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Table 1 Clinical endpoints and model type

From: A practical solution to estimate the sample size required for clinical prediction models generated from observational research on data

sTumor type

Description

Type of outcome

Neuroblastoma

5-year mortality risk

Binary

Neuroblastoma

Relapse/progression risk

Binary

Neuroblastoma

Time-to-death

Time-to-event

HR-Neuroblastoma

HR 5-year mortality risk

Binary

HR-Neuroblastoma

HR 5-year relapse/progression risk

Binary

HR-Neuroblastoma

HR-time to relapse/progression

Time-to-event

DIPG

1-year mortality risk

Binary

DIPG

2-year mortality risk

Binary

DIPG

1-year progression risk

Binary

DIPG

Time-to-death

Time-to-event

DIPG

Time-to-progression

Time-to-event

  1. List of the clinical endpoints for neuroblastoma, HR neuroblastoma and DIPG tumors for which the sample size was determined, and the type of outcome for each of these. DIPG diffuse intrinsic pontine glioma, HR high-risk