Table 1 Major clinical features of the cell lines used in this study
From: Influence of cellular models and individual factor in the biological response to chest CT scan exams
Cell lines | Cell type | Known gene mutation | Cancer proneness | Radiobiological status |
|---|---|---|---|---|
200CLB | Fibroblast | Apparently healthy | nd | Radioresistance |
RACKHAM01 | Fibroblast | NF1+/− | Central and peripheral nervous system tumours | Radiosensitivity and radiosusceptibility |
RACKHAM12 | Fibroblast | NF1+/− | Central and peripheral nervous system tumours | Radiosensitivity and radiosusceptibility |
RACKHAM39 | Fibroblast | NF1+/− | Central and peripheral nervous system tumours | Radiosensitivity and radiosusceptibility |
01HNG | Fibroblast | nd (cancer patient) | nd | Radiosensitivity |
02HNA | Fibroblast | nd (cancer patient) | nd | Radiosensitivity |
13HNG | Fibroblast | nd (cancer patient) | nd | Radiosensitivity |
GM03399 | Fibroblast | ATM+/− | Mainly leukaemia, lymphoma | Radioresistance and radiosusceptibility |
85MA | Fibroblast | p53+/− | Breast, brain, leukaemia, sarcoma | Radioresistance and radiosusceptibility |
201CLB | Fibroblast | BRCA2+/− | Breast and/or ovarian cancer | Radioresistance |
202CLB | Fibroblast | BRCA1+/− | Breast and/or ovarian cancer | Radioresistance |
203CLB | Fibroblast | BRCA1+/− | Breast and/or ovarian cancer | Radioresistance |
201CLBepi | Mammary epithelial cells | BRCA2+/− | Breast and/or ovarian cancer | Radiosensitivity and radiosusceptibility |
202CLBepi | Mammary epithelial cells | BRCA1+/− | Breast and/or ovarian cancer | Radiosensitivity and radiosusceptibility |
203CLBepi | Mammary epithelial cells | BRCA1+/− | Breast and/or ovarian cancer | Radiosensitivity and radiosusceptibility |