Fig. 1From: Use of an antagonist of HMGB1 in mice affected by malignant mesothelioma: a preliminary ultrasound and optical imaging studyMouse survival in the first and second experiments. a The two mouse groups (n = 7 + 7) of the first experiment were BoxA-treated (red line) and phosphate-buffered saline-treated, i.e., controls (blue line). Their survival was evaluated up to the 70th day. BoxA-treated mice showed the greatest survival rate: 57.1% at the 70th day after the inoculation of malignant mesothelioma cells. b In the second experiment, the survival curves of controls and BoxA-treated mice were evaluated up to the 34th day after the inoculation and up to day 73 both for rechallenged and non-rechallenged mice: BoxA-treated mice had a highly significant survival rate than controls (same line colors as for panel a)Back to article page