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Table 1 Sample descriptive analysis (n = 45)

From: Iron deposition in multiple sclerosis: overall load or distribution alteration?

  MS patients (n = 30) HC
(n = 15)
P1 P2
Total Benign (n = 10) Aggressive (n = 10) Naïve (n = 10)
Age in yearsa 34.5 ± 7.51 30.2 ± 5.63 37.3 ± .74 36.3 ± 10.09 36.27 ± 10.27 0.512 0.075
Gender, n (%)
 – Male 7 (23.3) 2 (20) 2 (20) 3 (30) 4 (26.7) 0.540 0.830
 – Female 23 (76.7) 8 (80) 8 (80) 7 (70) 11 (73.3)   
Disease durationb 7.0 (6–7.25) 6 (5–7.25) 6.50 (5.75–7.25) 7 (6–9) 0.379
DMT durationb 2 (0–3) 2.5 (1.75–3.5) 3 (2.75–4.25)    < 0.001*
EDSSb 3.5 (2.5–4.13) 2 (2–2) 4 (4–5.87) 3.5 (2.4–6.0) 0.001*
Total number of relapsesb 5.0 (4.0–7.0) 4 (3.75–6.25) 7 (6–11.25) 4.5 (2.75–6) 0.041*
SDMTa 33.30 ± 14.99 39.8 ± 13.06 27.1 ± 12.21 3.0 ± 17.76 0.168
9-HPTb
 – Right hand 23.86 (22.03–31.45) 21.6 (19.4–23.2) 28.1 (23.8–43.1) 24.1 (22.2–34.1) 0.011*
 – Left hand 28.11 (24.52–37.63) 25.1 (23.0–27.3) 30.9 (26.3–46.6) 30.8 (26.5–39.1)   0.052
T25FW testb 8.84 (7.09-12.82) 6.9 (6.5–8.3) 12.5 (8.6–17.4) 11.1 (7.4–16.6) 0.009*
  1. 9-HPT Nine hole-peg hole test, DMT Disease-modifying therapy, EDSS Expanded disability status scale, HC Healthy controls, MS Multiple sclerosis, n Number, SDMT Symbol digit modality test, T25FW Timed 25-foot walking, p1: Difference between the patients and HC, p2: Difference between subgroups of patients
  2. aMedian ± SD
  3. bMedian (IQR)
  4. *Statistically significant