value OR (CI 95%)b p-value
No. of patients   73      
Tumour size Median (mm)
Range (mm)
52
34–75
     
 ≥ 2 cm   44/73 0.097 1.779 (0.899–3.518) 0.098   
T2 intensity Hypointensity
Isointensity
Hyperintensity
35/73
16/73
22/73
0.047a 1.842 (0.918–3.697)
0.399 (0.189–0.844)
1.267 (0.595–2.699)
0.086
0.016
0.539
0.385 (0.124–1.193) 0.098
Mass enhancement   55/73 0.921 1.040 (0.478–2.264) 0.921   
Rim enhancement   25/55 0.002 4.062 (1.607–10.271) 0.003 3.689 (1.011–3.467) 0.048
Intralesional necrosis   33/73 0.028 2.232 (1.084–4.597) 0.029 0.651 (0.193–2.195) 0.489
Perilesional oedema   45/73 0.001 3.214 (1.588–6.505) 0.001 2.105 (0.729–6.078) 0.169
Axillary adenopathy   32/73 0.008 2.732 (1.287–5.799) 0.009 2.241 (0.769–6.536) 0.139
Intensity-to-time curve Type I
Type II
Type III
2/73
21/73
50/73
0.245 0.268 (0.052–1.377)
1.093 (0.515–2.319)
1.250 (0.613–2.548)
0.115
0.817
0.539
  
ADC value Very low
Low
Intermediate
41/60
18/60
1/60
0.036a 2.937 (1.385–6.228)
0.339 (0.159–0.723)
0.873 (0.053–14.29)
0.005
0.005
0.924
2.191 (0.806–5.951) 0.124
Extent of disease Unifocal
Multifocal
Multicentric
29/73
27/73
17/73
0.011 0.494 (0.249–0.980)
3.522 (1.504–8.246)
0.759 (0.351–1.640)
0.044
0.004
0.483
2.247 (0.771–6.548) 0.138
  1. aBonferroni’s post hoc analysis found no significance. bOR Odds ratio, CI Confidence interval,  ADC Apparent diffusion coefficient