Dark-field chest x-ray imaging: first experience in patients with alpha1-antitrypsin deficiency

European Radiology Experimental

Table 1 Characteristics of a healthy patient (#1) and four patients (#2–5) with alpha-1-antitrypsin deficiency (AATD)

Patient characteristics	#1	#2	#3	#4	#5
Gender	Male	Female	Male	Male	Male
Age (years)	33	41	48	73	55
AATD subtype	–	PiZZ	PiZZ	Pi00	PiZZ
Smoking (pack/years, stop)	Active	16, 2017	18, 2014	Never	13, 2009
Medication (year of start)	–	2018	2005	2014	2010
Duration of therapy	–	2	15	6	10
CAT-score	–	26	9	17	19
GOLD stage	–	4D	4A	2B	4B

Medication and duration of therapy refer to alpha-1-antitrypsin augmentation therapy. CAT Chronic obstructive pulmonary disease assessment test, GOLD Global Initiative for Chronic Obstructive Lung Disease, PiZZ Homozygous proteinase Z-alleles, Pi00 Homozygous 0 alleles