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Table 1 Major clinical features of the cell lines used in this study

From: Influence of cellular models and individual factor in the biological response to chest CT scan exams

Cell lines Cell type Known gene mutation Cancer proneness Radiobiological status
200CLB Fibroblast Apparently healthy nd Radioresistance
RACKHAM01 Fibroblast NF1+/− Central and peripheral nervous system tumours Radiosensitivity and radiosusceptibility
RACKHAM12 Fibroblast NF1+/− Central and peripheral nervous system tumours Radiosensitivity and radiosusceptibility
RACKHAM39 Fibroblast NF1+/− Central and peripheral nervous system tumours Radiosensitivity and radiosusceptibility
01HNG Fibroblast nd (cancer patient) nd Radiosensitivity
02HNA Fibroblast nd (cancer patient) nd Radiosensitivity
13HNG Fibroblast nd (cancer patient) nd Radiosensitivity
GM03399 Fibroblast ATM+/− Mainly leukaemia, lymphoma Radioresistance and radiosusceptibility
85MA Fibroblast p53+/− Breast, brain, leukaemia, sarcoma Radioresistance and radiosusceptibility
201CLB Fibroblast BRCA2+/− Breast and/or ovarian cancer Radioresistance
202CLB Fibroblast BRCA1+/− Breast and/or ovarian cancer Radioresistance
203CLB Fibroblast BRCA1+/− Breast and/or ovarian cancer Radioresistance
201CLBepi Mammary epithelial cells BRCA2+/− Breast and/or ovarian cancer Radiosensitivity and radiosusceptibility
202CLBepi Mammary epithelial cells BRCA1+/− Breast and/or ovarian cancer Radiosensitivity and radiosusceptibility
203CLBepi Mammary epithelial cells BRCA1+/− Breast and/or ovarian cancer Radiosensitivity and radiosusceptibility
  1. nd Non-determined