European Radiology Experimental

Table 5 Results on the hybrid validation for the two best models

From: MRI-based radiomics to predict response in locally advanced rectal cancer: comparison of manual and automatic segmentation on external validation in a multicentre study

	Hybrid validation: centre C
	AUC (95% CI)	ACC % (95% CI) [rate]	SE % (95% CI) [rate]	SP % (95% CI) [rate]	NPV % (95% CI) [rate]	PPV % (95% CI) [rate]
Train_MAN + Val_AUTO	0.69 (60–89)	75 (53–88) [21/28]	80 (50–95) [12/15]	69 (37–90) [9/13]	75 (54–86) [9/12]	75 (55–83) [12/16]
Train_AUTO + Val_MAN	0.62 (52–73)	64 (44–81) [18/28]	47 (21–73) [7/15]	85 (55–98) [11/13]	58 (45–70) [11/19]	78 (47–93) [7/9]

AUC Area under the curve, ACC Accuracy, NPV Negative predictive value, PPV Positive predictive value, SE Sensitivity, SP Specificity

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