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Table 1 Characteristics of a healthy patient (#1) and four patients (#2–5) with alpha-1-antitrypsin deficiency (AATD)

From: Dark-field chest x-ray imaging: first experience in patients with alpha1-antitrypsin deficiency

Patient characteristics #1 #2 #3 #4 #5
Gender Male Female Male Male Male
Age (years) 33 41 48 73 55
AATD subtype PiZZ PiZZ Pi00 PiZZ
Smoking (pack/years, stop) Active 16, 2017 18, 2014 Never 13, 2009
Medication (year of start) 2018 2005 2014 2010
Duration of therapy 2 15 6 10
CAT-score 26 9 17 19
GOLD stage 4D 4A 2B 4B
  1. Medication and duration of therapy refer to alpha-1-antitrypsin augmentation therapy. CAT Chronic obstructive pulmonary disease assessment test, GOLD Global Initiative for Chronic Obstructive Lung Disease, PiZZ Homozygous proteinase Z-alleles, Pi00 Homozygous 0 alleles